Detailed information NTG0510540

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: STR1_RS04730
• Genome accession: NZ_CP065486
• Coordinates: 910537..912684 (-)
• Length: 715 a.a.
• NCBI ID: WP_095559353.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain R1
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 905537..917684

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR1_RS04705 (STR1_04705)	-	905901..906848 (+)	948	WP_095559349.1	dihydroorotate dehydrogenase	-
STR1_RS04710 (STR1_04710)	cas1	906987..907991 (+)	1005	WP_095559350.1	CRISPR-associated endonuclease Cas1	-
STR1_RS04715 (STR1_04715)	cas2	907991..908320 (+)	330	WP_014608281.1	CRISPR-associated endonuclease Cas2	-
STR1_RS04720 (STR1_04720)	-	908674..909096 (+)	423	WP_095559351.1	rRNA adenine dimethyltransferase family protein	-
STR1_RS04725 (STR1_04725)	-	909131..910525 (-)	1395	WP_095559352.1	bacteriocin secretion accessory protein	-
STR1_RS04730 (STR1_04730)	comA/nlmT	910537..912684 (-)	2148	WP_095559353.1	peptide cleavage/export ABC transporter	Regulator
STR1_RS04735 (STR1_04735)	-	912959..913180 (+)	222	WP_101415610.1	Blp family class II bacteriocin	-
STR1_RS04740 (STR1_04740)	-	913232..913459 (+)	228	WP_058621356.1	bacteriocin class II family protein	-
STR1_RS04745 (STR1_04745)	-	913481..913864 (+)	384	WP_095559354.1	hypothetical protein	-
STR1_RS04750 (STR1_04750)	-	913861..914064 (+)	204	Protein_891	garvicin Q family class II bacteriocin	-
STR1_RS04755 (STR1_04755)	-	914076..914378 (+)	303	WP_015695689.1	bacteriocin immunity protein	-
STR1_RS04760 (STR1_04760)	-	914536..914769 (+)	234	WP_095559355.1	Blp family class II bacteriocin	-
STR1_RS04765 (STR1_04765)	-	914959..915216 (+)	258	WP_095559356.1	garvicin Q family class II bacteriocin	-
STR1_RS04770 (STR1_04770)	-	915216..915524 (+)	309	WP_018364976.1	bacteriocin immunity protein	-
STR1_RS04775 (STR1_04775)	-	915899..916078 (+)	180	WP_095559357.1	hypothetical protein	-
STR1_RS04780 (STR1_04780)	-	916321..916521 (+)	201	WP_006531882.1	bacteriocin class II family protein	-
STR1_RS04785 (STR1_04785)	-	916547..916729 (+)	183	WP_006531883.1	Blp family class II bacteriocin	-
STR1_RS04790 (STR1_04790)	-	917346..917576 (+)	231	WP_043878356.1	bacteriocin	-

Sequence

Protein

• Length: 715 a.a.
• Molecular weight: 80092.91 Da
• Isoelectric Point: 7.0609

>NTDB_id=510540 STR1_RS04730 WP_095559353.1 910537..912684(-) (comA/nlmT) [Streptococcus thermophilus strain R1]
MRRYKYVSQIDLRDCGVAALASVAKHYGSDFSLAHLRELAKTTKEGTTALGIVEAAKAIGFETRAIQANMELFDMADIPY
PFIVHVNKEGKLQHYYVVYKAKKNHLIIGDPDPSVKVTKMPKERFEKEWTGVAIFLAPAPHYQPHKDKKNGLTSFLPIIF
KQKALLTYIILASLLVTLINIVGSYYLQGILDDYIPNHLQSTLGIVSVGLIVTYIMQQIMSFSQNYLLVVLSQRLTIDVI
LSYIRHIFELPMSFFATRRTGEVISRFTDANSIIDALASTILSLFLDVSILFIVGSVLILQNANLFFITLIALPIYAIII
LAFMKPFERMNHDVMQANSMVSSAIIEDINGIETIKSLTSEEVRYQNIDREFVDYLDKSFTLSKYEAVQTSLKQGAQLIL
NVAILWYGSHLVMAGNISVGQLITYNTLLSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVSSEFDGKQLLNDSHFLQG
DIVFDDVSYKYGFGRDTLSHVNLHIKKGEKISLVGISGSGKTTLAKMIVNFYTPNHGQITLGGYDLKTIDKKAIRQYINY
LPQQSYVFSGTILENLTLGAPDNITQEEILKACEIAEIRADIELMPLAYHTELSDGAGLSGGQKQRLALARALLTQAPVL
ILDEATSGLDVLTEKRVIKNLLSLTDKTIIFVAHRLSIAEQSDRVIVLDKGQVIEEGHHKQLIQNQGFYAQLFHE

