Detailed information NTG0509976

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: ST4052_RS09285
• Genome accession: NZ_CP065476
• Coordinates: 1780614..1781849 (+)
• Length: 411 a.a.
• NCBI ID: WP_347100883.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4052
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1775614..1786849

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4052_RS09255 (ST4052_09365)	-	1776080..1778686 (+)	2607	WP_011226710.1	YfhO family protein	-
ST4052_RS09275 (ST4052_09385)	-	1779231..1779914 (-)	684	WP_011226711.1	YoaK family protein	-
ST4052_RS09280 (ST4052_09390)	rlmH	1779930..1780409 (-)	480	WP_011226712.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
ST4052_RS09285 (ST4052_09395)	htrA	1780614..1781849 (+)	1236	WP_347100883.1	trypsin-like peptidase domain-containing protein	Regulator
ST4052_RS09290 (ST4052_09400)	spo0J	1781915..1782682 (+)	768	WP_011226714.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42881.19 Da
• Isoelectric Point: 4.8401

>NTDB_id=509976 ST4052_RS09285 WP_347100883.1 1780614..1781849(+) (htrA) [Streptococcus thermophilus strain 4052]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTHIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=509976 ST4052_RS09285 WP_347100883.1 1780614..1781849(+) (htrA) [Streptococcus thermophilus strain 4052]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCATGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGAATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTCATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (307-402)

• Peptidase family M50 (Peptidase_M50) (4-406)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.538	98.054	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	57.039	100	0.572
htrA	Streptococcus mitis NCTC 12261	53.545	99.513	0.533
htrA	Streptococcus pneumoniae TIGR4	53.301	99.513	0.53
htrA	Streptococcus pneumoniae D39	53.301	99.513	0.53
htrA	Streptococcus pneumoniae Rx1	53.301	99.513	0.53
htrA	Streptococcus pneumoniae R6	53.301	99.513	0.53