Detailed information NTG0507837

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: I2439_RS08000
• Genome accession: NZ_CP065191
• Coordinates: 1683069..1685225 (+)
• Length: 718 a.a.
• NCBI ID: WP_111678343.1
• Uniprot ID: A0AAJ1PLU2
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ46
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1678069..1690225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2439_RS10500	-	1678553..1678678 (-)	126	WP_255313937.1	hypothetical protein	-
I2439_RS07965	-	1679201..1679386 (+)	186	WP_255313988.1	helix-turn-helix transcriptional regulator	-
I2439_RS07970 (HIEAAJJG_01617)	-	1679488..1680069 (-)	582	WP_043031274.1	GNAT family N-acetyltransferase	-
I2439_RS07975 (HIEAAJJG_01618)	-	1680320..1680733 (-)	414	WP_021321055.1	hypothetical protein	-
I2439_RS07980 (HIEAAJJG_01619)	-	1681016..1681312 (-)	297	WP_111678339.1	bacteriocin immunity protein	-
I2439_RS07985	-	1681312..1681500 (-)	189	WP_229297300.1	leucocin A/sakacin P family class II bacteriocin	-
I2439_RS07990 (HIEAAJJG_01620)	-	1682259..1682555 (-)	297	WP_111678854.1	bacteriocin immunity protein	-
I2439_RS07995 (HIEAAJJG_01621)	-	1682562..1682810 (-)	249	WP_111678341.1	garvicin Q family class II bacteriocin	-
I2439_RS08000 (HIEAAJJG_01622)	comA/nlmT	1683069..1685225 (+)	2157	WP_111678343.1	peptide cleavage/export ABC transporter	Regulator
I2439_RS08005 (HIEAAJJG_01623)	-	1685236..1686594 (+)	1359	WP_111678345.1	bacteriocin secretion accessory protein	-
I2439_RS08010 (HIEAAJJG_01624)	-	1686694..1686828 (+)	135	WP_012516117.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
I2439_RS10535 (HIEAAJJG_01625)	-	1686947..1688281 (-)	1335	WP_111678347.1	GHKL domain-containing protein	-
I2439_RS08020 (HIEAAJJG_01626)	comE/blpR	1688281..1689030 (-)	750	WP_111678349.1	response regulator transcription factor	Regulator
I2439_RS08025 (HIEAAJJG_01627)	-	1689662..1689865 (-)	204	WP_111678351.1	TmhB bacteriocin enhancer peptide	-
I2439_RS08030 (HIEAAJJG_01628)	-	1689882..1690139 (-)	258	WP_111678353.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 718 a.a.
• Molecular weight: 80585.75 Da
• Isoelectric Point: 7.7847

>NTDB_id=507837 I2439_RS08000 WP_111678343.1 1683069..1685225(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAHLRELAKTNKEGTTALGIVMAAKEIGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINIAGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFRLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGRISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYVFNGSILENLTLGAKQGISQEDILKACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide

• Length: 2157 bp

>NTDB_id=507837 I2439_RS08000 WP_111678343.1 1683069..1685225(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
ATGACACTCTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCTTCGATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTCATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATAGGGTTTGAAACCAGACCCATTCAAGCGGATATGACCCTCTTTGACATGGCAGAT
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGTCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCA
CTTATTTTTAAACAGCGAGCCCTTATTTTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTGCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAACTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCTCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGTTATCTCTGATTTCTATCCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTCGATAAGTCCTTTAGGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTTATTAATGGTAGGATTTCAATCGGGCAGTTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAACAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAGCCTTATAAGGGACGTATAACCATCAACCAAAATGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATGTCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAGGGCAT
CAGCCAGGAAGACATTCTTAAAGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTGGTTCTTAATCAAG
GGCAAATCATTGAAACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (169-439)

• Peptidase C39 family (Peptidase_C39) (8-143)

• ABC transporter (ABC_tran) (501-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	70.99	99.861	0.709
comA	Streptococcus mitis SK321	67.882	99.304	0.674
comA	Streptococcus mitis NCTC 12261	67.602	99.304	0.671
comA	Streptococcus pneumoniae D39	67.181	99.304	0.667
comA	Streptococcus pneumoniae Rx1	67.181	99.304	0.667
comA	Streptococcus pneumoniae R6	67.181	99.304	0.667
comA	Streptococcus pneumoniae TIGR4	66.9	99.304	0.664
comA	Streptococcus gordonii str. Challis substr. CH1	65.358	99.304	0.649