Detailed information    

insolico Bioinformatically predicted

Overview


Name   comC/comC2   Type   Regulator
Locus tag   I6L84_RS00235 Genome accession   NZ_CP077224
Coordinates   51259..51411 (+) Length   50 a.a.
NCBI ID   WP_008808033.1    Uniprot ID   P72443
Organism   Streptococcus gordonii strain FDAARGOS 1454     
Function   binding to ComD; induce autophosphorylation of ComD (predicted from homology)   
Competence regulation

Genomic Context


Location: 46259..56411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6L84_RS00210 (I6L84_00210) dnaA 46720..48072 (-) 1353 WP_008808037.1 chromosomal replication initiator protein DnaA -
  I6L84_RS00215 (I6L84_00215) spo0J 48276..49040 (-) 765 WP_045772585.1 ParB/RepB/Spo0J family partition protein Regulator
  I6L84_RS00220 (I6L84_00220) htrA 49106..50299 (-) 1194 WP_060553296.1 S1C family serine protease Regulator
  I6L84_RS00225 (I6L84_00225) rlmH 50493..50972 (+) 480 WP_060553297.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  I6L84_RS00235 (I6L84_00235) comC/comC2 51259..51411 (+) 153 WP_008808033.1 bacteriocin Regulator
  I6L84_RS00240 (I6L84_00240) comD/comD2 51427..52785 (+) 1359 WP_060553298.1 competence system sensor histidine kinase ComD Regulator
  I6L84_RS00245 (I6L84_00245) comE/comE2 52782..53549 (+) 768 WP_008808031.1 competence system response regulator transcription factor ComE Regulator
  I6L84_RS00260 (I6L84_00260) ychF 53871..54986 (+) 1116 WP_008808030.1 redox-regulated ATPase YchF -
  I6L84_RS00265 (I6L84_00265) pth 55060..55629 (+) 570 WP_060553299.1 aminoacyl-tRNA hydrolase -

Sequence


Protein


Download         Length: 50 a.a.        Molecular weight: 6133.22 Da        Isoelectric Point: 11.2092

>NTDB_id=505745 I6L84_RS00235 WP_008808033.1 51259..51411(+) (comC/comC2) [Streptococcus gordonii strain FDAARGOS 1454]
MKKKNKQNLLPKELQQFEILTERKLEQVTGGDIRHRINNSIWRDIFLKRK

Nucleotide


Download         Length: 153 bp        

>NTDB_id=505745 I6L84_RS00235 WP_008808033.1 51259..51411(+) (comC/comC2) [Streptococcus gordonii strain FDAARGOS 1454]
ATGAAAAAGAAAAACAAACAAAATCTATTGCCAAAAGAGTTACAACAATTTGAAATTTTGACAGAAAGAAAATTAGAGCA
AGTTACTGGTGGAGATATTCGACATAGGATTAATAATTCAATTTGGAGAGATATTTTTTTAAAAAGAAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB P72443

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comC/comC2 Streptococcus gordonii strain NCTC7865

100

100

1

  comC/comC1 Streptococcus gordonii str. Challis substr. CH1

74

100

0.74