Detailed information NTG0510271

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ST90730_RS08625
• Genome accession: NZ_CP065481
• Coordinates: 1656496..1656933 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 90730
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1651496..1661933

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST90730_RS08590 (ST90730_08575)	-	1651550..1652212 (-)	663	WP_011227583.1	type II CAAX endopeptidase family protein	-
ST90730_RS08595 (ST90730_08580)	-	1652315..1652763 (-)	449	Protein_1635	CAAX protease	-
ST90730_RS08600	-	1652837..1653262 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
ST90730_RS08605 (ST90730_08590)	-	1653505..1653702 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
ST90730_RS08610 (ST90730_08595)	-	1653951..1655144 (-)	1194	WP_022096898.1	acetate kinase	-
ST90730_RS08615 (ST90730_08600)	comYH	1655200..1656156 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST90730_RS08620 (ST90730_08605)	comGG	1656201..1656518 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
ST90730_RS08625 (ST90730_08610)	comYF	1656496..1656933 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST90730_RS08630 (ST90730_08615)	comGE	1656917..1657210 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST90730_RS08635 (ST90730_08620)	comYD	1657182..1657610 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST90730_RS08640 (ST90730_08625)	comYC	1657570..1657896 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST90730_RS08645 (ST90730_08630)	comYB	1657893..1658993 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST90730_RS08650 (ST90730_08635)	comGA/cglA/cilD	1658875..1659816 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
ST90730_RS08655 (ST90730_08640)	-	1659897..1660259 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=510271 ST90730_RS08625 WP_014608742.1 1656496..1656933(-) (comYF) [Streptococcus thermophilus strain 90730]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=510271 ST90730_RS08625 WP_014608742.1 1656496..1656933(-) (comYF) [Streptococcus thermophilus strain 90730]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441