Detailed information NTG0506617

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: I2437_RS07140
• Genome accession: NZ_CP065061
• Coordinates: 1510902..1513055 (-)
• Length: 717 a.a.
• NCBI ID: WP_115267067.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ33
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 1505902..1518055

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2437_RS07120 (IEMOCGPF_01422)	nrdI	1506896..1507303 (-)	408	WP_164437676.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
I2437_RS07125 (IEMOCGPF_01423)	nrdF	1507305..1508318 (-)	1014	WP_043040212.1	class 1b ribonucleoside-diphosphate reductase subunit beta	-
I2437_RS07130 (IEMOCGPF_01424)	-	1508775..1509011 (-)	237	WP_024273149.1	hypothetical protein	-
I2437_RS07135 (IEMOCGPF_01425)	comB	1509520..1510887 (-)	1368	WP_012515170.1	bacteriocin secretion accessory protein	Regulator
I2437_RS07140 (IEMOCGPF_01426)	comA	1510902..1513055 (-)	2154	WP_115267067.1	peptide cleavage/export ABC transporter ComA	Regulator
I2437_RS07145 (IEMOCGPF_01427)	-	1513282..1513449 (-)	168	WP_012515168.1	class IIb bacteriocin, lactobin A/cerein 7B family	-
I2437_RS07150 (IEMOCGPF_01428)	-	1513472..1513618 (-)	147	WP_021320464.1	hypothetical protein	-
I2437_RS07155 (IEMOCGPF_01429)	-	1513632..1513790 (-)	159	WP_021320463.1	hypothetical protein	-
I2437_RS07160 (IEMOCGPF_01430)	-	1513903..1514043 (-)	141	WP_012515166.1	hypothetical protein	-
I2437_RS07165 (IEMOCGPF_01432)	-	1514395..1515288 (-)	894	WP_206157771.1	XRE family transcriptional regulator	-
I2437_RS07170 (IEMOCGPF_01433)	metG	1515846..1517849 (-)	2004	WP_115267069.1	methionine--tRNA ligase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80511.44 Da
• Isoelectric Point: 9.0606