Nucleotide

• Length: 2148 bp

>NTDB_id=510540 STR1_RS04730 WP_095559353.1 910537..912684(-) (comA/nlmT) [Streptococcus thermophilus strain R1]
ATGAGGAGATACAAGTATGTTAGTCAGATTGATTTGCGAGATTGTGGTGTGGCAGCTTTGGCGTCAGTTGCCAAGCATTA
TGGATCTGATTTCTCACTGGCACACCTAAGGGAATTAGCTAAAACAACTAAGGAAGGGACGACAGCGTTAGGGATAGTCG
AGGCAGCTAAAGCCATTGGCTTTGAAACACGCGCCATTCAAGCTAACATGGAACTGTTTGATATGGCCGATATTCCCTAT
CCTTTTATTGTTCATGTTAACAAAGAAGGCAAACTGCAGCACTATTATGTCGTTTACAAAGCTAAGAAAAACCACCTTAT
CATCGGTGATCCAGACCCCAGTGTCAAAGTGACCAAAATGCCCAAGGAGCGCTTTGAAAAGGAATGGACAGGTGTCGCCA
TTTTCTTAGCACCTGCTCCGCATTATCAACCGCATAAAGATAAGAAAAATGGCTTAACAAGCTTTTTACCAATTATTTTC
AAACAAAAGGCACTGCTAACTTATATCATTCTGGCAAGTTTGCTCGTGACCTTGATTAACATTGTTGGGTCTTACTATTT
GCAAGGAATCTTAGACGATTATATTCCTAATCATTTGCAATCCACTCTTGGCATTGTCTCGGTTGGGTTGATTGTAACCT
ACATAATGCAACAAATCATGAGCTTTTCACAAAATTATTTACTTGTTGTGCTGAGCCAACGGTTAACAATTGACGTGATT
TTGTCTTATATTCGTCACATTTTTGAATTGCCCATGTCTTTTTTTGCCACAAGGCGGACAGGTGAAGTGATCTCACGTTT
CACCGATGCTAACTCGATTATTGATGCACTGGCATCAACGATTCTCTCTTTATTTTTAGATGTGAGTATTTTGTTTATTG
TCGGAAGTGTCTTAATTCTGCAAAATGCCAATCTCTTTTTCATCACCTTAATAGCATTGCCTATCTATGCTATTATTATT
TTGGCTTTTATGAAGCCTTTTGAGCGAATGAATCACGATGTCATGCAAGCCAATTCTATGGTTAGCTCTGCGATTATCGA
AGATATCAATGGTATTGAAACGATTAAATCTTTGACTAGTGAGGAAGTCCGTTATCAAAATATTGACCGTGAATTTGTGG
ATTATTTGGATAAAAGTTTTACGCTTAGTAAGTATGAAGCTGTGCAAACGTCGTTAAAACAGGGAGCACAGCTAATTTTA
AACGTCGCTATTCTCTGGTATGGTTCACATTTAGTCATGGCTGGGAACATTTCAGTAGGTCAATTGATTACTTACAATAC
GCTTCTGTCGTACTTTACAACACCAATGGAAAATATTATTAATCTGCAAACCAAACTACAATCTGCCAAAGTAGCTAACA
ATCGTCTCAACGAAGTTTACTTAGTGTCATCTGAATTTGATGGCAAACAACTCTTAAATGACAGCCATTTTCTACAAGGA
GATATTGTTTTTGATGATGTTTCTTATAAATATGGTTTTGGTCGTGACACGCTGAGTCATGTGAATTTACACATTAAGAA
AGGTGAAAAAATTAGCCTAGTTGGTATCAGCGGTTCTGGTAAGACAACCTTAGCTAAAATGATTGTCAATTTTTACACAC
CTAACCATGGACAGATTACCCTTGGTGGCTACGATTTAAAAACCATTGATAAAAAAGCCATTCGCCAATACATTAATTAC
CTACCACAACAGTCTTACGTCTTTTCAGGGACGATTTTAGAAAATTTAACCTTGGGAGCACCTGACAATATCACGCAAGA
AGAAATTCTGAAAGCTTGTGAAATCGCTGAAATCCGTGCTGATATTGAATTGATGCCACTAGCATACCATACCGAACTTT
CAGATGGTGCTGGGTTATCTGGTGGGCAAAAGCAACGTTTAGCTTTAGCACGCGCTTTACTGACACAAGCTCCCGTCTTG
ATTTTAGATGAAGCCACAAGTGGTCTTGATGTTCTAACGGAAAAACGTGTGATTAAAAATTTACTATCTCTCACAGACAA
AACTATTATTTTTGTTGCCCACCGTTTGAGCATTGCTGAACAATCTGACCGTGTCATTGTTCTAGATAAAGGACAAGTTA
TCGAAGAAGGGCATCATAAACAACTCATCCAAAATCAAGGTTTCTATGCACAGTTATTTCATGAATAA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (3-140)

• ABC transporter transmembrane region (ABC_membrane) (166-436)

• ABC transporter (ABC_tran) (498-647)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.827	99.72	0.706
comA	Streptococcus mitis NCTC 12261	67.465	99.301	0.67
comA	Streptococcus pneumoniae D39	67.232	99.021	0.666
comA	Streptococcus pneumoniae R6	67.232	99.021	0.666
comA	Streptococcus pneumoniae Rx1	67.232	99.021	0.666
comA	Streptococcus mitis SK321	66.901	99.301	0.664
comA	Streptococcus gordonii str. Challis substr. CH1	66.48	99.72	0.663
comA	Streptococcus pneumoniae TIGR4	66.949	99.021	0.663