Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I2438_RS05075 Genome accession   NZ_CP065190
Coordinates   1031567..1032877 (+) Length   436 a.a.
NCBI ID   WP_014622812.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ36     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1026567..1037877
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2438_RS05060 (HCFMJIKG_00996) phoU 1027056..1027709 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  I2438_RS05065 (HCFMJIKG_00997) - 1027944..1030481 (+) 2538 WP_231146263.1 M1 family metallopeptidase -
  I2438_RS05070 (HCFMJIKG_00998) ciaR 1030900..1031574 (+) 675 WP_021320708.1 response regulator transcription factor Regulator
  I2438_RS05075 (HCFMJIKG_00999) ciaH 1031567..1032877 (+) 1311 WP_014622812.1 sensor histidine kinase Regulator
  I2438_RS05080 (HCFMJIKG_01000) - 1033262..1033654 (+) 393 WP_024273227.1 hypothetical protein -
  I2438_RS05085 (HCFMJIKG_01001) - 1033823..1034149 (+) 327 WP_014623416.1 hypothetical protein -
  I2438_RS10525 - 1034181..1034383 (+) 203 Protein_976 hypothetical protein -
  I2438_RS05090 (HCFMJIKG_01002) - 1034429..1034830 (+) 402 WP_042670593.1 hypothetical protein -
  I2438_RS05095 (HCFMJIKG_01003) - 1034832..1035077 (+) 246 WP_021320712.1 hypothetical protein -
  I2438_RS05100 (HCFMJIKG_01004) - 1035093..1035500 (+) 408 WP_014622815.1 hypothetical protein -
  I2438_RS05105 (HCFMJIKG_01005) - 1035510..1035800 (+) 291 WP_021320713.1 hypothetical protein -
  I2438_RS05110 (HCFMJIKG_01006) - 1035724..1036107 (+) 384 WP_231146262.1 hypothetical protein -
  I2438_RS05115 (HCFMJIKG_01007) - 1036109..1036360 (+) 252 WP_012678012.1 hypothetical protein -
  I2438_RS05120 (HCFMJIKG_01008) - 1036536..1036916 (+) 381 WP_042670594.1 hypothetical protein -
  I2438_RS05125 (HCFMJIKG_01009) - 1036913..1037173 (+) 261 WP_021320716.1 hypothetical protein -
  I2438_RS05130 (HCFMJIKG_01010) - 1037189..1037602 (+) 414 WP_037584321.1 hypothetical protein -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49604.24 Da        Isoelectric Point: 9.6507

>NTDB_id=507765 I2438_RS05075 WP_014622812.1 1031567..1032877(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MNKLKKGLLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILDNSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGTIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=507765 I2438_RS05075 WP_014622812.1 1031567..1032877(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGAATAAACTAAAAAAAGGATTATTGTCCGATAATTATACGCATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACCATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCTAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAACTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCTAA
TGGGACGATATTGAACTCCTTTGACGCTTTCTCTAATTACCAAAGCTTTCGTTTAGACAAAAGCCAGCTCAATAACATTG
TCACAACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACTGTTAAGGTTCACATTAAAAACTAT
CCAGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAGCTGGATACTGCTAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTGGCCAGTATTTATTTGGCTAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGGACTCCTTTAGCGGTGCTGCAAAATCGT
TTGGAATCGCTGTTTAGAAAGCCTAACGAAACCATTTTAGACAATAGCGAGCATATTGCGTCAAGCCTAGATGAGGTTCG
TAATATGAGAATATTAACAACTAATCTGTTAAATTTAGCCAGACGTGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAGTCAGGCAAGCAGTTTATCTCAGCTAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGTGATAATAAGCC
TACCGGTACCATATTTGAAGTAAAATTATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.606

100

0.516
  ciaH Streptococcus pneumoniae D39

51.606

100

0.516
  ciaH Streptococcus pneumoniae R6

51.606

100

0.516
  ciaH Streptococcus pneumoniae TIGR4

51.606

100

0.516