Detailed information
Bioinformatically predicted
Overview
| Name | stkP/pknB | Type | Regulator |
| Locus tag | STCNRZ1151_RS06670 | Genome accession | NZ_CP065483 |
| Coordinates | 1271059..1272930 (-) | Length | 623 a.a. |
| NCBI ID | WP_011226292.1 | Uniprot ID | Q5M3J0 |
| Organism | Streptococcus thermophilus strain CNRZ1151 | ||
| Function | activate comX expression (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1269295..1330673 | 1271059..1272930 | within | 0 |
Gene organization within MGE regions
Location: 1269295..1330673
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| STCNRZ1151_RS06660 (STCNRZ1151_06665) | liaF | 1269303..1270001 (-) | 699 | WP_011226289.1 | cell wall-active antibiotics response protein LiaF | - |
| STCNRZ1151_RS06665 | - | 1270267..1270422 (-) | 156 | WP_011226290.1 | ion channel | - |
| STCNRZ1151_RS06670 (STCNRZ1151_06675) | stkP/pknB | 1271059..1272930 (-) | 1872 | WP_011226292.1 | Stk1 family PASTA domain-containing Ser/Thr kinase | Regulator |
| STCNRZ1151_RS06675 (STCNRZ1151_06680) | - | 1272930..1273667 (-) | 738 | WP_002946881.1 | Stp1/IreP family PP2C-type Ser/Thr phosphatase | - |
| STCNRZ1151_RS06680 (STCNRZ1151_06685) | rsmB | 1273711..1275033 (-) | 1323 | WP_014608533.1 | 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB | - |
| STCNRZ1151_RS06685 (STCNRZ1151_06690) | fmt | 1275023..1275958 (-) | 936 | WP_002951411.1 | methionyl-tRNA formyltransferase | - |
| STCNRZ1151_RS06690 (STCNRZ1151_06695) | - | 1275976..1278372 (-) | 2397 | WP_011227404.1 | primosomal protein N' | - |
| STCNRZ1151_RS06695 (STCNRZ1151_06700) | rpoZ | 1278514..1278828 (-) | 315 | WP_002951415.1 | DNA-directed RNA polymerase subunit omega | - |
| STCNRZ1151_RS06700 (STCNRZ1151_06705) | gmk | 1278850..1279479 (-) | 630 | WP_011226296.1 | guanylate kinase | - |
| STCNRZ1151_RS06705 (STCNRZ1151_06710) | ftsY | 1279712..1281103 (-) | 1392 | WP_011226297.1 | signal recognition particle-docking protein FtsY | - |
| STCNRZ1151_RS06710 (STCNRZ1151_06715) | - | 1281117..1281932 (-) | 816 | WP_011227405.1 | Cof-type HAD-IIB family hydrolase | - |
| STCNRZ1151_RS06715 (STCNRZ1151_06720) | - | 1281925..1282719 (-) | 795 | WP_059257398.1 | HAD hydrolase family protein | - |
| STCNRZ1151_RS06720 (STCNRZ1151_06725) | - | 1282902..1283279 (+) | 378 | WP_011226300.1 | GntR family transcriptional regulator | - |
| STCNRZ1151_RS06725 (STCNRZ1151_06730) | - | 1283284..1283982 (+) | 699 | WP_011226301.1 | ABC transporter ATP-binding protein | - |
| STCNRZ1151_RS06730 (STCNRZ1151_06735) | - | 1283994..1284779 (+) | 786 | WP_002951425.1 | hypothetical protein | - |
| STCNRZ1151_RS09645 (STCNRZ1151_06740) | - | 1284829..1285314 (-) | 486 | Protein_1263 | ATP-binding cassette domain-containing protein | - |
| STCNRZ1151_RS09650 (STCNRZ1151_06745) | - | 1285346..1285660 (-) | 315 | Protein_1264 | TatD family hydrolase | - |
| STCNRZ1151_RS06745 (STCNRZ1151_06750) | - | 1286009..1287214 (+) | 1206 | WP_011227415.1 | OFA family MFS transporter | - |
| STCNRZ1151_RS06750 (STCNRZ1151_06755) | - | 1287260..1288612 (-) | 1353 | Protein_1266 | IS3 family transposase | - |
| STCNRZ1151_RS06755 (STCNRZ1151_06760) | pta | 1288698..1289681 (-) | 984 | WP_011227420.1 | phosphate acetyltransferase | - |
