Detailed information NTG0506542

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: I2436_RS04600
• Genome accession: NZ_CP065060
• Coordinates: 979386..980060 (+)
• Length: 224 a.a.
• NCBI ID: WP_021320708.1
• Uniprot ID: A0AAW3GMV5
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ28
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 974386..985060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2436_RS04585 (GDAKBCAL_00913)	pstB	974714..975472 (+)	759	WP_012678019.1	phosphate ABC transporter ATP-binding protein PstB	-
I2436_RS04590 (GDAKBCAL_00914)	phoU	975543..976196 (+)	654	WP_012678018.1	phosphate signaling complex protein PhoU	-
I2436_RS04595 (GDAKBCAL_00915)	-	976430..978967 (+)	2538	WP_206153189.1	M1 family metallopeptidase	-
I2436_RS04600 (GDAKBCAL_00916)	ciaR	979386..980060 (+)	675	WP_021320708.1	response regulator	Regulator
I2436_RS04605 (GDAKBCAL_00917)	ciaH	980053..981363 (+)	1311	WP_014622812.1	HAMP domain-containing sensor histidine kinase	Regulator
I2436_RS04610 (GDAKBCAL_00918)	-	981748..982137 (+)	390	WP_206153191.1	hypothetical protein	-
I2436_RS04615 (GDAKBCAL_00919)	-	982307..982633 (+)	327	WP_014622820.1	hypothetical protein	-
I2436_RS04620 (GDAKBCAL_00920)	-	982635..982910 (+)	276	WP_206153193.1	hypothetical protein	-
I2436_RS04625 (GDAKBCAL_00921)	-	982926..983327 (+)	402	WP_042670593.1	hypothetical protein	-
I2436_RS04630 (GDAKBCAL_00922)	-	983329..983574 (+)	246	WP_206153262.1	hypothetical protein	-
I2436_RS04635 (GDAKBCAL_00923)	-	983590..983997 (+)	408	WP_014622815.1	hypothetical protein	-
I2436_RS04640 (GDAKBCAL_00924)	-	984007..984297 (+)	291	WP_021320713.1	hypothetical protein	-
I2436_RS04645 (GDAKBCAL_00925)	-	984221..984604 (+)	384	WP_012678013.1	hypothetical protein	-
I2436_RS04650 (GDAKBCAL_00926)	-	984606..984857 (+)	252	WP_043029681.1	hypothetical protein	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25569.58 Da
• Isoelectric Point: 4.5644

>NTDB_id=506542 I2436_RS04600 WP_021320708.1 979386..980060(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide

• Length: 675 bp

>NTDB_id=506542 I2436_RS04600 WP_021320708.1 979386..980060(+) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (5-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-220)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus mutans UA159	84.615	98.661	0.835
ciaR	Streptococcus pneumoniae Rx1	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae D39	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae R6	80.543	98.661	0.795
ciaR	Streptococcus pneumoniae TIGR4	80.543	98.661	0.795
covR	Lactococcus lactis subsp. lactis strain DGCC12653	38.865	100	0.397