Detailed information
Bioinformatically predicted
Overview
| Name | comA | Type | Regulator |
| Locus tag | I2436_RS03490 | Genome accession | NZ_CP065060 |
| Coordinates | 733038..735191 (+) | Length | 717 a.a. |
| NCBI ID | WP_111690012.1 | Uniprot ID | - |
| Organism | Streptococcus equi subsp. zooepidemicus strain SEZ28 | ||
| Function | processing and transport of ComC (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 710380..752049 | 733038..735191 | within | 0 |
Gene organization within MGE regions
Location: 710380..752049
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I2436_RS03420 (GDAKBCAL_00681) | - | 711134..711445 (+) | 312 | WP_111690001.1 | single-stranded DNA-binding protein | - |
| I2436_RS03425 (GDAKBCAL_00682) | - | 711449..711664 (+) | 216 | WP_000394022.1 | Maff2 family protein | - |
| I2436_RS03430 (GDAKBCAL_00683) | - | 711684..712550 (+) | 867 | WP_111690002.1 | CD0415/CD1112 family protein | - |
| I2436_RS03435 (GDAKBCAL_00684) | - | 712571..712834 (+) | 264 | WP_111690003.1 | conjugal transfer protein | - |
| I2436_RS03440 | - | 712838..713227 (+) | 390 | WP_111690004.1 | PrgI family protein | - |
| I2436_RS03445 (GDAKBCAL_00685) | - | 713139..715568 (+) | 2430 | WP_111690005.1 | ATP-binding protein | - |
| I2436_RS03450 (GDAKBCAL_00686) | - | 715572..717695 (+) | 2124 | WP_111690006.1 | CHAP domain-containing protein | - |
| I2436_RS03455 (GDAKBCAL_00687) | - | 717708..717947 (+) | 240 | WP_000711921.1 | hypothetical protein | - |
| I2436_RS03460 (GDAKBCAL_00688) | - | 717922..719475 (+) | 1554 | WP_111690007.1 | DUF4366 domain-containing protein | - |
| I2436_RS03465 (GDAKBCAL_00689) | - | 719570..721276 (+) | 1707 | WP_111690008.1 | DNA topoisomerase 3 | - |
| I2436_RS03470 (GDAKBCAL_00690) | - | 721360..721539 (+) | 180 | WP_111690009.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| I2436_RS03475 (GDAKBCAL_00691) | - | 721557..722984 (+) | 1428 | WP_206153237.1 | helix-turn-helix domain-containing protein | - |
| I2436_RS03480 (GDAKBCAL_00692) | - | 723158..731878 (+) | 8721 | WP_206153091.1 | helicase-related protein | - |
| I2436_RS03485 (GDAKBCAL_00693) | - | 731920..732579 (+) | 660 | WP_206153093.1 | DNA-binding protein | - |
