Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   STR1_RS00980 Genome accession   NZ_CP065486
Coordinates   177877..178626 (+) Length   249 a.a.
NCBI ID   WP_095559217.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain R1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 172877..183626
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR1_RS00950 (STR1_00945) - 173453..173623 (+) 171 WP_023909348.1 hypothetical protein -
  STR1_RS00955 (STR1_00950) - 173710..173817 (+) 108 WP_002949251.1 LPXTG cell wall anchor domain-containing protein -
  STR1_RS00960 (STR1_00955) - 173904..174644 (-) 741 WP_002949253.1 amino acid ABC transporter ATP-binding protein -
  STR1_RS00965 (STR1_00960) - 174644..176194 (-) 1551 WP_011680665.1 ABC transporter substrate-binding protein/permease -
  STR1_RS00970 (STR1_00965) - 176397..177251 (+) 855 WP_023909349.1 undecaprenyl-diphosphate phosphatase -
  STR1_RS00975 (STR1_00970) - 177303..177611 (-) 309 WP_306496352.1 DUF3021 family protein -
  STR1_RS00980 (STR1_00975) mecA 177877..178626 (+) 750 WP_095559217.1 adaptor protein MecA Regulator
  STR1_RS00985 (STR1_00980) - 178630..179787 (+) 1158 WP_014621088.1 MraY family glycosyltransferase -
  STR1_RS00990 (STR1_00985) sufC 179948..180718 (+) 771 WP_002947634.1 Fe-S cluster assembly ATPase SufC -
  STR1_RS00995 (STR1_00990) sufD 180755..182017 (+) 1263 WP_011680669.1 Fe-S cluster assembly protein SufD -
  STR1_RS01000 (STR1_00995) - 182071..183303 (+) 1233 WP_011680670.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29140.66 Da        Isoelectric Point: 4.0481

>NTDB_id=510515 STR1_RS00980 WP_095559217.1 177877..178626(+) (mecA) [Streptococcus thermophilus strain R1]
MEMKQISETTLKIMITMEDLEEHGMELKDLLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMEDYSGLSPEEFLKALEDNFMDKGDIEAHHKLEEHDKTLKEVDETMTEPAKEVAEETIREDYTHYVLAF
SDFDQVVTFAQGLKNVSVEGSEFYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRPYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=510515 STR1_RS00980 WP_095559217.1 177877..178626(+) (mecA) [Streptococcus thermophilus strain R1]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAGCT
GAAAGATCTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGTTGAGCTTCCGTGTCACGCCACGAAAGGATCGTGTGGATGTTTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAATGATTTGTCAGATATGGAAGACTATTCAGGACTTTCTCCAGAAGAATTCCTCAAAGCTCT
TGAAGATAACTTTATGGATAAGGGAGATATTGAAGCCCACCATAAGCTCGAAGAGCATGATAAGACCTTGAAAGAGGTTG
ATGAGACTATGACAGAGCCGGCTAAGGAAGTGGCTGAGGAAACTATTCGTGAAGATTATACTCACTATGTCTTGGCTTTC
TCTGACTTTGATCAAGTAGTGACCTTTGCGCAAGGTTTGAAGAATGTGTCAGTGGAGGGTTCTGAATTTTATAAACTTGG
TGATGTCTACTATATGACTATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTCCCTATCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTATTACAAGCAACGAAATGGAGCTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

99.598

100

0.996
  mecA Streptococcus thermophilus LMG 18311

98.795

100

0.988
  mecA Streptococcus mutans UA159

57.377

97.992

0.562
  mecA Streptococcus pneumoniae Rx1

46.185

100

0.462
  mecA Streptococcus pneumoniae D39

46.185

100

0.462
  mecA Streptococcus pneumoniae R6

46.185

100

0.462
  mecA Streptococcus pneumoniae TIGR4

46.185

100

0.462