Detailed information NTG0506455

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: I2434_RS09850
• Genome accession: NZ_CP065058
• Coordinates: 2080002..2081225 (+)
• Length: 407 a.a.
• NCBI ID: WP_012516520.1
• Uniprot ID: A0AAW3GJZ4
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ18
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2075002..2086225

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2434_RS09830 (MCPGFBBE_01971)	-	2076138..2076410 (+)	273	WP_012678721.1	Veg family protein	-
I2434_RS09835 (MCPGFBBE_01972)	rpsD	2076935..2077546 (+)	612	WP_012516485.1	30S ribosomal protein S4	-
I2434_RS09840 (MCPGFBBE_01973)	-	2077675..2078934 (-)	1260	WP_111677636.1	ISL3-like element ISSeq1 family transposase	-
I2434_RS09845 (MCPGFBBE_01974)	rlmH	2079313..2079792 (-)	480	WP_012678751.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
I2434_RS09850 (MCPGFBBE_01975)	htrA	2080002..2081225 (+)	1224	WP_012516520.1	trypsin-like peptidase domain-containing protein	Regulator
I2434_RS09855 (MCPGFBBE_01976)	spo0J	2081345..2082118 (+)	774	WP_015898719.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 407 a.a.
• Molecular weight: 42434.01 Da
• Isoelectric Point: 5.4809

>NTDB_id=506455 I2434_RS09850 WP_012516520.1 2080002..2081225(+) (htrA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MLKSKNILKPLWVLAIGFLGGLLAALVVNGFSQNSLTSSNAKGATTTSNVSFNNTTDTTKAVKVVQDAVVSVINYQKAAS
PAISNPYINLFGEENDTSAVQKEDELSIHSEGSGVVYKKEGNTAYLVTNNHVIEGAQRIEILTADGSKIVGELVGADTYS
DLAVVKVAADKIKTIAKFADSTKINVGEVAIAIGSPLGTKYANSVTEGIVSSLSRTVTSRNEAGETISTNAIQTDAAINP
GNSGGPLINIEGQVIGINSSKISSTPTGSGGAIEGIGFAIPSSDVVTIINQLESNGAVIRPALGITMVNLSNLSTNALIQ
LNIPTSVTSGVVVASTQDGMPALGKLEQYDVITEVDGKEVSSISDLQSVLYSHEINDTIKVTFYRGTAKKKVDIKLTKTT
KDLTKKQ

Nucleotide

• Length: 1224 bp

>NTDB_id=506455 I2434_RS09850 WP_012516520.1 2080002..2081225(+) (htrA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
GTGTTAAAATCAAAAAATATATTGAAGCCCTTATGGGTTTTAGCCATTGGATTTTTAGGGGGCTTATTAGCTGCCTTAGT
TGTTAATGGATTTAGTCAGAATTCTCTAACATCTTCAAATGCAAAGGGAGCAACGACAACAAGCAACGTCAGCTTTAACA
ATACAACTGATACAACAAAGGCTGTTAAGGTGGTTCAAGATGCTGTAGTGTCTGTTATTAACTATCAAAAGGCTGCTTCG
CCTGCCATTTCAAATCCTTACATCAATCTTTTCGGAGAAGAAAATGATACCTCAGCAGTACAAAAAGAGGACGAGCTAAG
CATACACAGTGAAGGTTCGGGTGTTGTCTACAAAAAAGAAGGAAATACTGCTTATCTTGTAACCAACAATCATGTTATTG
AGGGAGCTCAACGAATTGAAATTTTAACAGCAGACGGCTCTAAGATCGTTGGAGAACTAGTTGGTGCAGACACTTATTCT
GACCTAGCTGTTGTCAAAGTTGCTGCTGATAAAATCAAAACAATAGCCAAATTTGCAGATTCAACCAAAATTAATGTTGG
AGAGGTAGCCATTGCAATTGGTAGTCCTCTTGGAACAAAATATGCCAACTCAGTGACAGAAGGGATTGTTTCAAGTCTAA
GCCGTACAGTCACTTCAAGAAATGAGGCAGGCGAGACCATCTCAACAAATGCTATCCAAACTGATGCTGCTATCAATCCA
GGTAATTCAGGTGGACCACTCATCAATATTGAAGGCCAGGTTATTGGTATCAACTCAAGTAAAATATCCTCAACACCTAC
TGGTAGCGGCGGAGCCATTGAGGGAATTGGCTTTGCTATTCCATCAAGCGATGTTGTCACCATTATTAACCAACTAGAGT
CTAACGGAGCTGTTATCAGACCAGCCTTAGGCATTACAATGGTAAACTTAAGTAATCTATCAACCAATGCATTGATTCAA
TTGAATATTCCAACAAGCGTTACCAGCGGTGTTGTCGTAGCCTCTACCCAGGATGGCATGCCTGCTCTTGGTAAATTGGA
GCAGTATGATGTCATTACTGAGGTTGACGGTAAAGAAGTCAGCTCAATTAGTGACCTACAAAGTGTCTTATATAGTCATG
AGATTAACGACACCATTAAGGTAACCTTCTACAGAGGAACTGCTAAGAAGAAAGTTGACATCAAATTAACAAAAACAACT
AAGGATCTAACTAAAAAGCAGTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (112-257)

• PDZ domain (PDZ_2) (301-396)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.275	100	0.614
htrA	Streptococcus gordonii str. Challis substr. CH1	57.855	98.526	0.57
htrA	Streptococcus mitis NCTC 12261	54.66	97.543	0.533
htrA	Streptococcus pneumoniae Rx1	53.634	98.034	0.526
htrA	Streptococcus pneumoniae D39	53.634	98.034	0.526
htrA	Streptococcus pneumoniae R6	53.634	98.034	0.526
htrA	Streptococcus pneumoniae TIGR4	53.634	98.034	0.526