| I2436_RS03490 (GDAKBCAL_00694) | comA | 733038..735191 (+) | 2154 | WP_111690012.1 | peptide cleavage/export ABC transporter | Regulator |
| I2436_RS03495 (GDAKBCAL_00695) | - | 735223..735384 (+) | 162 | WP_172454088.1 | bacteriocin | - |
| I2436_RS03500 (GDAKBCAL_00696) | - | 735384..736697 (+) | 1314 | WP_111690014.1 | GHKL domain-containing protein | - |
| I2436_RS03505 (GDAKBCAL_00697) | - | 736697..737446 (+) | 750 | WP_231146896.1 | LytTR family DNA-binding domain-containing protein | - |
| I2436_RS03510 (GDAKBCAL_00698) | - | 737788..738315 (+) | 528 | WP_172454100.1 | streptococcin A-M57 | - |
| I2436_RS03520 (GDAKBCAL_00700) | - | 739565..739795 (+) | 231 | WP_010817848.1 | Blp family class II bacteriocin | - |
| I2436_RS03525 (GDAKBCAL_00702) | - | 740270..740500 (+) | 231 | WP_111690016.1 | bacteriocin | - |
| I2436_RS03530 (GDAKBCAL_00704) | - | 741458..742465 (-) | 1008 | Protein_667 | relaxase/mobilization nuclease domain-containing protein | - |
| I2436_RS03535 (GDAKBCAL_00705) | - | 742583..744385 (-) | 1803 | WP_206152606.1 | reverse transcriptase domain-containing protein | - |
| I2436_RS03540 (GDAKBCAL_00706) | - | 744958..745284 (-) | 327 | Protein_669 | relaxase/mobilization nuclease domain-containing protein | - |
| I2436_RS03545 (GDAKBCAL_00707) | mobC | 745290..745640 (-) | 351 | WP_111690019.1 | plasmid mobilization relaxosome protein MobC | - |
| I2436_RS03550 (GDAKBCAL_00708) | - | 745944..746843 (+) | 900 | WP_111690020.1 | YafY family protein | - |
| I2436_RS03555 | - | 746908..747522 (+) | 615 | Protein_672 | GyrI-like domain-containing protein | - |
| I2436_RS03560 (GDAKBCAL_00711) | - | 747535..748086 (+) | 552 | WP_165622983.1 | ClbS/DfsB family four-helix bundle protein | - |
| I2436_RS03565 | - | 748091..748962 (+) | 872 | Protein_674 | radical SAM protein | - |
| I2436_RS03570 (GDAKBCAL_00713) | - | 749206..749616 (+) | 411 | WP_111690022.1 | sigma-70 family RNA polymerase sigma factor | - |
| I2436_RS03575 (GDAKBCAL_00714) | - | 750109..750279 (+) | 171 | WP_165622978.1 | hypothetical protein | - |
| I2436_RS03580 (GDAKBCAL_00715) | - | 750367..752049 (+) | 1683 | WP_111690024.1 | recombinase family protein | - |
Sequence
Protein
Download Length: 717 a.a. Molecular weight: 81306.31 Da Isoelectric Point: 8.7986
