Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   I2434_RS07630 Genome accession   NZ_CP065058
Coordinates   1625823..1627979 (+) Length   718 a.a.
NCBI ID   WP_165623393.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 1620823..1632979
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS07585 (MCPGFBBE_01526) - 1621093..1621674 (-) 582 WP_043053340.1 GNAT family N-acetyltransferase -
  I2434_RS07590 (MCPGFBBE_01527) - 1621918..1622343 (-) 426 WP_228294449.1 bacteriocin immunity protein -
  I2434_RS07595 (MCPGFBBE_01528) - 1622363..1622599 (-) 237 WP_165623394.1 bacteriocin class II family protein -
  I2434_RS07600 (MCPGFBBE_01529) - 1623131..1623334 (-) 204 WP_012679939.1 bacteriocin -
  I2434_RS07605 (MCPGFBBE_01530) - 1623351..1623605 (-) 255 WP_043053342.1 Blp family class II bacteriocin -
  I2434_RS07610 (MCPGFBBE_01531) - 1624342..1624641 (-) 300 WP_014623336.1 bacteriocin immunity protein -
  I2434_RS07615 (MCPGFBBE_01532) - 1624648..1624896 (-) 249 WP_014623337.1 garvicin Q family class II bacteriocin -
  I2434_RS07620 (MCPGFBBE_01533) - 1625050..1625346 (-) 297 WP_012516111.1 bacteriocin immunity protein -
  I2434_RS07625 (MCPGFBBE_01534) - 1625346..1625564 (-) 219 WP_021321057.1 leucocin A/sakacin P family class II bacteriocin -
  I2434_RS07630 (MCPGFBBE_01535) comA/nlmT 1625823..1627979 (+) 2157 WP_165623393.1 peptide cleavage/export ABC transporter Regulator
  I2434_RS07635 (MCPGFBBE_01536) - 1627990..1629347 (+) 1358 Protein_1488 bacteriocin secretion accessory protein -
  I2434_RS07640 (MCPGFBBE_01537) - 1629447..1629581 (+) 135 WP_043030066.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I2434_RS07645 (MCPGFBBE_01538) - 1629700..1631034 (-) 1335 WP_165623392.1 GHKL domain-containing protein -
  I2434_RS07650 (MCPGFBBE_01539) comE/blpR 1631034..1631783 (-) 750 WP_042671079.1 response regulator transcription factor Regulator
  I2434_RS07655 (MCPGFBBE_01540) - 1632410..1632613 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  I2434_RS07660 (MCPGFBBE_01541) - 1632630..1632887 (-) 258 WP_038674051.1 Blp family class II bacteriocin -

Sequence

Protein


Download         Length: 718 a.a.        Molecular weight: 80589.75 Da        Isoelectric Point: 7.4612

>NTDB_id=506435 I2434_RS07630 WP_165623393.1 1625823..1627979(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MTLFYKRTFVPQIDARDCGVAALASIARYYGSDYSLAYLRELAKTNKEGTTALGIVMAAKEMGFETRPIQADMTLFDMAD
VPYPLIVHVNKEGKLQHYYVVYKSKKDYLIIGDPDPMVKVTKMSKERFASEWTGVTICLAPKPNYKPHKDQKNGLLGFFP
LIFKQRALIFYIVLASVLVTVINISGSYYLQGILDEYIPNQLKSTLGIVSIGLIITYILQQLMSFSRDYLLTVLSQRLTI
DVILSYIRHIFELPMSFFATRRTGEVTSRFTDANSIIDALASTILSLFLDLSILAIVGSVLLVQNSRLFLLSLISIPVYT
IIICAFIKPFEQMNHDVMQSNAMLSSAIIEDINGIETIKSLTSEENRYQKIDSDFVDYLDKSFKLSKYTILQATLKQGAQ
LILNIIILWFGAQLVINGKISIGQLITFNTLLAYFTTPLENIINLQTKLQAAKVANNRLNEVYLVESEFKASQALYDLSL
LQGDIQFEAVSYRYGFGKDTLSDITLTIKQGAKVTLVGVSGSGKTTLAKMLVNFFEPYKGRITINQNDLKTIDKKNLRQY
INYLPQQAYIFNGSILENLTLGAKQGISQEDILNACEIADIRHDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTQA
PILVLDEATSGLDILTEKKIIDRLMNMTDKTIIFVAHRLSIAERTDQVVVLNQGQIIETGSHQELMKQGGFYYHLFSE

