Detailed information
Bioinformatically predicted
Overview
| Name | comGH | Type | Machinery gene |
| Locus tag | VB13_RS00690 | Genome accession | NZ_CP077685 |
| Coordinates | 105732..106685 (+) | Length | 317 a.a. |
| NCBI ID | WP_009880357.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain M49 591 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 100732..111685
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| VB13_RS00650 (VB13_00680) | - | 101559..101924 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| VB13_RS00655 (VB13_00685) | comGA | 102017..102955 (+) | 939 | WP_009880361.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| VB13_RS00660 (VB13_00690) | comGB | 102891..103925 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| VB13_RS00665 (VB13_00695) | comGC | 103927..104253 (+) | 327 | WP_012560386.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| VB13_RS00670 (VB13_00700) | comGD | 104228..104656 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| VB13_RS00675 (VB13_00705) | comGE | 104613..104897 (+) | 285 | WP_011284422.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| VB13_RS00680 (VB13_00710) | comGF | 104890..105324 (+) | 435 | WP_009880359.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| VB13_RS00685 (VB13_00715) | comGG | 105308..105634 (+) | 327 | WP_009880358.1 | competence type IV pilus minor pilin ComGG | - |
| VB13_RS00690 (VB13_00720) | comGH | 105732..106685 (+) | 954 | WP_009880357.1 | class I SAM-dependent methyltransferase | Machinery gene |
| VB13_RS00695 (VB13_00725) | - | 106744..107940 (+) | 1197 | WP_009880356.1 | acetate kinase | - |
| VB13_RS00700 | - | 108126..108434 (+) | 309 | Protein_88 | hypothetical protein | - |
| VB13_RS00705 (VB13_00730) | proC | 108517..109287 (-) | 771 | WP_009880354.1 | pyrroline-5-carboxylate reductase | - |
| VB13_RS00710 (VB13_00735) | pepA | 109335..110402 (-) | 1068 | WP_012560390.1 | glutamyl aminopeptidase | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35995.11 Da Isoelectric Point: 4.7205
>NTDB_id=506833 VB13_RS00690 WP_009880357.1 105732..106685(+) (comGH) [Streptococcus pyogenes strain M49 591]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDPIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDPIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=506833 VB13_RS00690 WP_009880357.1 105732..106685(+) (comGH) [Streptococcus pyogenes strain M49 591]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATCCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATCCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGH | Streptococcus mutans UA159 |
66.139 |
99.685 |
0.659 |
| comGH | Streptococcus mutans UA140 |
65.823 |
99.685 |
0.656 |