>NTDB_id=506538 I2436_RS03490 WP_111690012.1 733038..735191(+) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MRFKKCHYRSQVDMKDCGVATLAMILEYYGSYYSLATLREMAKTTQDGTTALGLVKVAEALHFNTQAIQADMSLFDIENL
SFPFIAHVIKNETLLHYYTVIGCDKKNIHIADPDSSVGITKMSRKQFEKEWTGVTLFFIPSNCYKLYKEKKVSLWSFVPV
LKKQKLLISQIIGATLFITFINISGSYYLQAIIDNYIPNQMFHVLGIISIGLIIGYMIQQLVSYVQSQLLMILGQRLSIE
IILSYIKHVLHLPLSFFSTRRTGEIVSRFTDANAIIEALASTVLSVFLDVSVAIIVAVILCLQHPLLFLISILSLPIYTL
IVFLFMKPFERMNQEVMETNAKLSSSIIEDINGIETLKALSSEDTSYQKIDKEFTVHLKKSFTYYRSENIQKAIKTLLHL
LLNVFILWTGSKLVMSNQMTLGQLITFNTMLVYFTNPLENIVNLQTKLQKAHVANARLNEVYQIKSEFLSQQPMIDFKEW
KETITFTEVSFRYGYGAEVLSKIDFTIQKGSKVAFVGISGSGKTTLAKLLVNFYEPTHGEITLDHINLKKIDKKSLRHLI
TYLPQQPYIFNGTILENLLLGAPKDTTQKDIIEVLNFVELNTDIFRLPMQLQTELTSDGTELSGGQKQRIALARALLTKS
PILILDEATSSLDVLTEKKIINNLLALDKTILFIAHRLTIAERADRVIVLEKGQLIEDGTHETLLKKGGFYTHLMNG
MRFKKCHYRSQVDMKDCGVATLAMILEYYGSYYSLATLREMAKTTQDGTTALGLVKVAEALHFNTQAIQADMSLFDIENL
SFPFIAHVIKNETLLHYYTVIGCDKKNIHIADPDSSVGITKMSRKQFEKEWTGVTLFFIPSNCYKLYKEKKVSLWSFVPV
LKKQKLLISQIIGATLFITFINISGSYYLQAIIDNYIPNQMFHVLGIISIGLIIGYMIQQLVSYVQSQLLMILGQRLSIE
IILSYIKHVLHLPLSFFSTRRTGEIVSRFTDANAIIEALASTVLSVFLDVSVAIIVAVILCLQHPLLFLISILSLPIYTL
IVFLFMKPFERMNQEVMETNAKLSSSIIEDINGIETLKALSSEDTSYQKIDKEFTVHLKKSFTYYRSENIQKAIKTLLHL
LLNVFILWTGSKLVMSNQMTLGQLITFNTMLVYFTNPLENIVNLQTKLQKAHVANARLNEVYQIKSEFLSQQPMIDFKEW
KETITFTEVSFRYGYGAEVLSKIDFTIQKGSKVAFVGISGSGKTTLAKLLVNFYEPTHGEITLDHINLKKIDKKSLRHLI
TYLPQQPYIFNGTILENLLLGAPKDTTQKDIIEVLNFVELNTDIFRLPMQLQTELTSDGTELSGGQKQRIALARALLTKS
PILILDEATSSLDVLTEKKIINNLLALDKTILFIAHRLTIAERADRVIVLEKGQLIEDGTHETLLKKGGFYTHLMNG
Nucleotide
Download Length: 2154 bp
>NTDB_id=506538 I2436_RS03490 WP_111690012.1 733038..735191(+) (comA) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGAGATTTAAGAAATGTCATTATCGGTCGCAAGTAGACATGAAAGATTGTGGTGTGGCTACTCTCGCAATGATACTTGA
ATATTATGGTTCGTATTATTCTTTGGCAACATTAAGAGAAATGGCAAAAACAACACAAGACGGAACTACTGCTCTAGGAC
TTGTTAAAGTAGCGGAAGCCTTACACTTTAATACACAAGCTATTCAAGCAGACATGTCACTATTTGACATAGAAAATCTA
TCATTTCCTTTTATTGCACATGTAATAAAGAATGAAACACTTTTACATTATTATACGGTAATAGGTTGTGATAAAAAGAA
TATTCATATTGCTGATCCAGATTCTTCTGTAGGAATAACGAAAATGTCTCGTAAACAGTTTGAGAAAGAATGGACAGGCG
TTACATTATTTTTTATACCGTCTAATTGTTATAAGCTATATAAGGAAAAGAAAGTTAGCTTATGGTCTTTTGTACCTGTT
