Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   I5Z97_RS10495 Genome accession   NZ_CP065386
Coordinates   2144073..2145200 (+) Length   375 a.a.
NCBI ID   WP_196980249.1    Uniprot ID   -
Organism   Glaesserella parasuis strain LHDR_HPS_1_2     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2124834..2155825 2144073..2145200 within 0


Gene organization within MGE regions


Location: 2124834..2155825
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I5Z97_RS10360 (I5Z97_10345) - 2124834..2125181 (-) 348 WP_021111456.1 helix-turn-helix domain-containing protein -
  I5Z97_RS10365 (I5Z97_10350) - 2125360..2125593 (+) 234 WP_035496459.1 hypothetical protein -
  I5Z97_RS10370 (I5Z97_10355) selA 2125721..2127103 (-) 1383 WP_075630756.1 L-seryl-tRNA(Sec) selenium transferase -
  I5Z97_RS10380 (I5Z97_10365) - 2127569..2128828 (+) 1260 WP_075630755.1 tyrosine-type recombinase/integrase -
  I5Z97_RS10385 (I5Z97_10370) - 2129002..2129577 (+) 576 WP_075630754.1 Panacea domain-containing protein -
  I5Z97_RS10390 (I5Z97_10375) - 2129574..2130032 (+) 459 WP_075630753.1 hypothetical protein -
  I5Z97_RS10395 (I5Z97_10380) - 2130141..2130863 (+) 723 WP_075630752.1 hypothetical protein -
  I5Z97_RS10400 (I5Z97_10385) - 2131090..2131296 (+) 207 WP_075630751.1 helix-turn-helix transcriptional regulator -
  I5Z97_RS10405 (I5Z97_10390) - 2131313..2131702 (+) 390 WP_075630750.1 hypothetical protein -
  I5Z97_RS10410 (I5Z97_10395) - 2131686..2131988 (+) 303 WP_081378097.1 hypothetical protein -
  I5Z97_RS10415 (I5Z97_10400) - 2131978..2132451 (+) 474 WP_075630749.1 hypothetical protein -
  I5Z97_RS10420 (I5Z97_10405) - 2132439..2132876 (+) 438 WP_075630748.1 terminase small subunit -
  I5Z97_RS10425 (I5Z97_10410) - 2132930..2133685 (+) 756 WP_075630747.1 antA/AntB antirepressor family protein -
  I5Z97_RS10430 (I5Z97_10415) - 2133881..2134234 (+) 354 WP_075630746.1 hypothetical protein -
  I5Z97_RS10435 (I5Z97_10420) - 2134282..2135355 (+) 1074 WP_075630745.1 hypothetical protein -
  I5Z97_RS10440 (I5Z97_10425) - 2135670..2136116 (+) 447 WP_081378096.1 ash family protein -
  I5Z97_RS10445 (I5Z97_10430) - 2136109..2136318 (+) 210 WP_075630744.1 hypothetical protein -
  I5Z97_RS10450 (I5Z97_10435) - 2136320..2136628 (+) 309 WP_075630743.1 hypothetical protein -
  I5Z97_RS10455 (I5Z97_10440) - 2136621..2136956 (+) 336 WP_075630742.1 hypothetical protein -
  I5Z97_RS10460 (I5Z97_10445) - 2136953..2137360 (+) 408 WP_075630741.1 hypothetical protein -
  I5Z97_RS10465 (I5Z97_10450) - 2137344..2139530 (+) 2187 WP_075630740.1 DUF927 domain-containing protein -
  I5Z97_RS10470 (I5Z97_10455) - 2140153..2140428 (+) 276 WP_075630739.1 type II toxin-antitoxin system RelE family toxin -
  I5Z97_RS10475 (I5Z97_10460) - 2140467..2140847 (+) 381 WP_075630738.1 helix-turn-helix domain-containing protein -
  I5Z97_RS10480 (I5Z97_10465) - 2141494..2142435 (-) 942 WP_164692181.1 hypothetical protein -
  I5Z97_RS10485 (I5Z97_10470) rfaD 2142527..2143453 (-) 927 WP_021110191.1 ADP-glyceromanno-heptose 6-epimerase -
  I5Z97_RS10490 (I5Z97_10475) def 2143465..2143977 (-) 513 WP_005712670.1 peptide deformylase -
  I5Z97_RS10495 (I5Z97_10480) dprA 2144073..2145200 (+) 1128 WP_196980249.1 DNA-processing protein DprA Machinery gene
  I5Z97_RS10500 (I5Z97_10485) - 2145253..2146089 (+) 837 WP_196980250.1 heme/hemin ABC transporter substrate-binding protein -
  I5Z97_RS10505 (I5Z97_10490) - 2146089..2147075 (+) 987 WP_196980251.1 FecCD family ABC transporter permease -
  I5Z97_RS10510 (I5Z97_10495) - 2147075..2147863 (+) 789 WP_010787335.1 heme ABC transporter ATP-binding protein -
  I5Z97_RS11440 (I5Z97_10500) - 2148437..2153488 (+) 5052 WP_196980252.1 YadA-like family protein -
  I5Z97_RS11445 - 2153552..2153677 (-) 126 WP_021113336.1 hypothetical protein -
  I5Z97_RS10520 (I5Z97_10505) rpoH 2153918..2154865 (-) 948 WP_005711000.1 RNA polymerase sigma factor RpoH -
  I5Z97_RS10525 (I5Z97_10510) xerC 2154923..2155825 (-) 903 WP_080513250.1 tyrosine recombinase XerC -

