Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I2439_RS08945 Genome accession   NZ_CP065191
Coordinates   1869429..1870193 (-) Length   254 a.a.
NCBI ID   WP_012677379.1    Uniprot ID   A0AAW3GKI0
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ46     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1864429..1875193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2439_RS08925 (HIEAAJJG_01806) - 1864762..1865988 (-) 1227 WP_111678556.1 cysteine desulfurase -
  I2439_RS08930 (HIEAAJJG_01807) sufD 1866015..1867277 (-) 1263 WP_111678558.1 Fe-S cluster assembly protein SufD -
  I2439_RS08935 (HIEAAJJG_01808) sufC 1867368..1868138 (-) 771 WP_012516290.1 Fe-S cluster assembly ATPase SufC -
  I2439_RS08940 (HIEAAJJG_01809) - 1868265..1869422 (-) 1158 WP_111678863.1 MraY family glycosyltransferase -
  I2439_RS08945 (HIEAAJJG_01810) mecA 1869429..1870193 (-) 765 WP_012677379.1 adaptor protein MecA Regulator
  I2439_RS08950 (HIEAAJJG_01811) - 1870313..1871152 (-) 840 WP_012680101.1 undecaprenyl-diphosphate phosphatase -
  I2439_RS08955 (HIEAAJJG_01812) - 1871468..1873036 (+) 1569 WP_012516295.1 ABC transporter substrate-binding protein/permease -
  I2439_RS08960 (HIEAAJJG_01813) - 1873029..1873769 (+) 741 WP_111678559.1 amino acid ABC transporter ATP-binding protein -
  I2439_RS08965 (HIEAAJJG_01814) - 1874096..1874212 (+) 117 WP_111678561.1 putative metal homeostasis protein -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29250.07 Da        Isoelectric Point: 4.2228

>NTDB_id=507850 I2439_RS08945 WP_012677379.1 1869429..1870193(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHASPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=507850 I2439_RS08945 WP_012677379.1 1869429..1870193(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGGATGGAGCT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTCATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACTCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAATCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCCCAGATGACTCCAGAGGATTTTTTCAGAAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTCAATGCCCATGAAAAGCTTGAAAAAATCGAGGAGATCATGGAGGACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAGTAAGGAAGCTGCTGAGCTTGATGAGCCGACGGAGCCACTTGATTATGTT
CACTATGTTCTTGATTTTGCTTCTGTTCGAGACGCTGTTTGCTTTGCTAAGGTGATTGATTTTCCGATCGAGGCTTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACGATTTTACTTGATGTGCAAAACAAGCCTGCCTACTTTGCCAACGTGA
TGTATGCCAGATTGATTGAGCATGCTAGTCCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTGCAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.745

98.819

0.63
  mecA Streptococcus thermophilus LMD-9

57.255

100

0.575
  mecA Streptococcus thermophilus LMG 18311

56.471

100

0.567
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476