TTGAAGAAACAAAAACTACTGATTAGTCAGATTATTGGGGCTACTTTATTTATAACTTTTATCAATATTAGTGGTTCTTA
TTACTTACAAGCTATTATTGATAATTATATCCCAAATCAAATGTTTCATGTATTAGGAATTATTTCTATAGGATTGATCA
TTGGTTATATGATACAACAATTAGTGTCATATGTTCAGTCACAATTGTTAATGATATTAGGACAACGTCTATCTATTGAG
ATTATTTTGTCTTATATCAAGCATGTTTTACATTTACCACTCTCTTTTTTCTCAACCCGAAGAACTGGAGAAATTGTTTC
TAGATTTACAGATGCAAATGCAATCATAGAGGCTTTAGCGAGTACAGTATTATCTGTCTTTTTAGATGTTTCTGTTGCTA
TAATCGTAGCAGTTATTTTATGTTTACAACATCCTCTATTATTTTTGATTAGTATTCTATCACTGCCGATTTATACTTTA
ATTGTCTTCCTATTCATGAAGCCATTTGAAAGAATGAATCAAGAGGTCATGGAAACTAATGCAAAATTATCGTCTTCTAT
TATTGAAGATATAAATGGAATAGAAACTCTTAAAGCATTATCAAGTGAAGATACAAGCTATCAAAAAATAGATAAAGAAT
TTACCGTACATTTAAAGAAATCATTCACTTACTATCGAAGTGAAAACATACAGAAAGCAATAAAAACTTTACTGCATTTA
TTATTGAATGTATTTATTTTATGGACAGGATCAAAACTTGTTATGAGTAATCAAATGACTTTAGGACAATTGATTACATT
CAATACCATGTTAGTATATTTTACAAATCCCTTAGAGAATATTGTGAATTTACAAACAAAACTACAAAAAGCACATGTGG
CAAATGCACGATTAAATGAAGTTTATCAAATTAAATCAGAGTTTTTATCTCAACAGCCGATGATTGATTTTAAAGAGTGG
AAAGAGACAATTACATTTACAGAGGTTAGTTTTCGATATGGATATGGTGCAGAGGTTTTAAGTAAAATTGATTTTACGAT
TCAAAAAGGAAGTAAAGTAGCTTTTGTTGGTATATCGGGGTCTGGTAAAACAACTTTGGCAAAGCTATTAGTAAATTTTT
ATGAACCTACTCATGGAGAAATAACATTAGATCATATAAACTTAAAGAAAATAGATAAGAAAAGCTTACGACATTTGATT
ACTTATCTTCCTCAACAGCCGTATATATTTAATGGAACAATTTTAGAAAATTTACTATTAGGTGCACCAAAAGATACAAC
GCAAAAGGATATTATAGAAGTATTAAATTTTGTTGAATTGAATACAGATATCTTTCGATTGCCTATGCAATTACAGACAG
AATTAACCTCTGACGGTACAGAATTATCTGGTGGACAAAAACAAAGAATTGCTTTAGCCAGAGCATTGCTTACAAAATCA
CCTATATTAATTTTAGATGAAGCAACAAGTAGTTTAGATGTATTAACCGAGAAAAAAATAATTAACAATCTATTAGCATT
AGATAAAACCATTTTATTCATTGCTCACCGTTTAACAATTGCGGAACGAGCAGATCGTGTCATTGTGTTAGAGAAAGGAC
AGCTCATTGAAGATGGTACACATGAAACACTGCTAAAAAAAGGCGGTTTCTATACCCATTTAATGAATGGTTAA
ATGAGATTTAAGAAATGTCATTATCGGTCGCAAGTAGACATGAAAGATTGTGGTGTGGCTACTCTCGCAATGATACTTGA
ATATTATGGTTCGTATTATTCTTTGGCAACATTAAGAGAAATGGCAAAAACAACACAAGACGGAACTACTGCTCTAGGAC
TTGTTAAAGTAGCGGAAGCCTTACACTTTAATACACAAGCTATTCAAGCAGACATGTCACTATTTGACATAGAAAATCTA
TCATTTCCTTTTATTGCACATGTAATAAAGAATGAAACACTTTTACATTATTATACGGTAATAGGTTGTGATAAAAAGAA
TATTCATATTGCTGATCCAGATTCTTCTGTAGGAATAACGAAAATGTCTCGTAAACAGTTTGAGAAAGAATGGACAGGCG
TTACATTATTTTTTATACCGTCTAATTGTTATAAGCTATATAAGGAAAAGAAAGTTAGCTTATGGTCTTTTGTACCTGTT
TTGAAGAAACAAAAACTACTGATTAGTCAGATTATTGGGGCTACTTTATTTATAACTTTTATCAATATTAGTGGTTCTTA
