Detailed information NTG0507764

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: I2438_RS05070
• Genome accession: NZ_CP065190
• Coordinates: 1030900..1031574 (+)
• Length: 224 a.a.
• NCBI ID: WP_021320708.1
• Uniprot ID: A0AAW3GMV5
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ36
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1025900..1036574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2438_RS05055 (HCFMJIKG_00995)	pstB	1026227..1026985 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
I2438_RS05060 (HCFMJIKG_00996)	phoU	1027056..1027709 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
I2438_RS05065 (HCFMJIKG_00997)	-	1027944..1030481 (+)	2538	WP_231146263.1	M1 family metallopeptidase	-
I2438_RS05070 (HCFMJIKG_00998)	ciaR	1030900..1031574 (+)	675	WP_021320708.1	response regulator transcription factor	Regulator
I2438_RS05075 (HCFMJIKG_00999)	ciaH	1031567..1032877 (+)	1311	WP_014622812.1	sensor histidine kinase	Regulator
I2438_RS05080 (HCFMJIKG_01000)	-	1033262..1033654 (+)	393	WP_024273227.1	hypothetical protein	-
I2438_RS05085 (HCFMJIKG_01001)	-	1033823..1034149 (+)	327	WP_014623416.1	hypothetical protein	-
I2438_RS10525	-	1034181..1034383 (+)	203	Protein_976	hypothetical protein	-
I2438_RS05090 (HCFMJIKG_01002)	-	1034429..1034830 (+)	402	WP_042670593.1	hypothetical protein	-
I2438_RS05095 (HCFMJIKG_01003)	-	1034832..1035077 (+)	246	WP_021320712.1	hypothetical protein	-
I2438_RS05100 (HCFMJIKG_01004)	-	1035093..1035500 (+)	408	WP_014622815.1	hypothetical protein	-
I2438_RS05105 (HCFMJIKG_01005)	-	1035510..1035800 (+)	291	WP_021320713.1	hypothetical protein	-
I2438_RS05110 (HCFMJIKG_01006)	-	1035724..1036107 (+)	384	WP_231146262.1	hypothetical protein	-
I2438_RS05115 (HCFMJIKG_01007)	-	1036109..1036360 (+)	252	WP_012678012.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25569.58 Da
• Isoelectric Point: 4.5644

>NTDB_id=507764 I2438_RS05070 WP_021320708.1 1030900..1031574(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=507764 I2438_RS05070 WP_021320708.1 1030900..1031574(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae D39	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae R6	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae TIGR4	80.543	98.661	0.795
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.865	100	0.397