| STCNRZ1151_RS06760 (STCNRZ1151_06765) | - | 1289695..1290591 (-) | 897 | WP_011226316.1 | RluA family pseudouridine synthase | - |
| STCNRZ1151_RS06765 (STCNRZ1151_06770) | - | 1290588..1291424 (-) | 837 | WP_041827075.1 | NAD kinase | - |
| STCNRZ1151_RS06770 (STCNRZ1151_06775) | - | 1291396..1292070 (-) | 675 | WP_002951443.1 | GTP pyrophosphokinase family protein | - |
| STCNRZ1151_RS06775 (STCNRZ1151_06780) | - | 1292166..1292741 (+) | 576 | WP_002951444.1 | CYTH domain-containing protein | - |
| STCNRZ1151_RS06780 (STCNRZ1151_06785) | - | 1293104..1294075 (+) | 972 | WP_002951446.1 | ribose-phosphate diphosphokinase | - |
| STCNRZ1151_RS06785 (STCNRZ1151_06790) | - | 1294079..1295191 (+) | 1113 | WP_002948029.1 | cysteine desulfurase family protein | - |
| STCNRZ1151_RS06790 (STCNRZ1151_06795) | - | 1295193..1295540 (+) | 348 | WP_002948028.1 | DUF1831 domain-containing protein | - |
| STCNRZ1151_RS06795 (STCNRZ1151_06800) | - | 1295684..1296343 (+) | 660 | WP_041827076.1 | redox-sensing transcriptional repressor Rex | - |
| STCNRZ1151_RS06800 (STCNRZ1151_06805) | - | 1296336..1297031 (+) | 696 | WP_011227423.1 | gamma-glutamyl-gamma-aminobutyrate hydrolase family protein | - |
| STCNRZ1151_RS06805 (STCNRZ1151_06810) | radC | 1297084..1297770 (-) | 687 | WP_011227424.1 | DNA repair protein RadC | - |
| STCNRZ1151_RS06810 (STCNRZ1151_06815) | - | 1297949..1299289 (-) | 1341 | WP_231108743.1 | DUF2142 domain-containing protein | - |
| STCNRZ1151_RS06815 (STCNRZ1151_06820) | - | 1299438..1301183 (-) | 1746 | WP_011227426.1 | rhamnan synthesis F family protein | - |
| STCNRZ1151_RS06820 (STCNRZ1151_06825) | - | 1301185..1302885 (-) | 1701 | WP_041827077.1 | glycosyltransferase family 4 protein | - |
| STCNRZ1151_RS06825 (STCNRZ1151_06830) | - | 1302903..1304105 (-) | 1203 | WP_059257395.1 | ABC transporter ATP-binding protein | - |
| STCNRZ1151_RS06830 (STCNRZ1151_06835) | - | 1304105..1304911 (-) | 807 | WP_011227429.1 | ABC transporter permease | - |
| STCNRZ1151_RS06835 (STCNRZ1151_06840) | - | 1304911..1305852 (-) | 942 | WP_011227430.1 | glycosyltransferase family 2 protein | - |
| STCNRZ1151_RS06840 (STCNRZ1151_06845) | cps2T | 1305849..1306997 (-) | 1149 | WP_011227431.1 | beta 1-4 rhamnosyltransferase Cps2T | - |
| STCNRZ1151_RS06845 (STCNRZ1151_06850) | - | 1307116..1307898 (-) | 783 | WP_011227432.1 | glycosyltransferase family A protein | - |
| STCNRZ1151_RS06850 (STCNRZ1151_06855) | - | 1307899..1308231 (-) | 333 | WP_011227433.1 | DUF2304 domain-containing protein | - |
| STCNRZ1151_RS06855 (STCNRZ1151_06860) | - | 1308237..1308932 (-) | 696 | WP_173405413.1 | glycosyltransferase family 2 protein | - |
| STCNRZ1151_RS06860 (STCNRZ1151_06865) | - | 1309016..1309488 (-) | 473 | Protein_1288 | glycosyltransferase family 2 protein | - |
| STCNRZ1151_RS06865 (STCNRZ1151_06870) | - | 1309553..1310539 (-) | 987 | WP_011227437.1 | glycosyltransferase family 2 protein | - |
| STCNRZ1151_RS06870 (STCNRZ1151_06875) | - | 1310536..1311795 (-) | 1260 | WP_011227438.1 | oligosaccharide flippase family protein | - |
| STCNRZ1151_RS06875 (STCNRZ1151_06880) | rfbD | 1311916..1312767 (-) | 852 | WP_014621820.1 | dTDP-4-dehydrorhamnose reductase | - |
