Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   A7A19_RS18620 Genome accession   NZ_CP076279
Coordinates   3740594..3741718 (-) Length   374 a.a.
NCBI ID   WP_000228519.1    Uniprot ID   -
Organism   Escherichia coli strain SA53-3     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3735594..3746718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A19_RS18590 (A7A19_18545) yrdA 3737394..3737948 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  A7A19_RS18595 (A7A19_18550) yrdB 3737924..3738181 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  A7A19_RS18600 (A7A19_18555) aroE 3738178..3738996 (-) 819 WP_000451211.1 shikimate dehydrogenase -
  A7A19_RS18605 (A7A19_18560) tsaC 3739001..3739573 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  A7A19_RS18610 (A7A19_18565) yrdD 3739578..3740120 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  A7A19_RS18615 (A7A19_18570) smg 3740149..3740622 (-) 474 WP_257122638.1 DUF494 family protein Smg -
  A7A19_RS18620 (A7A19_18575) dprA 3740594..3741718 (-) 1125 WP_000228519.1 DNA-protecting protein DprA Machinery gene
  A7A19_RS18625 (A7A19_18580) def 3741848..3742357 (+) 510 WP_000114984.1 peptide deformylase -
  A7A19_RS18630 (A7A19_18585) fmt 3742372..3743319 (+) 948 WP_000004432.1 methionyl-tRNA formyltransferase -
  A7A19_RS18635 (A7A19_18590) rsmB 3743365..3744654 (+) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A7A19_RS18640 (A7A19_18595) trkA 3744676..3746052 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  A7A19_RS18645 (A7A19_18600) mscL 3746182..3746592 (+) 411 WP_000022439.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41006.95 Da        Isoelectric Point: 6.3839

>NTDB_id=501760 A7A19_RS18620 WP_000228519.1 3740594..3741718(-) (dprA) [Escherichia coli strain SA53-3]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=501760 A7A19_RS18620 WP_000228519.1 3740594..3741718(-) (dprA) [Escherichia coli strain SA53-3]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT
TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Haemophilus influenzae Rd KW20

45.401

90.107

0.409
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

49.355

82.888

0.409
  dprA Vibrio cholerae strain A1552

49.355

82.888

0.409
  dprA Glaesserella parasuis strain SC1401

45.104

90.107

0.406
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393