Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   I2436_RS03490 Genome accession   NZ_CP065060
Coordinates   733038..735191 (+) Length   717 a.a.
NCBI ID   WP_111690012.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ28     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 728038..740191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2436_RS03485 (GDAKBCAL_00693) - 731920..732579 (+) 660 WP_206153093.1 DNA-binding protein -
  I2436_RS03490 (GDAKBCAL_00694) comA 733038..735191 (+) 2154 WP_111690012.1 peptide cleavage/export ABC transporter Regulator
  I2436_RS03495 (GDAKBCAL_00695) - 735223..735384 (+) 162 WP_172454088.1 bacteriocin -
  I2436_RS03500 (GDAKBCAL_00696) - 735384..736697 (+) 1314 WP_111690014.1 GHKL domain-containing protein -
  I2436_RS03505 (GDAKBCAL_00697) - 736697..737446 (+) 750 WP_231146896.1 LytTR family DNA-binding domain-containing protein -
  I2436_RS03510 (GDAKBCAL_00698) - 737788..738315 (+) 528 WP_172454100.1 streptococcin A-M57 -
  I2436_RS03520 (GDAKBCAL_00700) - 739565..739795 (+) 231 WP_010817848.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 81306.31 Da        Isoelectric Point: 8.7986

>NTDB_id=506538 I2436_RS03490 WP_111690012.1 733038..735191(+) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MRFKKCHYRSQVDMKDCGVATLAMILEYYGSYYSLATLREMAKTTQDGTTALGLVKVAEALHFNTQAIQADMSLFDIENL
SFPFIAHVIKNETLLHYYTVIGCDKKNIHIADPDSSVGITKMSRKQFEKEWTGVTLFFIPSNCYKLYKEKKVSLWSFVPV
LKKQKLLISQIIGATLFITFINISGSYYLQAIIDNYIPNQMFHVLGIISIGLIIGYMIQQLVSYVQSQLLMILGQRLSIE
IILSYIKHVLHLPLSFFSTRRTGEIVSRFTDANAIIEALASTVLSVFLDVSVAIIVAVILCLQHPLLFLISILSLPIYTL
IVFLFMKPFERMNQEVMETNAKLSSSIIEDINGIETLKALSSEDTSYQKIDKEFTVHLKKSFTYYRSENIQKAIKTLLHL
LLNVFILWTGSKLVMSNQMTLGQLITFNTMLVYFTNPLENIVNLQTKLQKAHVANARLNEVYQIKSEFLSQQPMIDFKEW
KETITFTEVSFRYGYGAEVLSKIDFTIQKGSKVAFVGISGSGKTTLAKLLVNFYEPTHGEITLDHINLKKIDKKSLRHLI
TYLPQQPYIFNGTILENLLLGAPKDTTQKDIIEVLNFVELNTDIFRLPMQLQTELTSDGTELSGGQKQRIALARALLTKS
PILILDEATSSLDVLTEKKIINNLLALDKTILFIAHRLTIAERADRVIVLEKGQLIEDGTHETLLKKGGFYTHLMNG

