Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   VB13_RS00670 Genome accession   NZ_CP077685
Coordinates   104228..104656 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain M49 591     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99228..109656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VB13_RS00650 (VB13_00680) - 101559..101924 (+) 366 WP_002986560.1 DUF1033 family protein -
  VB13_RS00655 (VB13_00685) comGA 102017..102955 (+) 939 WP_009880361.1 competence type IV pilus ATPase ComGA Machinery gene
  VB13_RS00660 (VB13_00690) comGB 102891..103925 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  VB13_RS00665 (VB13_00695) comGC 103927..104253 (+) 327 WP_012560386.1 competence type IV pilus major pilin ComGC Machinery gene
  VB13_RS00670 (VB13_00700) comGD 104228..104656 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  VB13_RS00675 (VB13_00705) comGE 104613..104897 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE Machinery gene
  VB13_RS00680 (VB13_00710) comGF 104890..105324 (+) 435 WP_009880359.1 competence type IV pilus minor pilin ComGF Machinery gene
  VB13_RS00685 (VB13_00715) comGG 105308..105634 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  VB13_RS00690 (VB13_00720) comGH 105732..106685 (+) 954 WP_009880357.1 class I SAM-dependent methyltransferase Machinery gene
  VB13_RS00695 (VB13_00725) - 106744..107940 (+) 1197 WP_009880356.1 acetate kinase -
  VB13_RS00700 - 108126..108434 (+) 309 Protein_88 hypothetical protein -
  VB13_RS00705 (VB13_00730) proC 108517..109287 (-) 771 WP_009880354.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=506830 VB13_RS00670 WP_002986548.1 104228..104656(+) (comGD) [Streptococcus pyogenes strain M49 591]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=506830 VB13_RS00670 WP_002986548.1 104228..104656(+) (comGD) [Streptococcus pyogenes strain M49 591]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366