Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KQ221_RS02160 Genome accession   NZ_CP076704
Coordinates   443910..445034 (+) Length   374 a.a.
NCBI ID   WP_000228538.1    Uniprot ID   -
Organism   Escherichia coli O8:H28 strain BMH-17-0027     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 438910..450034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ221_RS02135 (KQ221_02135) mscL 439036..439446 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  KQ221_RS02140 (KQ221_02140) trkA 439576..440952 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  KQ221_RS02145 (KQ221_02145) rsmB 440974..442263 (-) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KQ221_RS02150 (KQ221_02150) fmt 442309..443256 (-) 948 WP_000004451.1 methionyl-tRNA formyltransferase -
  KQ221_RS02155 (KQ221_02155) def 443271..443780 (-) 510 WP_000114984.1 peptide deformylase -
  KQ221_RS02160 (KQ221_02160) dprA 443910..445034 (+) 1125 WP_000228538.1 DNA-protecting protein DprA Machinery gene
  KQ221_RS02165 (KQ221_02165) smg 445006..445479 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  KQ221_RS02170 (KQ221_02170) yrdD 445508..446050 (+) 543 WP_001129719.1 type I DNA topoisomerase -
  KQ221_RS02175 (KQ221_02175) tsaC 446055..446627 (+) 573 WP_001365949.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  KQ221_RS02180 (KQ221_02180) aroE 446632..447450 (+) 819 WP_000451211.1 shikimate dehydrogenase -
  KQ221_RS02185 (KQ221_02185) yrdB 447447..447704 (+) 258 WP_001070563.1 DUF1488 domain-containing protein -
  KQ221_RS02190 (KQ221_02190) yrdA 447680..448234 (-) 555 WP_001286216.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40955.86 Da        Isoelectric Point: 6.3122

>NTDB_id=504122 KQ221_RS02160 WP_000228538.1 443910..445034(+) (dprA) [Escherichia coli O8:H28 strain BMH-17-0027]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=504122 KQ221_RS02160 WP_000228538.1 443910..445034(+) (dprA) [Escherichia coli O8:H28 strain BMH-17-0027]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

45.135

98.93

0.447
  dprA Vibrio cholerae strain A1552

45.135

98.93

0.447
  dprA Haemophilus influenzae Rd KW20

45.401

90.107

0.409
  dprA Glaesserella parasuis strain SC1401

45.133

90.642

0.409
  dprA Legionella pneumophila strain ERS1305867

44.848

88.235

0.396