>NTDB_id=506617 I2437_RS07140 WP_115267067.1 1510902..1513055(-) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MKFRRKHYRAQVDTRDCGVASLAMIYGYYGSYYSLATLREAAKTTQEGTTAFGLVKVSEALGFETRAIRADMSLFDVEGL
SYPFIAHVLKKGKFLHYYVVTGQDKKYIHIADPDPTVKLTCLSRQRFASEWTGVTIFIAPTPEYKPHKEKKNSLLDFVPL
LAKQKGLITNIVVATLLVTIINIIGSYYLQSIIDTYVPSVMKNTLGIISVGLVIVYALQQVISYAQEYLLLILGQRLSID
VILSYIKHIFNLPMSFFATRRTGEIVSRFNDANSIIDALASTILSIFLDVSVIVIISLVLFSQNVNLFVISLLALPIYAV
IIFAFMKPFERMNQETMEANSIMSSSIIEDINGIETIKSLTSEKIRYQKIDKEFVAYLKKSFNYSRAESQQRALKKVAQL
ILNVSILWIGANLVMDGKMSLGQLITYNSLLIYFTNPLENIINLQTKLQTAQVANNRLNEVYLVESEFSEKKNVQDLSLT
SGDIKFNDVSYRYGYGKDVLSEINLHIKRGSKVAFVGISGSGKTTLAKMIVSFFEPSKGEISLNNVNLNQIDKHALRQHI
NYLPQQPYVFNGTILENLLLGAREGTTQEDIMKAVELAEIKSDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDS
PVLILDEATSNLDILTEKRIVDNLMALDKTLIFIAHRLTITERTEHVVVLDKGKIIEQGTHRDLVSQNGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=506617 I2437_RS07140 WP_115267067.1 1510902..1513055(-) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGAAATTTAGAAGAAAACACTACCGTGCTCAGGTTGATACTCGCGATTGTGGTGTAGCTTCTCTGGCCATGATTTACGG
TTATTATGGATCGTATTATTCGCTAGCAACGTTACGTGAAGCTGCAAAGACAACGCAGGAAGGGACTACAGCTTTTGGTT
TAGTCAAAGTTTCTGAGGCGCTTGGGTTTGAAACGAGAGCTATTAGGGCTGACATGAGTTTATTTGATGTGGAAGGATTA
TCTTATCCTTTTATTGCCCATGTTCTAAAAAAAGGTAAGTTCCTTCATTATTATGTGGTAACAGGACAAGATAAAAAATA
TATTCATATTGCAGATCCAGATCCAACTGTAAAGTTGACTTGTCTTTCTCGTCAGCGATTTGCTTCAGAGTGGACAGGTG
TGACAATTTTTATCGCTCCTACTCCTGAATACAAACCTCACAAGGAAAAGAAAAATAGTCTGCTAGATTTTGTGCCTCTC
CTAGCAAAGCAAAAAGGATTGATTACTAATATCGTTGTGGCAACGCTTTTGGTAACGATTATCAATATTATTGGTTCGTA
TTATCTTCAATCAATCATTGATACCTATGTTCCTAGTGTGATGAAGAATACACTAGGTATTATTTCCGTAGGTTTGGTTA
TTGTCTATGCCCTTCAACAAGTGATCTCATATGCGCAAGAGTATTTATTGCTGATATTAGGGCAACGTTTATCTATTGAT
GTAATTCTTTCTTATATCAAACATATTTTCAACCTTCCTATGTCTTTTTTCGCGACGAGAAGGACCGGGGAAATTGTTTC
TCGTTTTAATGATGCTAATTCAATCATTGATGCTTTAGCAAGTACAATTTTATCTATTTTCCTTGATGTTTCTGTCATTG
TAATTATATCTCTTGTTCTTTTTTCGCAGAATGTAAATCTATTTGTTATCAGTTTGCTTGCTCTGCCTATCTATGCAGTG
ATTATCTTTGCCTTCATGAAGCCATTTGAACGGATGAATCAAGAGACAATGGAAGCAAATTCAATCATGTCATCTTCTAT
TATTGAAGATATAAACGGTATTGAGACTATTAAATCATTAACTAGCGAAAAGATAAGATACCAAAAAATAGATAAAGAAT
TTGTAGCTTATCTTAAGAAATCTTTCAACTATAGTAGGGCAGAAAGCCAACAACGAGCATTGAAAAAAGTAGCTCAGCTT
ATCCTAAACGTGAGCATACTCTGGATAGGAGCCAATCTGGTTATGGACGGAAAAATGAGTTTAGGTCAACTGATTACCTA
TAACTCTCTCCTAATCTACTTTACAAATCCTCTGGAGAATATTATCAATCTTCAAACGAAACTTCAAACCGCTCAAGTCG
CTAATAATCGATTGAATGAGGTATATCTAGTTGAATCCGAGTTCTCTGAAAAGAAGAATGTTCAAGACTTATCTTTGACC
TCTGGTGACATAAAATTCAATGATGTTAGCTATCGATATGGATATGGAAAAGATGTTTTATCAGAAATAAATTTGCATAT
TAAACGAGGAAGCAAGGTTGCTTTTGTTGGGATTTCAGGTTCTGGAAAAACGACTTTAGCTAAGATGATTGTCAGTTTCT
TTGAACCAAGCAAAGGCGAAATATCATTAAATAATGTGAATCTAAATCAAATTGACAAACATGCTCTTCGCCAGCACATT
AACTATCTTCCTCAACAACCTTACGTATTTAATGGGACAATCCTTGAGAATTTACTTCTTGGAGCACGTGAAGGGACGAC
TCAAGAAGACATTATGAAGGCAGTAGAATTGGCTGAAATCAAGTCTGATATTGAACGTATGCCTTTGAATTATCAAACAG
AGTTAACCTCAGATGGTGCAGGGATTTCTGGAGGTCAACGTCAACGTATTGCCTTAGCAAGGGCATTATTGACAGATTCT
CCTGTTTTGATATTAGACGAAGCTACAAGTAACTTGGATATTTTGACTGAGAAGCGAATTGTTGATAACCTGATGGCTTT
AGATAAAACCTTGATATTTATTGCTCACCGTTTAACTATTACAGAGCGTACAGAGCATGTCGTCGTTTTGGATAAAGGAA
AGATCATAGAGCAAGGAACACACAGAGACCTTGTTTCTCAGAATGGCTTTTATGCTCACTTGGTCAATAGTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (500-650)

• ABC transporter transmembrane region (ABC_membrane) (169-438)

• Peptidase C39 family (Peptidase_C39) (6-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	82.008	100	0.82
comA	Streptococcus mitis SK321	81.59	100	0.816
comA	Streptococcus pneumoniae Rx1	81.59	100	0.816
comA	Streptococcus pneumoniae D39	81.59	100	0.816
comA	Streptococcus pneumoniae R6	81.59	100	0.816
comA	Streptococcus pneumoniae TIGR4	81.311	100	0.813
comA	Streptococcus gordonii str. Challis substr. CH1	78.522	100	0.785
comA/nlmT	Streptococcus mutans UA159	62.901	100	0.629