| STCNRZ1151_RS06880 (STCNRZ1151_06885) | - | 1312885..1313811 (-) | 927 | WP_011227439.1 | glycosyltransferase family 2 protein | - |
| STCNRZ1151_RS06885 (STCNRZ1151_06890) | - | 1313821..1314156 (-) | 336 | WP_002891474.1 | metal-sulfur cluster assembly factor | - |
| STCNRZ1151_RS06890 (STCNRZ1151_06895) | rpoD | 1314210..1315319 (-) | 1110 | WP_011227440.1 | RNA polymerase sigma factor RpoD | - |
| STCNRZ1151_RS06895 (STCNRZ1151_06900) | dnaG | 1315323..1317134 (-) | 1812 | WP_011227441.1 | DNA primase | - |
| STCNRZ1151_RS06900 (STCNRZ1151_06905) | rpsU | 1317506..1317682 (-) | 177 | WP_011226340.1 | 30S ribosomal protein S21 | - |
| STCNRZ1151_RS06905 (STCNRZ1151_06910) | - | 1318063..1319016 (+) | 954 | WP_041826943.1 | IS30 family transposase | - |
| STCNRZ1151_RS06910 (STCNRZ1151_06915) | - | 1319122..1319916 (-) | 795 | WP_011227442.1 | ABC transporter substrate-binding protein | - |
| STCNRZ1151_RS06915 (STCNRZ1151_06920) | - | 1320009..1321118 (-) | 1110 | WP_041828295.1 | aminotransferase | - |
| STCNRZ1151_RS06920 (STCNRZ1151_06925) | - | 1321465..1322262 (-) | 798 | WP_059257394.1 | transporter substrate-binding domain-containing protein | - |
| STCNRZ1151_RS06925 (STCNRZ1151_06930) | - | 1322259..1323089 (-) | 831 | WP_041828297.1 | transporter substrate-binding domain-containing protein | - |
| STCNRZ1151_RS06930 (STCNRZ1151_06935) | - | 1323303..1323767 (-) | 465 | WP_011226345.1 | 8-oxo-dGTP diphosphatase | - |
| STCNRZ1151_RS06935 (STCNRZ1151_06940) | uvrB | 1323812..1325803 (-) | 1992 | WP_002953358.1 | excinuclease ABC subunit UvrB | - |
| STCNRZ1151_RS09535 (STCNRZ1151_06945) | - | 1326490..1327426 (-) | 937 | Protein_1304 | CPBP family intramembrane glutamic endopeptidase | - |
| STCNRZ1151_RS06950 (STCNRZ1151_06950) | - | 1327625..1329835 (+) | 2211 | WP_011226350.1 | ABC transporter substrate-binding protein/permease | - |
| STCNRZ1151_RS06955 (STCNRZ1151_06955) | - | 1329835..1330575 (+) | 741 | WP_002945131.1 | amino acid ABC transporter ATP-binding protein | - |
Sequence
Protein
Download Length: 623 a.a. Molecular weight: 67919.80 Da Isoelectric Point: 7.1310
>NTDB_id=510375 STCNRZ1151_RS06670 WP_011226292.1 1271059..1272930(-) (stkP/pknB) [Streptococcus thermophilus strain CNRZ1151]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMTDAKTLPKVDSVSSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFSTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPTAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAKEGEILS
QSSEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
YPQVGTAVDGTVILYVSVVTKSSSIQQSSTASTTQSPSSTSSSSESSTASSTETATEATHTEQ
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNESVAIKVLRTNYQTDQVAVARFQREARAMTELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKFIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPFDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHSRDSKVVFDDMTDAKTLPKVDSVSSVGPEKKISPKPSEPTPAP
SKQPREKASLSKKKKNLFSTLLKVLLGFVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKLESAGFKVGDVKEVEND
SVNKGKVIKTDPTAGTMRKEGASIDVYVSSGSKGFTLKNYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDNAKEGEILS
QSSEKNKSFNPKDSKAKIKFRVATPKTITMPDVTGLTVSTAVQTLNSKDISSSSIEYHDYNTGVKLDKSKVPSNTEVLYQ
YPQVGTAVDGTVILYVSVVTKSSSIQQSSTASTTQSPSSTSSSSESSTASSTETATEATHTEQ
Nucleotide
Download Length: 1872 bp
>NTDB_id=510375 STCNRZ1151_RS06670 WP_011226292.1 1271059..1272930(-) (stkP/pknB) [Streptococcus thermophilus strain CNRZ1151]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATGCTAAGACCC
TGCCAAAGGTTGATTCAGTTTCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTCAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAATGCGTAAAGAGGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATGTCGAAGACGATAATGCTAAAGAAGGCGAAATTCTATCT
CAAAGTTCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGTAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACCGAGGTCCTTTATCAA
TATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCACAGCAAGTACGACACAATCGCCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGCTACAGAAGCTACTCACACAGAGCAATAA
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAACGACCTGATTCTGGATAATGAAAGTGTAGCTATTAAGGTGCTACGTACCAATTATCAAACTGATCAGGTTG
CTGTGGCGCGTTTCCAGCGTGAAGCACGTGCCATGACTGAGCTTAGCCATCCGAATATCGTTGCGATTAGAGATATTGGT
GAAGAAGACGGTCAGCAGTTCTTGGTGATGGAGTATGTGGATGGTTCGGACTTGAAGAAATTCATTCAAGACCATGCACC
ATTGTCTAACCAAGATGTTGTGCGTATTATGGGGGAAGTCCTTTCCGCCATGACTCTTGCCCACCAAAAGGGTATTATTC
ACCGTGACCTTAAGCCACAGAACGTTCTATTAACTAAGGATGGTAGAGCTAAGGTTACAGACTTTGGTATCGCAGTAGCA
TTTGCTGAAACCAGCCTGACACAAACTAACTCAATGTTGGGGTCAGTCCATTATTTGTCACCAGAACAGGCACGTGGTTC
TAAAGCCACTATCCAAAGTGATATCTATGCTATGGGGATTATGCTCTTTGAAATGTTGACAGGGCATATCCCTTTTGATG
GCGATAGTGCAGTAACCATTGCACTTCAACATTTCCAAAAGCCCCTGCCATCGATTTTGGCTGAGAACCGTAACGTTCCT
CAAGCTTTAGAAAATGTTGTTATTAGAGCAACTGCTAAAAAGCTTGAAAATCGTTACAACAGCACTTTGGAAATGAGTCG
CGACCTAGTAACTAGTTTGCATCCTAGTCATAGTCGTGATTCTAAGGTAGTTTTTGATGACATGACGGATGCTAAGACCC
TGCCAAAGGTTGATTCAGTTTCATCAGTAGGTCCTGAGAAAAAGATTTCTCCTAAACCATCAGAGCCTACACCGGCTCCA
AGCAAACAACCGAGGGAAAAAGCTTCTCTATCTAAAAAAAAGAAAAATCTCTTTTCAACTCTACTCAAGGTTTTACTAGG
CTTCGTCTTTATAGGAATTATCATTTTTGCCTATCTTGTTTTTACCAATCCTGACAATGTCCAAGTACCAAATGTTGTAG
GTCAAGAGTTGTCAACAGCTCAGACGAAACTTGAAAGTGCAGGCTTTAAGGTTGGCGATGTTAAAGAAGTCGAAAATGAT
TCAGTCAATAAGGGCAAAGTTATCAAGACCGACCCTACAGCTGGGACAATGCGTAAAGAGGGAGCAAGCATTGATGTCTA
TGTTTCTTCTGGTAGCAAAGGTTTCACTCTGAAAAATTACAAGGGGAAAAATTATAAGGATGCCATTGAGGATTTAACCT
CGAATTATGGGGTTTCCGAGGATCAGATCGATATTCAACATGTCGAAGACGATAATGCTAAAGAAGGCGAAATTCTATCT
CAAAGTTCGGAGAAAAACAAGTCCTTCAATCCTAAAGATAGTAAGGCAAAAATCAAGTTTCGTGTGGCAACTCCTAAGAC
TATAACTATGCCTGATGTGACTGGTTTAACTGTCTCGACAGCAGTCCAAACCTTGAATAGTAAAGACATTTCAAGTAGCA
GTATTGAGTATCATGACTATAATACTGGTGTTAAGTTGGATAAGAGTAAGGTACCTAGTAATACCGAGGTCCTTTATCAA
TATCCTCAAGTTGGTACTGCTGTTGATGGCACAGTGATTCTCTATGTTTCAGTCGTAACTAAGAGTTCAAGTATTCAACA
GTCAAGCACAGCAAGTACGACACAATCGCCGTCATCTACAAGTTCTAGTTCTGAAAGTAGTACAGCTTCTAGTACCGAAA
CAGCTACAGAAGCTACTCACACAGAGCAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| stkP/pknB | Streptococcus salivarius strain HSISS4 |
90.361 |
93.258 |
0.843 |
| pknB | Streptococcus mutans UA159 |
64.522 |
87.319 |
0.563 |
| stkP | Streptococcus pneumoniae TIGR4 |
56.713 |
80.096 |
0.454 |
| stkP | Streptococcus pneumoniae D39 |
56.513 |
80.096 |
0.453 |
| stkP | Streptococcus pneumoniae R6 |
56.513 |
80.096 |
0.453 |
| stkP | Streptococcus pneumoniae Rx1 |
56.313 |
80.096 |
0.451 |