Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I2437_RS01410 Genome accession   NZ_CP065061
Coordinates   268453..269217 (+) Length   254 a.a.
NCBI ID   WP_043039426.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ33     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 263453..274217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2437_RS01390 (IEMOCGPF_00275) - 264438..264554 (-) 117 WP_012677375.1 putative metal homeostasis protein -
  I2437_RS01395 (IEMOCGPF_00276) - 264877..265617 (-) 741 WP_012680102.1 amino acid ABC transporter ATP-binding protein -
  I2437_RS01400 (IEMOCGPF_00277) - 265610..267178 (-) 1569 WP_206157902.1 ABC transporter substrate-binding protein/permease -
  I2437_RS01405 (IEMOCGPF_00278) - 267494..268333 (+) 840 WP_012677378.1 undecaprenyl-diphosphate phosphatase -
  I2437_RS01410 (IEMOCGPF_00279) mecA 268453..269217 (+) 765 WP_043039426.1 adaptor protein MecA Regulator
  I2437_RS01415 (IEMOCGPF_00280) - 269224..270381 (+) 1158 WP_043041121.1 MraY family glycosyltransferase -
  I2437_RS01420 (IEMOCGPF_00281) sufC 270502..271272 (+) 771 WP_014623470.1 Fe-S cluster assembly ATPase SufC -
  I2437_RS01425 (IEMOCGPF_00282) sufD 271364..272626 (+) 1263 WP_014623469.1 Fe-S cluster assembly protein SufD -
  I2437_RS01430 (IEMOCGPF_00283) - 272653..273879 (+) 1227 WP_206157903.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29262.08 Da        Isoelectric Point: 4.2497

>NTDB_id=506581 I2437_RS01410 WP_043039426.1 268453..269217(+) (mecA) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMENVVDATLAEQADNKEAAELEEPTEPLDYV
HYVLDFASVRDAVCFAKAIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHASPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=506581 I2437_RS01410 WP_043039426.1 268453..269217(+) (mecA) [Streptococcus equi subsp. zooepidemicus strain SEZ33]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGGATGGAGCT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTCATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACTCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAGTCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGGAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTTAATGCCCATGAAAAGCTCGAAAAAATTGAGGAGATCATGGAGAACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAATAAGGAAGCTGCTGAGCTTGAAGAGCCGACAGAGCCACTTGATTACGTT
CACTATGTTCTTGATTTTGCTTCTGTGCGAGACGCTGTTTGCTTTGCTAAGGCGATTGATTTTCCGATCGAGGCCTCTGA
ATTGTATAAGGGTCCTCGTCATTATCATATGACAATCTTACTTGATGTGCAAAACAAGCCTGCCTACTTTGCCAATGTGA
TGTATGCCAGATTGATTGAGCATGCTAGTCCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTGCAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.745

98.819

0.63
  mecA Streptococcus thermophilus LMD-9

56.471

100

0.567
  mecA Streptococcus thermophilus LMG 18311

55.686

100

0.559
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476