Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   I2434_RS08555 Genome accession   NZ_CP065058
Coordinates   1807566..1808330 (-) Length   254 a.a.
NCBI ID   WP_012677379.1    Uniprot ID   A0AAW3GKI0
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1802566..1813330
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS08535 (MCPGFBBE_01716) - 1802904..1804130 (-) 1227 WP_165623520.1 cysteine desulfurase -
  I2434_RS08540 (MCPGFBBE_01717) sufD 1804157..1805419 (-) 1263 WP_165623519.1 Fe-S cluster assembly protein SufD -
  I2434_RS08545 (MCPGFBBE_01718) sufC 1805511..1806281 (-) 771 WP_012516290.1 Fe-S cluster assembly ATPase SufC -
  I2434_RS08550 (MCPGFBBE_01719) - 1806402..1807559 (-) 1158 WP_012680099.1 MraY family glycosyltransferase -
  I2434_RS08555 (MCPGFBBE_01720) mecA 1807566..1808330 (-) 765 WP_012677379.1 adaptor protein MecA Regulator
  I2434_RS08560 (MCPGFBBE_01721) - 1808450..1809289 (-) 840 WP_138119780.1 undecaprenyl-diphosphate phosphatase -
  I2434_RS08565 (MCPGFBBE_01722) - 1809605..1811173 (+) 1569 WP_043039427.1 ABC transporter substrate-binding protein/permease -
  I2434_RS08570 (MCPGFBBE_01723) - 1811166..1811906 (+) 741 WP_012680102.1 amino acid ABC transporter ATP-binding protein -
  I2434_RS08575 (MCPGFBBE_01724) - 1812229..1812345 (+) 117 WP_012677375.1 putative metal homeostasis protein -

Sequence

Protein


Download         Length: 254 a.a.        Molecular weight: 29250.07 Da        Isoelectric Point: 4.2228

>NTDB_id=506449 I2434_RS08555 WP_012677379.1 1807566..1808330(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYAVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSDL
NKDLNFEDLADLGDISQMTPEDFFRSLEQSMREKGDVNAHEKLEKIEEIMEDVVDATLAEQADSKEAAELDEPTEPLDYV
HYVLDFASVRDAVCFAKVIDFPIEASELYKGPRHYHMTILLDVQNKPAYFANVMYARLIEHASPGTKTRAYLQEHGCQLI
FDGAVEELQKIRLG

Nucleotide


Download         Length: 765 bp        

>NTDB_id=506449 I2434_RS08555 WP_012677379.1 1807566..1808330(-) (mecA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGGGGTATGGAACT
CAAGGACTTCTTGATCCCTCAAGAAAAGACAGAGGAGTTCTTTTATGCTGTTATGGACGAGTTGGACCTTCCGGACAATT
TTAAGGACAGTGGTATGCTTAGCTTTCGAGTGACTCCAAGAAAGGATCGCTTAGATGTTTTTGTGACCAAATCAGACCTC
AATAAGGACCTTAATTTTGAGGATTTGGCAGACCTAGGTGATATTTCTCAAATGACTCCAGAGGATTTTTTCAGGAGCTT
GGAGCAGTCTATGCGTGAAAAGGGTGATGTCAATGCCCATGAAAAGCTTGAAAAAATCGAGGAGATCATGGAGGACGTGG
TTGATGCTACCTTGGCTGAGCAAGCAGATAGTAAGGAAGCTGCTGAGCTTGATGAGCCGACAGAGCCACTTGATTATGTT
CACTATGTTCTTGATTTTGCTTCTGTTCGAGACGCTGTTTGCTTTGCTAAGGTGATTGATTTTCCGATCGAGGCTTCTGA
ATTGTATAAGGGTCCTCGTCATTATCACATGACGATTTTACTTGATGTGCAAAATAAGCCTGCCTACTTTGCCAATGTGA
TGTATGCCAGATTGATTGAGCATGCTAGTCCTGGTACAAAAACAAGAGCTTATTTGCAGGAGCATGGTTGTCAGCTCATT
TTTGATGGTGCTGTTGAGGAGCTACAAAAAATCAGGTTGGGGTAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.745

98.819

0.63
  mecA Streptococcus thermophilus LMD-9

57.255

100

0.575
  mecA Streptococcus thermophilus LMG 18311

56.471

100

0.567
  mecA Streptococcus pneumoniae TIGR4

48.031

100

0.48
  mecA Streptococcus pneumoniae Rx1

47.638

100

0.476
  mecA Streptococcus pneumoniae D39

47.638

100

0.476
  mecA Streptococcus pneumoniae R6

47.638

100

0.476