Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   I2433_RS05455 Genome accession   NZ_CP065056
Coordinates   1120753..1121427 (-) Length   224 a.a.
NCBI ID   WP_021320708.1    Uniprot ID   A0AAW3GMV5
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ14     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1115753..1126427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2433_RS05425 (JDBNIEOD_01087) - 1116044..1116304 (-) 261 WP_012515553.1 hypothetical protein -
  I2433_RS05430 (JDBNIEOD_01088) - 1116301..1116684 (-) 384 WP_041790456.1 hypothetical protein -
  I2433_RS05435 (JDBNIEOD_01089) - 1116855..1117100 (-) 246 WP_206151899.1 hypothetical protein -
  I2433_RS05440 (JDBNIEOD_01090) - 1117101..1117520 (-) 420 WP_206151900.1 hypothetical protein -
  I2433_RS05445 (JDBNIEOD_01091) - 1117918..1119315 (+) 1398 WP_206151901.1 ISNCY-like element ISSeq2 family transposase -
  I2433_RS05450 (JDBNIEOD_01092) ciaH 1119450..1120760 (-) 1311 WP_012515549.1 HAMP domain-containing sensor histidine kinase Regulator
  I2433_RS05455 (JDBNIEOD_01093) ciaR 1120753..1121427 (-) 675 WP_021320708.1 response regulator Regulator
  I2433_RS05460 (JDBNIEOD_01094) - 1121846..1124383 (-) 2538 WP_043983578.1 M1 family metallopeptidase -
  I2433_RS05465 (JDBNIEOD_01095) phoU 1124617..1125270 (-) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  I2433_RS05470 (JDBNIEOD_01096) pstB 1125341..1126099 (-) 759 WP_012678019.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25569.58 Da        Isoelectric Point: 4.5644

>NTDB_id=506374 I2433_RS05455 WP_021320708.1 1120753..1121427(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
MIKLLLVEDDLSLSNSIFDFLDDFADVTQVFDGDEGLYEAESGIYDLILLDLMLPEKDGFQVLKALREKDIKIPVLIMTA
KESIDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRVGKFNDKSLKFGNLTVDTTRKEVQVNGQVIELLGKELDLLIY
ILQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTDFVNHLQTLRSVGYILKANE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=506374 I2433_RS05455 WP_021320708.1 1120753..1121427(-) (ciaR) [Streptococcus equi subsp. zooepidemicus strain SEZ14]
ATGATAAAACTATTATTAGTAGAAGACGATTTAAGCTTATCAAATTCCATCTTTGATTTTTTAGATGACTTTGCTGATGT
GACCCAGGTTTTTGATGGCGACGAAGGACTCTATGAGGCAGAAAGCGGCATTTATGATTTGATTCTGTTAGATTTGATGC
TGCCTGAAAAGGATGGCTTTCAAGTGCTAAAGGCCTTACGTGAAAAAGACATCAAAATTCCCGTCTTGATCATGACTGCC
AAAGAAAGCATTGATGACAAGGGACATGGCTTTGAGCTTGGTGCTGATGACTATTTAACCAAGCCCTTTTACCTAGAGGA
ATTAAAAATGCGGATTCAGGCCTTGCTTAAGCGCGTAGGAAAGTTTAATGATAAGAGCCTTAAATTTGGCAACCTGACTG
TAGATACTACCCGTAAAGAGGTACAGGTCAATGGGCAGGTCATAGAGCTATTAGGCAAGGAGCTTGATTTACTAATCTAT
ATCCTTCAAAATCAAAATGTTATTTTGCCAAAGTCACAAATTTTTGATCGTATCTGGGGCTTTGATAGTGATACCACTAT
CTCTGTTGTAGAGGTCTATGTCTCTAAAATCCGTAAGAAGCTTAAGGGGACAGACTTTGTTAATCATCTTCAAACCTTGA
GAAGTGTAGGATATATCTTAAAAGCTAATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

84.615

98.661

0.835
  ciaR Streptococcus pneumoniae Rx1

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae D39

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae R6

80.543

98.661

0.795
  ciaR Streptococcus pneumoniae TIGR4

80.543

98.661

0.795
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.865

100

0.397