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=506538 I2436_RS03490 WP_111690012.1 733038..735191(+) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGAGATTTAAGAAATGTCATTATCGGTCGCAAGTAGACATGAAAGATTGTGGTGTGGCTACTCTCGCAATGATACTTGA
ATATTATGGTTCGTATTATTCTTTGGCAACATTAAGAGAAATGGCAAAAACAACACAAGACGGAACTACTGCTCTAGGAC
TTGTTAAAGTAGCGGAAGCCTTACACTTTAATACACAAGCTATTCAAGCAGACATGTCACTATTTGACATAGAAAATCTA
TCATTTCCTTTTATTGCACATGTAATAAAGAATGAAACACTTTTACATTATTATACGGTAATAGGTTGTGATAAAAAGAA
TATTCATATTGCTGATCCAGATTCTTCTGTAGGAATAACGAAAATGTCTCGTAAACAGTTTGAGAAAGAATGGACAGGCG
TTACATTATTTTTTATACCGTCTAATTGTTATAAGCTATATAAGGAAAAGAAAGTTAGCTTATGGTCTTTTGTACCTGTT
TTGAAGAAACAAAAACTACTGATTAGTCAGATTATTGGGGCTACTTTATTTATAACTTTTATCAATATTAGTGGTTCTTA
TTACTTACAAGCTATTATTGATAATTATATCCCAAATCAAATGTTTCATGTATTAGGAATTATTTCTATAGGATTGATCA
TTGGTTATATGATACAACAATTAGTGTCATATGTTCAGTCACAATTGTTAATGATATTAGGACAACGTCTATCTATTGAG
ATTATTTTGTCTTATATCAAGCATGTTTTACATTTACCACTCTCTTTTTTCTCAACCCGAAGAACTGGAGAAATTGTTTC
TAGATTTACAGATGCAAATGCAATCATAGAGGCTTTAGCGAGTACAGTATTATCTGTCTTTTTAGATGTTTCTGTTGCTA
TAATCGTAGCAGTTATTTTATGTTTACAACATCCTCTATTATTTTTGATTAGTATTCTATCACTGCCGATTTATACTTTA
ATTGTCTTCCTATTCATGAAGCCATTTGAAAGAATGAATCAAGAGGTCATGGAAACTAATGCAAAATTATCGTCTTCTAT
TATTGAAGATATAAATGGAATAGAAACTCTTAAAGCATTATCAAGTGAAGATACAAGCTATCAAAAAATAGATAAAGAAT
TTACCGTACATTTAAAGAAATCATTCACTTACTATCGAAGTGAAAACATACAGAAAGCAATAAAAACTTTACTGCATTTA
TTATTGAATGTATTTATTTTATGGACAGGATCAAAACTTGTTATGAGTAATCAAATGACTTTAGGACAATTGATTACATT
CAATACCATGTTAGTATATTTTACAAATCCCTTAGAGAATATTGTGAATTTACAAACAAAACTACAAAAAGCACATGTGG
CAAATGCACGATTAAATGAAGTTTATCAAATTAAATCAGAGTTTTTATCTCAACAGCCGATGATTGATTTTAAAGAGTGG
AAAGAGACAATTACATTTACAGAGGTTAGTTTTCGATATGGATATGGTGCAGAGGTTTTAAGTAAAATTGATTTTACGAT
TCAAAAAGGAAGTAAAGTAGCTTTTGTTGGTATATCGGGGTCTGGTAAAACAACTTTGGCAAAGCTATTAGTAAATTTTT
ATGAACCTACTCATGGAGAAATAACATTAGATCATATAAACTTAAAGAAAATAGATAAGAAAAGCTTACGACATTTGATT
ACTTATCTTCCTCAACAGCCGTATATATTTAATGGAACAATTTTAGAAAATTTACTATTAGGTGCACCAAAAGATACAAC
GCAAAAGGATATTATAGAAGTATTAAATTTTGTTGAATTGAATACAGATATCTTTCGATTGCCTATGCAATTACAGACAG
AATTAACCTCTGACGGTACAGAATTATCTGGTGGACAAAAACAAAGAATTGCTTTAGCCAGAGCATTGCTTACAAAATCA
CCTATATTAATTTTAGATGAAGCAACAAGTAGTTTAGATGTATTAACCGAGAAAAAAATAATTAACAATCTATTAGCATT
AGATAAAACCATTTTATTCATTGCTCACCGTTTAACAATTGCGGAACGAGCAGATCGTGTCATTGTGTTAGAGAAAGGAC
AGCTCATTGAAGATGGTACACATGAAACACTGCTAAAAAAAGGCGGTTTCTATACCCATTTAATGAATGGTTAA

Domains

Predicted by InterProScan.

ABC transporter transmembrane region (ABC_membrane)

(172-438)

Peptidase C39 family (Peptidase_C39)

(7-141)

ABC transporter (ABC_tran)

(500-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis SK321

65.642

99.861

0.656
  comA Streptococcus pneumoniae D39

65.503

99.861

0.654
  comA Streptococcus pneumoniae R6

65.503

99.861

0.654
  comA Streptococcus mitis NCTC 12261

65.503

99.861

0.654
  comA Streptococcus pneumoniae Rx1

65.503

99.861

0.654
  comA Streptococcus pneumoniae TIGR4

65.363

99.861

0.653
  comA Streptococcus gordonii str. Challis substr. CH1

63.966

99.861

0.639
  comA/nlmT Streptococcus mutans UA159

54.951

100

0.55