NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	A7A11_RS18550	Genome accession	NZ_CP076272
Coordinates	3759048..3760172 (-)	Length	374 a.a.
NCBI ID	WP_000228531.1	Uniprot ID	A7ZSH4
Organism	Escherichia coli strain E21845/O/A
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3754048..3765172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7A11_RS18520	yrdA	3755848..3756402 (+)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
A7A11_RS18525	yrdB	3756378..3756635 (-)	258	WP_001070563.1	DUF1488 domain-containing protein	-
A7A11_RS18530	aroE	3756632..3757450 (-)	819	WP_000451211.1	shikimate dehydrogenase	-
A7A11_RS18535	tsaC	3757455..3758027 (-)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
A7A11_RS18540	yrdD	3758032..3758574 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
A7A11_RS18545	smg	3758603..3759076 (-)	474	WP_000460672.1	DUF494 family protein Smg	-
A7A11_RS18550	dprA	3759048..3760172 (-)	1125	WP_000228531.1	DNA-protecting protein DprA	Machinery gene
A7A11_RS18555	def	3760302..3760811 (+)	510	WP_000114984.1	peptide deformylase	-
A7A11_RS18560	fmt	3760826..3761773 (+)	948	WP_000004432.1	methionyl-tRNA formyltransferase	-
A7A11_RS18565	rsmB	3761819..3763108 (+)	1290	WP_000744779.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
A7A11_RS18570	trkA	3763130..3764506 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
A7A11_RS18575	mscL	3764636..3765046 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40986.98 Da Isoelectric Point: 6.3122

                                >NTDB_id=501523 A7A11_RS18550 WP_000228531.1 3759048..3760172(-) (dprA) [Escherichia coli strain E21845/O/A]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLMTTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=501523 A7A11_RS18550 WP_000228531.1 3759048..3760172(-) (dprA) [Escherichia coli strain E21845/O/A]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGATGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCTGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTCTGCT

TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A7ZSH4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	44.865	98.93	0.444
dprA	Vibrio cholerae strain A1552	44.865	98.93	0.444
dprA	Haemophilus influenzae Rd KW20	45.401	90.107	0.409
dprA	Glaesserella parasuis strain SC1401	44.838	90.642	0.406
dprA	Legionella pneumophila strain ERS1305867	44.545	88.235	0.393

Detailed information NTG0501523