Detailed information NTG0510274

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: ST90730_RS08645
• Genome accession: NZ_CP065481
• Coordinates: 1657893..1658993 (-)
• Length: 366 a.a.
• NCBI ID: WP_148148900.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 90730
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1652893..1663993

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST90730_RS08605 (ST90730_08590)	-	1653505..1653702 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
ST90730_RS08610 (ST90730_08595)	-	1653951..1655144 (-)	1194	WP_022096898.1	acetate kinase	-
ST90730_RS08615 (ST90730_08600)	comYH	1655200..1656156 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST90730_RS08620 (ST90730_08605)	comGG	1656201..1656518 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
ST90730_RS08625 (ST90730_08610)	comYF	1656496..1656933 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST90730_RS08630 (ST90730_08615)	comGE	1656917..1657210 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST90730_RS08635 (ST90730_08620)	comYD	1657182..1657610 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST90730_RS08640 (ST90730_08625)	comYC	1657570..1657896 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST90730_RS08645 (ST90730_08630)	comYB	1657893..1658993 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST90730_RS08650 (ST90730_08635)	comGA/cglA/cilD	1658875..1659816 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
ST90730_RS08655 (ST90730_08640)	-	1659897..1660259 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41754.88 Da
• Isoelectric Point: 10.0449

>NTDB_id=510274 ST90730_RS08645 WP_148148900.1 1657893..1658993(-) (comYB) [Streptococcus thermophilus strain 90730]
MPEKISKTIRLPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKEASLSLM
KESLIRGDRLDQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=510274 ST90730_RS08645 WP_148148900.1 1657893..1658993(-) (comYB) [Streptococcus thermophilus strain 90730]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCTACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAGCATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGGATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCAGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGATATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.394	90.164	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.394	90.164	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413