Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   IUJ46_RS09635 Genome accession   NZ_CP064364
Coordinates   1878149..1878910 (+) Length   253 a.a.
NCBI ID   WP_002986029.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain PartK-Spyogenes-RM8376     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1873149..1883910
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IUJ46_RS09620 (IUJ46_09570) - 1873434..1875002 (-) 1569 WP_011285384.1 ABC transporter substrate-binding protein/permease -
  IUJ46_RS09625 (IUJ46_09575) - 1875200..1877098 (+) 1899 WP_010921886.1 DUF2207 domain-containing protein -
  IUJ46_RS09630 (IUJ46_09580) - 1877164..1878003 (+) 840 WP_002986031.1 undecaprenyl-diphosphate phosphatase -
  IUJ46_RS09635 (IUJ46_09585) mecA 1878149..1878910 (+) 762 WP_002986029.1 adaptor protein MecA Regulator
  IUJ46_RS09640 (IUJ46_09590) - 1878917..1880086 (+) 1170 WP_002991122.1 MraY family glycosyltransferase -
  IUJ46_RS09645 (IUJ46_09595) sufC 1880208..1880978 (+) 771 WP_002986023.1 Fe-S cluster assembly ATPase SufC -
  IUJ46_RS09650 (IUJ46_09600) sufD 1881073..1882335 (+) 1263 WP_010921887.1 Fe-S cluster assembly protein SufD -
  IUJ46_RS09655 (IUJ46_09605) - 1882366..1883592 (+) 1227 WP_029714224.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 253 a.a.        Molecular weight: 29051.72 Da        Isoelectric Point: 4.1622

>NTDB_id=501102 IUJ46_RS09635 WP_002986029.1 1878149..1878910(+) (mecA) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
MEMKQISETTLKITISMDDLEERGMELKDFLIPQEKTEEFFYSVMDELDLPDNFKDSGMLSFRVTPRKDRLDVFVTKSEI
NKDINLEDLAEFGDMSQMTPEDFFKSLEQSMREKGDVKAHEKLEKIEEIMEDVVEATLANQSEAADPSTNHESEPLDYVH
YVLDFSTITEAVAFAKTIDFSIEASELYKGSNCYHMTILLDVQQQPSYFANVMYARLIEHANPGSKTRAYLQEHGLQLML
DGAVEQLQKIELG

Nucleotide


Download         Length: 762 bp        

>NTDB_id=501102 IUJ46_RS09635 WP_002986029.1 1878149..1878910(+) (mecA) [Streptococcus pyogenes strain PartK-Spyogenes-RM8376]
ATGGAAATGAAACAAATTAGCGAGACAACGCTAAAAATAACAATTAGTATGGACGATTTAGAAGAAAGAGGAATGGAGTT
GAAAGATTTCTTGATTCCTCAAGAAAAAACAGAAGAGTTTTTCTATTCTGTGATGGACGAACTCGATCTTCCAGATAATT
TTAAAGATAGTGGTATGCTTAGTTTTCGAGTGACTCCACGCAAGGACCGTCTAGATGTTTTTGTTACCAAATCTGAGATA
AATAAAGATATTAATCTTGAAGATTTAGCAGAGTTTGGTGATATGTCCCAAATGACTCCGGAAGATTTTTTCAAGAGCTT
GGAGCAATCCATGCGTGAAAAGGGAGATGTCAAAGCTCATGAAAAATTGGAAAAAATTGAAGAGATAATGGAAGATGTTG
TTGAAGCCACTCTAGCTAATCAGTCTGAGGCGGCTGATCCATCAACTAATCATGAGTCAGAACCTTTAGACTATGTCCAT
TATGTATTGGATTTTTCAACGATTACAGAGGCAGTGGCTTTTGCTAAAACGATTGATTTTTCGATAGAAGCTTCAGAGTT
ATATAAGGGGAGCAACTGCTACCATATGACTATTTTATTAGATGTTCAGCAACAACCATCTTATTTTGCGAACGTCATGT
ATGCGAGATTGATTGAGCATGCAAACCCTGGATCAAAAACAAGAGCTTATTTACAAGAGCATGGCTTACAATTGATGCTT
GATGGTGCTGTTGAGCAATTACAAAAGATTGAGTTGGGATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

63.2

98.814

0.625
  mecA Streptococcus thermophilus LMD-9

56.225

98.419

0.553
  mecA Streptococcus thermophilus LMG 18311

55.422

98.419

0.545
  mecA Streptococcus pneumoniae Rx1

48.235

100

0.486
  mecA Streptococcus pneumoniae D39

48.235

100

0.486
  mecA Streptococcus pneumoniae R6

48.235

100

0.486
  mecA Streptococcus pneumoniae TIGR4

48.235

100

0.486