Sequence

Protein


Download         Length: 375 a.a.        Molecular weight: 41722.67 Da        Isoelectric Point: 5.3954

>NTDB_id=509141 I5Z97_RS10495 WP_196980249.1 2144073..2145200(+) (dprA) [Glaesserella parasuis strain LHDR_HPS_1_2]
MTHLTKLLALLQVPQLGAQRIGRLLSEVDFGEFCQYDKTALKQMGWNERQIQHWFNPEHKWIDQALQWAEQDQQRILTLF
DEDYPFLLKQISTAPPVLFVRGNVESLSLPQIAIVGSRDYSHYGEHWAGHFSAELVKHQLAVTSGLAIGIDGFCHQRAAN
ENGITIAVLGSGLDQVYPARHKKLAEQIVETSGALVSEFFPSQPPIAENFPRRNRIISGLSLGTLVIEATVNSGSLITAR
YALEQGREVFALPNSVQNPYSEGCHKLIKEGALLVENIDDILEAIAWQRQSVHIQPSLFDTKPKQAVKSDPKFAKNLPEL
TACQQQLFEQISLEPISIDDLAKATDMAVETALIELLNLELLGVVKQVSGGYVIT

Nucleotide


Download         Length: 1128 bp        

>NTDB_id=509141 I5Z97_RS10495 WP_196980249.1 2144073..2145200(+) (dprA) [Glaesserella parasuis strain LHDR_HPS_1_2]
ATGACACATCTCACAAAATTATTAGCCCTGTTACAAGTGCCACAGCTTGGCGCGCAACGTATCGGGCGGTTACTCTCGGA
AGTGGACTTTGGCGAATTTTGTCAATATGACAAAACCGCATTAAAGCAAATGGGCTGGAATGAACGGCAAATTCAGCACT
GGTTTAATCCTGAGCATAAATGGATCGATCAGGCATTGCAATGGGCGGAACAGGATCAGCAACGGATTTTAACCTTATTT
GACGAAGATTATCCTTTTTTATTGAAGCAGATCAGTACTGCTCCCCCTGTGCTTTTTGTGCGTGGGAATGTTGAAAGTTT
ATCGTTACCGCAGATAGCTATCGTCGGCAGTCGAGATTATTCCCACTATGGCGAACACTGGGCAGGGCATTTTTCGGCGG
AATTAGTGAAACATCAACTTGCTGTCACTAGTGGTTTAGCCATAGGCATAGACGGATTTTGTCATCAGCGTGCGGCCAAT
GAAAACGGGATTACTATTGCGGTTTTAGGCAGTGGTTTAGACCAAGTTTACCCTGCTCGCCATAAAAAACTTGCTGAACA
AATCGTTGAAACAAGCGGTGCGTTAGTGTCGGAATTTTTCCCTAGCCAGCCACCGATTGCTGAAAATTTCCCTAGACGAA
ATCGCATCATCAGCGGATTATCTCTCGGCACATTGGTTATTGAAGCCACGGTGAACAGTGGCTCGCTCATCACTGCTCGT
TATGCGTTAGAGCAAGGACGAGAAGTTTTTGCATTGCCGAACTCAGTACAAAACCCGTATAGCGAAGGGTGCCATAAATT
GATTAAAGAAGGGGCATTACTGGTTGAAAATATTGACGACATTTTAGAAGCGATTGCGTGGCAACGGCAATCAGTGCATA
TTCAACCAAGTCTGTTTGATACGAAACCTAAACAAGCGGTGAAATCCGACCCCAAATTTGCAAAAAATCTACCTGAACTG
ACCGCTTGTCAGCAACAATTGTTTGAACAGATTAGCCTTGAGCCGATCAGCATTGATGATCTTGCCAAAGCGACGGATAT
GGCGGTAGAAACTGCATTGATTGAGCTGCTGAATTTGGAGTTGTTGGGCGTAGTGAAGCAGGTGAGTGGGGGGTATGTAA
TCACTTGA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(69-276)

DprA winged helix domain (DprA_WH)

(313-371)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Glaesserella parasuis strain SC1401

98.133

100

0.981
  dprA Haemophilus influenzae Rd KW20

53.235

90.667

0.483
  dprA Vibrio campbellii strain DS40M4

47.185

99.467

0.469
  dprA Vibrio cholerae strain A1552

44.415

100

0.445
  dprA Legionella pneumophila strain ERS1305867

39.418

100

0.397
  dprA Neisseria gonorrhoeae MS11

43.631

83.733

0.365