Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   A7A21_RS17995 Genome accession   NZ_CP076276
Coordinates   3667189..3668313 (-) Length   374 a.a.
NCBI ID   WP_021554566.1    Uniprot ID   -
Organism   Escherichia coli strain SA31-1     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 3662189..3673313
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7A21_RS17965 (A7A21_17910) yrdA 3663989..3664543 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  A7A21_RS17970 (A7A21_17915) yrdB 3664519..3664776 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  A7A21_RS17975 (A7A21_17920) aroE 3664773..3665591 (-) 819 WP_000451211.1 shikimate dehydrogenase -
  A7A21_RS17980 (A7A21_17925) tsaC 3665596..3666168 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  A7A21_RS17985 (A7A21_17930) yrdD 3666173..3666715 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  A7A21_RS17990 (A7A21_17935) smg 3666744..3667217 (-) 474 WP_000460670.1 DUF494 family protein Smg -
  A7A21_RS17995 (A7A21_17940) dprA 3667189..3668313 (-) 1125 WP_021554566.1 DNA-protecting protein DprA Machinery gene
  A7A21_RS18000 (A7A21_17945) def 3668443..3668952 (+) 510 WP_000114984.1 peptide deformylase -
  A7A21_RS18005 (A7A21_17950) fmt 3668967..3669914 (+) 948 WP_021554567.1 methionyl-tRNA formyltransferase -
  A7A21_RS18010 (A7A21_17955) rsmB 3669960..3671249 (+) 1290 WP_000744779.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  A7A21_RS18015 (A7A21_17960) trkA 3671271..3672647 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  A7A21_RS18020 (A7A21_17965) mscL 3672777..3673187 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40971.86 Da        Isoelectric Point: 6.3122

>NTDB_id=501682 A7A21_RS17995 WP_021554566.1 3667189..3668313(-) (dprA) [Escherichia coli strain SA31-1]
MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLQATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=501682 A7A21_RS17995 WP_021554566.1 3667189..3668313(-) (dprA) [Escherichia coli strain SA31-1]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGGCGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.509

98.663

0.479
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

44.865

98.93

0.444
  dprA Vibrio cholerae strain A1552

44.865

98.93

0.444
  dprA Glaesserella parasuis strain SC1401

44.838

90.642

0.406
  dprA Haemophilus influenzae Rd KW20

45.104

90.107

0.406
  dprA Legionella pneumophila strain ERS1305867

44.545

88.235

0.393