TTACTTACAAGCTATTATTGATAATTATATCCCAAATCAAATGTTTCATGTATTAGGAATTATTTCTATAGGATTGATCA
TTGGTTATATGATACAACAATTAGTGTCATATGTTCAGTCACAATTGTTAATGATATTAGGACAACGTCTATCTATTGAG
ATTATTTTGTCTTATATCAAGCATGTTTTACATTTACCACTCTCTTTTTTCTCAACCCGAAGAACTGGAGAAATTGTTTC
TAGATTTACAGATGCAAATGCAATCATAGAGGCTTTAGCGAGTACAGTATTATCTGTCTTTTTAGATGTTTCTGTTGCTA
TAATCGTAGCAGTTATTTTATGTTTACAACATCCTCTATTATTTTTGATTAGTATTCTATCACTGCCGATTTATACTTTA
ATTGTCTTCCTATTCATGAAGCCATTTGAAAGAATGAATCAAGAGGTCATGGAAACTAATGCAAAATTATCGTCTTCTAT
TATTGAAGATATAAATGGAATAGAAACTCTTAAAGCATTATCAAGTGAAGATACAAGCTATCAAAAAATAGATAAAGAAT
TTACCGTACATTTAAAGAAATCATTCACTTACTATCGAAGTGAAAACATACAGAAAGCAATAAAAACTTTACTGCATTTA
TTATTGAATGTATTTATTTTATGGACAGGATCAAAACTTGTTATGAGTAATCAAATGACTTTAGGACAATTGATTACATT
CAATACCATGTTAGTATATTTTACAAATCCCTTAGAGAATATTGTGAATTTACAAACAAAACTACAAAAAGCACATGTGG
CAAATGCACGATTAAATGAAGTTTATCAAATTAAATCAGAGTTTTTATCTCAACAGCCGATGATTGATTTTAAAGAGTGG
AAAGAGACAATTACATTTACAGAGGTTAGTTTTCGATATGGATATGGTGCAGAGGTTTTAAGTAAAATTGATTTTACGAT
TCAAAAAGGAAGTAAAGTAGCTTTTGTTGGTATATCGGGGTCTGGTAAAACAACTTTGGCAAAGCTATTAGTAAATTTTT
ATGAACCTACTCATGGAGAAATAACATTAGATCATATAAACTTAAAGAAAATAGATAAGAAAAGCTTACGACATTTGATT
ACTTATCTTCCTCAACAGCCGTATATATTTAATGGAACAATTTTAGAAAATTTACTATTAGGTGCACCAAAAGATACAAC
GCAAAAGGATATTATAGAAGTATTAAATTTTGTTGAATTGAATACAGATATCTTTCGATTGCCTATGCAATTACAGACAG
AATTAACCTCTGACGGTACAGAATTATCTGGTGGACAAAAACAAAGAATTGCTTTAGCCAGAGCATTGCTTACAAAATCA
CCTATATTAATTTTAGATGAAGCAACAAGTAGTTTAGATGTATTAACCGAGAAAAAAATAATTAACAATCTATTAGCATT
AGATAAAACCATTTTATTCATTGCTCACCGTTTAACAATTGCGGAACGAGCAGATCGTGTCATTGTGTTAGAGAAAGGAC
AGCTCATTGAAGATGGTACACATGAAACACTGCTAAAAAAAGGCGGTTTCTATACCCATTTAATGAATGGTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comA | Streptococcus mitis SK321 |
65.642 |
99.861 |
0.656 |
| comA | Streptococcus pneumoniae D39 |
65.503 |
99.861 |
0.654 |
| comA | Streptococcus pneumoniae R6 |
65.503 |
99.861 |
0.654 |
| comA | Streptococcus mitis NCTC 12261 |
65.503 |
99.861 |
0.654 |
| comA | Streptococcus pneumoniae Rx1 |
65.503 |
99.861 |
0.654 |
| comA | Streptococcus pneumoniae TIGR4 |
65.363 |
99.861 |
0.653 |
| comA | Streptococcus gordonii str. Challis substr. CH1 |
63.966 |
99.861 |
0.639 |
| comA/nlmT | Streptococcus mutans UA159 |
54.951 |
100 |
0.55 |