Detailed information NTG0050532

Bioinformatically predicted

Overview

• Name: comB9
• Type: Machinery gene
• Locus tag: HPSH112_RS00220
• Genome accession: NC_017741
• Coordinates: 36377..37333 (+)
• Length: 318 a.a.
• NCBI ID: WP_014662053.1
• Uniprot ID: A0A0E0W9D0
• Organism: Helicobacter pylori Shi112
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 31377..42333

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPSH112_RS00190 (HPSH112_00165)	panD	32798..33148 (+)	351	WP_000142269.1	aspartate 1-decarboxylase	-
HPSH112_RS00195 (HPSH112_00170)	-	33159..33452 (+)	294	WP_000347917.1	YbaB/EbfC family nucleoid-associated protein	-
HPSH112_RS00200 (HPSH112_00175)	-	33452..34447 (+)	996	WP_000468441.1	PDZ domain-containing protein	-
HPSH112_RS00205 (HPSH112_00180)	comB6	34453..35508 (+)	1056	WP_000786694.1	P-type conjugative transfer protein TrbL	Machinery gene
HPSH112_RS00210	comB7	35524..35637 (+)	114	WP_001217864.1	hypothetical protein	Machinery gene
HPSH112_RS00215 (HPSH112_00185)	comB8	35634..36377 (+)	744	WP_000660502.1	type IV secretion system protein	Machinery gene
HPSH112_RS00220 (HPSH112_00190)	comB9	36377..37333 (+)	957	WP_014662053.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HPSH112_RS00225 (HPSH112_00195)	comB10	37326..38462 (+)	1137	WP_001045868.1	DNA type IV secretion system protein ComB10	Machinery gene
HPSH112_RS00230 (HPSH112_00200)	-	38534..39946 (+)	1413	WP_000694836.1	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
HPSH112_RS00235 (HPSH112_00205)	gmd	39961..41106 (+)	1146	WP_000659844.1	GDP-mannose 4,6-dehydratase	-
HPSH112_RS00240 (HPSH112_00210)	-	41099..42031 (+)	933	WP_001002520.1	GDP-L-fucose synthase family protein	-

Sequence

Protein

• Length: 318 a.a.
• Molecular weight: 36505.00 Da
• Isoelectric Point: 9.4680

>NTDB_id=50532 HPSH112_RS00220 WP_014662053.1 36377..37333(+) (comB9) [Helicobacter pylori Shi112]
MRKVLYALVGFLLAFSALKADDFLEEANETAPANLNHPMQDLNAIQGSFFDKNRSKMSNTLNIDYFQGQTYKIRLRYAMA
TLLFFSKPISDFVLGDKVGFDAKILESNDRILLIKPLQIGVDSNVSVIDNEGKIFSFYVFSTTFTSSKHPNLQVFIEDKN
YYSNAFMKPQNKENTLENTPTNNSKPLKEETKEEETITIGDSTNAMKIVKKDIQKGYRALKSSQRKWYCLGICSKKSKLS
LMPEEIFNDKQFTYFKFDKKLALSKFPVIYKVVDGYDNPVNTRIVGDYIIAEDVSAKWTLRLGKDYLCIRFIKKGKDE

Nucleotide

• Length: 957 bp

>NTDB_id=50532 HPSH112_RS00220 WP_014662053.1 36377..37333(+) (comB9) [Helicobacter pylori Shi112]
ATGCGTAAGGTTTTATACGCTCTTGTGGGCTTTTTGTTGGCTTTTAGCGCTTTAAAAGCCGATGATTTTTTAGAAGAAGC
TAACGAAACAGCCCCGGCGAATTTAAACCACCCCATGCAAGATTTAAACGCCATTCAAGGGAGCTTTTTTGACAAGAACC
GCTCAAAAATGTCCAACACTTTGAACATTGATTACTTTCAAGGGCAAACCTATAAAATCCGCTTGCGTTATGCGATGGCG
ACCTTATTGTTTTTTTCAAAACCCATTAGCGATTTTGTTTTAGGGGATAAGGTGGGCTTTGATGCGAAAATCTTAGAAAG
TAACGATCGCATTTTGCTCATCAAACCCCTACAAATTGGCGTGGATTCTAATGTCAGCGTGATTGATAATGAGGGTAAGA
TTTTTTCTTTCTATGTGTTTTCTACCACTTTCACTAGCTCCAAACACCCTAATTTACAGGTTTTCATAGAAGATAAAAAC
TATTATTCCAACGCTTTTATGAAGCCACAAAACAAAGAAAATACCCTTGAAAATACCCCCACAAACAACAGCAAACCCTT
AAAAGAAGAAACCAAAGAAGAAGAGACTATAACGATTGGCGATAGCACTAATGCGATGAAAATCGTTAAAAAAGACATTC
AAAAAGGCTATAGGGCTTTAAAAAGCTCTCAAAGGAAATGGTATTGTTTGGGGATTTGTTCTAAAAAATCCAAACTCTCT
TTGATGCCTGAAGAAATTTTTAACGACAAGCAATTCACTTATTTCAAATTTGACAAAAAATTAGCGCTCTCTAAATTCCC
GGTGATTTATAAAGTCGTTGATGGCTATGATAACCCGGTGAATACTAGGATTGTGGGCGATTACATTATCGCTGAAGATG
TCTCGGCTAAATGGACTTTAAGGCTGGGTAAGGACTATTTGTGTATCCGTTTTATCAAAAAGGGTAAAGATGAATAA

Domains

Predicted by InterproScan.

• Conjugal transfer protein (CagX) (62-309)

3D structure

• AlphaFold DB: A0A0E0W9D0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB9	Helicobacter pylori P1	92.966	100	0.956