Nucleotide


Download         Length: 2157 bp        

>NTDB_id=506435 I2434_RS07630 WP_165623393.1 1625823..1627979(+) (comA/nlmT) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGACACTTTTTTATAAAAGAACCTTTGTACCACAAATAGATGCCAGAGATTGTGGCGTAGCTGCTCTAGCCTCAATCGC
AAGGTATTATGGTTCAGATTATTCATTAGCTTATTTGAGAGAATTAGCAAAGACCAATAAGGAAGGGACAACAGCCCTCG
GTATTGTCATGGCTGCTAAGGAAATGGGGTTTGAAACCAGACCTATTCAAGCGGATATGACCCTCTTTGACATGGCAGAC
GTGCCCTATCCATTGATCGTCCATGTCAATAAAGAAGGAAAGCTACAGCACTACTATGTGGTCTACAAATCTAAAAAAGA
CTATCTTATCATTGGTGATCCCGATCCAATGGTCAAGGTCACAAAAATGTCCAAGGAACGCTTTGCTTCTGAATGGACAG
GTGTCACCATATGCCTTGCTCCTAAGCCAAATTATAAACCACATAAAGACCAAAAAAATGGACTATTAGGCTTCTTTCCG
CTTATTTTTAAACAGCGAGCCCTTATATTTTATATCGTGTTAGCTTCTGTCTTGGTAACGGTCATTAATATTTCTGGTTC
ATACTATCTCCAAGGGATTTTAGACGAGTATATTCCAAATCAGCTGAAATCTACCTTAGGGATTGTATCAATTGGTCTCA
TCATTACCTATATACTCCAGCAGCTAATGAGCTTTTCTAGAGATTATCTTTTAACTGTCCTTAGCCAACGTCTTACGATT
GATGTGATCCTGTCCTATATCCGCCATATTTTCGAATTGCCGATGTCCTTTTTTGCAACACGTCGAACAGGTGAGGTAAC
CTCGCGCTTTACAGATGCTAACTCTATCATTGACGCACTCGCTTCAACCATTTTATCCCTCTTTCTAGACCTCTCTATAT
TAGCTATTGTCGGAAGTGTTCTTTTGGTGCAAAATAGCAGGCTTTTTCTGCTATCTCTGATTTCTATCCCAGTATATACC
ATTATCATATGTGCCTTTATAAAGCCGTTTGAACAAATGAATCATGATGTGATGCAAAGCAATGCCATGCTAAGCTCTGC
TATTATCGAAGATATCAACGGGATCGAAACCATAAAATCACTAACCAGTGAAGAAAACCGTTACCAAAAAATTGACAGCG
ACTTTGTGGATTACCTTGATAAGTCTTTTAAGCTTAGTAAATATACCATCTTACAAGCCACACTTAAGCAAGGAGCGCAG
CTAATTCTGAATATCATCATTCTTTGGTTTGGGGCTCAACTGGTCATTAATGGTAAAATTTCAATCGGGCAATTAATTAC
CTTTAACACACTTCTTGCCTATTTTACAACCCCTTTAGAAAATATCATTAATCTTCAAACCAAGCTCCAAGCAGCTAAGG
TTGCCAATAATCGTCTCAATGAGGTCTATCTTGTAGAGTCCGAATTTAAAGCCTCGCAAGCCTTATACGATTTATCGCTC
TTACAGGGTGACATTCAGTTTGAAGCTGTTTCCTACAGGTATGGCTTTGGCAAGGATACATTATCAGATATTACATTAAC
CATTAAGCAGGGAGCAAAAGTAACCCTTGTTGGTGTCAGCGGCTCAGGAAAAACAACCCTAGCCAAGATGCTCGTCAATT
TCTTTGAACCTTATAAGGGACGTATAACCATCAACCAAAACGATCTCAAGACCATTGATAAAAAGAATCTTCGACAATAC
ATCAACTACCTTCCACAACAAGCCTATATCTTTAATGGATCTATCTTAGAAAATCTAACCTTGGGAGCCAAGCAAGGCAT
CAGCCAGGAAGACATTCTTAACGCCTGTGAGATTGCTGACATTCGTCACGACATCGAGCAAATGCCAATGGGATACCAAA
CCGAGCTCTCTGATGGGGCTGGCTTATCTGGCGGACAAAAACAGAGAATTGCACTTGCTAGAGCATTACTAACCCAAGCT
CCTATACTAGTTCTTGATGAAGCAACCAGCGGACTTGACATACTGACAGAAAAGAAAATCATTGACCGTCTCATGAACAT
GACAGACAAAACGATTATTTTCGTTGCCCACCGGCTTAGTATCGCAGAGCGCACTGATCAGGTTGTTGTTCTTAATCAAG
GGCAAATCATTGAGACAGGCAGCCACCAGGAATTAATGAAACAAGGTGGATTTTATTACCACCTATTTAGTGAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(169-439)

Peptidase C39 family (Peptidase_C39)

(8-143)

ABC transporter (ABC_tran)

(501-650)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

71.269

99.861

0.712
  comA Streptococcus mitis SK321

67.602

99.304

0.671
  comA Streptococcus mitis NCTC 12261

67.321

99.304

0.669
  comA Streptococcus pneumoniae Rx1

66.9

99.304

0.664
  comA Streptococcus pneumoniae D39

66.9

99.304

0.664
  comA Streptococcus pneumoniae R6

66.9

99.304

0.664
  comA Streptococcus pneumoniae TIGR4

66.62

99.304

0.662
  comA Streptococcus gordonii str. Challis substr. CH1

65.358

99.304

0.649