Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvB   Type   Machinery gene
Locus tag   SCRE_RS00420 Genome accession   NC_022236
Coordinates   68361..69359 (+) Length   332 a.a.
NCBI ID   WP_020997528.1    Uniprot ID   U2ZMX9
Organism   Streptococcus constellatus subsp. pharyngis C232     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 63361..74359
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCRE_RS00385 - 64414..64593 (-) 180 WP_022525545.1 hypothetical protein -
  SCRE_RS00390 (SCRE_0078) - 64706..65488 (-) 783 WP_006269197.1 aminoglycoside N(3)-acetyltransferase -
  SCRE_RS00395 (SCRE_0079) - 65549..65986 (-) 438 WP_020997525.1 GNAT family N-acetyltransferase -
  SCRE_RS00400 (SCRE_0080) - 65986..66426 (-) 441 WP_037592430.1 hypothetical protein -
  SCRE_RS00405 (SCRE_0081) - 66539..67189 (-) 651 WP_020997527.1 ABC-2 transporter permease -
  SCRE_RS00410 (SCRE_0082) - 67189..67923 (-) 735 WP_148290520.1 ABC transporter ATP-binding protein -
  SCRE_RS00415 (SCRE_0083) - 67925..68140 (-) 216 WP_006269106.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
  SCRE_RS00420 (SCRE_0084) ruvB 68361..69359 (+) 999 WP_020997528.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  SCRE_RS00425 (SCRE_0085) - 69365..69933 (+) 569 Protein_65 nucleotidyltransferase family protein -
  SCRE_RS00430 (SCRE_0086) - 70173..70601 (+) 429 WP_003036965.1 low molecular weight protein-tyrosine-phosphatase -
  SCRE_RS00435 (SCRE_0087) - 70610..71023 (+) 414 WP_003036952.1 MORN repeat-containing protein -
  SCRE_RS00440 (SCRE_0088) - 71013..72830 (+) 1818 WP_020997529.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 332 a.a.        Molecular weight: 37304.69 Da        Isoelectric Point: 4.4354

>NTDB_id=50361 SCRE_RS00420 WP_020997528.1 68361..69359(+) (ruvB) [Streptococcus constellatus subsp. pharyngis C232]
MSRILDNELMGDEELVERTLRPQYLQEYIGQDKVKNQLKIFIEAAKLRDEALDHTLLFGPPGLGKTTMAFVIANELGVNL
KQTSGPVIEKAGDLVAILNDLDPGDVLFIDEIHRLPMAVEEVLYSAMEDFYIDIMIGAGETSRSVHLELPPFTLIGATTR
AGMLSNPLRARFGITGHMEYYAEADLTEIVERTAEIFEMDITHEAAEELALRSRGTPRIANRLLKRVRDFAQIMGDGLID
AHITDQALSMLDVDQEGLDYVDQKILKTMIEVYGGGPVGLGTLSVNIAEERETVEDMYEPYLIQKGFVMRTRTGRVATRK
AYEHLGYEYFEK

Nucleotide


Download         Length: 999 bp        

>NTDB_id=50361 SCRE_RS00420 WP_020997528.1 68361..69359(+) (ruvB) [Streptococcus constellatus subsp. pharyngis C232]
ATGAGTAGAATTTTAGATAATGAATTGATGGGAGACGAAGAGTTAGTAGAACGCACGCTTCGTCCCCAGTATTTGCAAGA
ATATATTGGGCAAGATAAGGTCAAAAATCAATTAAAGATTTTTATTGAGGCAGCTAAGTTGCGAGATGAGGCGCTAGATC
ACACCTTGCTTTTCGGACCTCCGGGACTAGGGAAGACCACTATGGCCTTTGTTATTGCCAATGAACTAGGAGTCAATCTC
AAGCAAACTTCTGGTCCAGTCATCGAAAAAGCAGGTGATTTGGTAGCGATTTTAAATGACCTAGATCCGGGAGATGTCCT
CTTTATTGATGAAATTCATCGCTTACCCATGGCTGTGGAAGAAGTACTTTACAGCGCGATGGAGGATTTCTATATTGACA
TCATGATTGGTGCAGGGGAGACCAGCCGTAGCGTTCACTTGGAGTTGCCGCCTTTTACGCTGATTGGAGCAACGACGCGG
GCAGGTATGCTGTCAAATCCTCTACGCGCACGTTTCGGGATTACTGGTCACATGGAATATTATGCAGAAGCAGATTTGAC
TGAGATTGTGGAGCGAACGGCAGAAATTTTTGAAATGGATATCACTCATGAAGCAGCTGAGGAATTGGCACTGCGCAGCC
GGGGTACGCCTCGGATTGCCAATCGGCTTCTTAAACGCGTACGAGATTTTGCTCAAATCATGGGAGATGGTTTGATTGAT
GCTCATATCACTGATCAGGCTTTATCAATGCTGGACGTGGATCAAGAAGGGCTGGATTATGTAGATCAGAAGATTCTTAA
AACCATGATTGAGGTTTATGGTGGTGGTCCGGTTGGTCTGGGAACTCTTTCGGTTAATATCGCTGAAGAACGAGAAACAG
TTGAAGATATGTATGAGCCTTATCTGATCCAAAAAGGCTTTGTCATGCGGACGAGAACAGGGCGCGTGGCGACCCGCAAG
GCTTATGAACATCTAGGTTATGAGTATTTTGAAAAGTAG

Domains

Predicted by InterProScan.

RuvB AAA lid domain (AAA_lid_4)

(181-254)

Holliday junction DNA helicase RuvB P-loop domain (RuvB_N)

(20-178)

RuvB C-terminal winged helix domain (WHD_RuvB)

(256-325)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB U2ZMX9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvB Streptococcus pneumoniae TIGR4

91.867

100

0.919
  ruvB Streptococcus pneumoniae R6

91.566

100

0.916
  ruvB Streptococcus pneumoniae D39

91.566

100

0.916
  ruvB Bacillus subtilis subsp. subtilis str. 168

58.589

98.193

0.575
  ruvB Helicobacter pylori 26695

51.393

97.289

0.5
  ruvB Synechocystis sp. PCC 6803

50.323

93.373

0.47

Multiple sequence alignment