Detailed information NTG0506425

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: I2434_RS04830
• Genome accession: NZ_CP065058
• Coordinates: 1025864..1026709 (+)
• Length: 281 a.a.
• NCBI ID: WP_012677974.1
• Uniprot ID: A0A6M1KS91
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ18
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1020864..1031709

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2434_RS04815 (MCPGFBBE_00956)	-	1022766..1023398 (+)	633	WP_165623381.1	ABC transporter ATP-binding protein	-
I2434_RS04820 (MCPGFBBE_00957)	ylqF	1023991..1024845 (+)	855	WP_012677976.1	ribosome biogenesis GTPase YlqF	-
I2434_RS04825 (MCPGFBBE_00958)	-	1024826..1025608 (+)	783	WP_165623389.1	ribonuclease HII	-
I2434_RS04830 (MCPGFBBE_00959)	dprA	1025864..1026709 (+)	846	WP_012677974.1	DNA-processing protein DprA	Machinery gene
I2434_RS04835 (MCPGFBBE_00960)	topA	1026816..1028948 (+)	2133	WP_165623382.1	type I DNA topoisomerase	-
I2434_RS04840 (MCPGFBBE_00961)	-	1029063..1029710 (+)	648	WP_043030796.1	SatD family protein	-
I2434_RS04845 (MCPGFBBE_00962)	-	1029731..1030444 (+)	714	WP_111690112.1	DUF3307 domain-containing protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 31330.23 Da
• Isoelectric Point: 8.8540

>NTDB_id=506425 I2434_RS04830 WP_012677974.1 1025864..1026709(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
MNNFELYKLKKAGLTNLNILNLIDYQQRNNKSLSLRDIAVVSCCKNPVLFIETYKQLNVALLKKEFNQFPSLSILDKQYP
LALREIYNPPVLLFYQGDLSLLEKPKLAVVGSRESSEIGTRSVYKIIKELKNHFVIVSGLARGIDTSAHLACLKAGGQTI
AVIGTGLDRYYPKENHQLQEFLSQRHLVLSEYGAGEAALSYHFPERNRIIAGLSRGVLVVEAKQRSGSLITCQLAMEEGR
DIFVVPDNILNGTSAGCLKLIKDGASCVTHGRDILSEYHYS

Nucleotide

• Length: 846 bp

>NTDB_id=506425 I2434_RS04830 WP_012677974.1 1025864..1026709(+) (dprA) [Streptococcus equi subsp. zooepidemicus strain SEZ18]
ATGAACAATTTTGAACTTTATAAATTAAAAAAGGCTGGGCTGACTAATTTAAATATTCTTAACCTGATTGACTACCAGCA
GCGTAATAACAAGTCTCTATCCCTTAGAGATATAGCAGTGGTTTCTTGCTGCAAAAATCCAGTTTTATTTATTGAGACCT
ACAAGCAATTAAATGTCGCCTTGTTAAAAAAGGAATTCAATCAGTTTCCGAGCTTATCTATCCTAGATAAGCAATACCCA
TTGGCTCTGAGGGAAATCTACAATCCTCCTGTTTTACTCTTTTATCAAGGTGATTTAAGCCTGTTAGAAAAACCTAAGCT
GGCAGTCGTTGGCTCTAGAGAATCCAGTGAAATTGGGACGCGGTCTGTTTATAAAATCATTAAAGAGCTTAAGAATCACT
TTGTCATTGTCAGCGGGCTTGCTAGAGGTATTGATACCAGTGCTCATCTCGCTTGCTTGAAAGCAGGTGGGCAAACCATA
GCTGTTATCGGGACTGGCCTAGATCGCTACTATCCAAAGGAAAATCACCAGCTACAGGAGTTTTTATCTCAGCGTCATCT
CGTGCTCAGTGAATATGGGGCTGGAGAGGCCGCCTTGTCTTATCATTTCCCTGAAAGAAACCGTATTATCGCAGGTCTTA
GTCGAGGTGTCCTTGTTGTTGAGGCTAAGCAGCGCTCTGGCTCTTTGATTACCTGTCAGCTAGCTATGGAAGAGGGACGT
GATATTTTTGTCGTACCTGACAATATTCTTAATGGGACATCGGCGGGCTGTTTGAAGCTGATCAAAGATGGTGCCAGCTG
TGTCACTCATGGCAGAGACATTCTTTCAGAATACCACTATTCTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-61)

• DNA recombination-mediator protein A (DNA_processg_A) (71-269)

3D structure

• AlphaFold DB: A0A6M1KS91

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	68.571	99.644	0.683
dprA/cilB/dalA	Streptococcus mitis SK321	59.643	99.644	0.594
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.286	99.644	0.591
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	58.929	99.644	0.587
dprA	Lactococcus lactis subsp. cremoris KW2	56.584	100	0.566
dprA	Bacillus subtilis subsp. subtilis str. 168	42.4	88.968	0.377