Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   I2434_RS06790 Genome accession   NZ_CP065058
Coordinates   1444220..1444930 (-) Length   236 a.a.
NCBI ID   WP_206157575.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ18     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1439220..1449930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2434_RS06775 (MCPGFBBE_01356) - 1440129..1441871 (-) 1743 WP_206157574.1 restriction endonuclease FokI C-terminal domain-containing protein -
  I2434_RS06780 (MCPGFBBE_01357) vicX 1442062..1442871 (-) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2434_RS06785 (MCPGFBBE_01358) vicK 1442875..1444227 (-) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2434_RS06790 (MCPGFBBE_01359) vicR 1444220..1444930 (-) 711 WP_206157575.1 response regulator YycF Regulator
  I2434_RS06795 (MCPGFBBE_01360) - 1445131..1446147 (-) 1017 WP_206157576.1 DUF3114 domain-containing protein -
  I2434_RS06800 (MCPGFBBE_01361) - 1446193..1447455 (-) 1263 WP_206157577.1 AMP-binding protein -
  I2434_RS06805 (MCPGFBBE_01362) - 1447445..1448560 (-) 1116 WP_206156669.1 acetyl-CoA C-acyltransferase -
  I2434_RS06810 (MCPGFBBE_01363) - 1448557..1449096 (-) 540 WP_111710696.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27009.85 Da        Isoelectric Point: 4.9038

>NTDB_id=506432 I2434_RS06790 WP_206157575.1 1444220..1444930(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MKKILIVDDEKPISDIIKFNLTKEGYDTVTAFDGKEAVAVFEEERPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFIAKKHGQEVE
LTHREFELLHHLANHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKAYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=506432 I2434_RS06790 WP_206157575.1 1444220..1444930(-) (vicR) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGAAGAAAATACTGATTGTTGATGATGAAAAGCCGATTTCTGATATCATTAAATTTAATCTGACAAAGGAAGGCTATGA
TACGGTCACAGCATTTGATGGCAAAGAGGCCGTTGCAGTCTTTGAAGAGGAAAGGCCGGATTTGATTATTTTGGATTTGA
TGCTTCCTGAGCTAGATGGTCTTGAGGTAGCCAAGGAAATCCGCAAGACCAGCCATATTCCTATCATCATGCTATCTGCT
AAGGATAGCGAATTTGATAAGGTGATTGGACTTGAAATAGGGGCTGATGATTATGTGACTAAGCCCTTTTCAAATCGTGA
GCTGCTGGCGCGTGTCAAGGCACATTTGCGTCGGACAGAGACTATTGAGACAGCAGTAGCCGAAGAAAATGCCTCCTCAG
GCTCTCAGGAGCTAACCATCGGCAATCTACAGATTTTACCAGATGCCTTTATCGCTAAAAAGCATGGTCAAGAGGTTGAG
CTGACCCATCGTGAGTTTGAATTGCTGCATCATCTGGCAAACCATATCGGACAGGTCATGACACGTGAGCATTTGCTTGA
GACCGTATGGGGCTACGATTATTTTGGCGATGTCCGAACCGTTGACGTTACTATCCGTCGCCTGCGCGAAAAAATAGAGG
ATACACCGAGTCGTCCAGAGTATATTTTGACAAGACGTGGTGTTGGGTACTACATGAAGGCTTATGACTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

88.983

100

0.89
  micA Streptococcus pneumoniae Cp1015

78.112

98.729

0.771
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.034

99.153

0.377