Detailed information NTG0500664

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: LacP0625_RS12600
• Genome accession: NZ_CP064311
• Coordinates: 2599662..2601854 (-)
• Length: 730 a.a.
• NCBI ID: WP_194957896.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei subsp. tolerans strain MGB0625
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2594662..2606854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LacP0625_RS12570 (LacP0625_12570)	-	2594827..2595111 (-)	285	WP_003580845.1	bacteriocin immunity protein	-
LacP0625_RS12575 (LacP0625_12575)	-	2595305..2595601 (-)	297	WP_194957894.1	bacteriocin immunity protein	-
LacP0625_RS12580 (LacP0625_12580)	-	2595703..2597058 (-)	1356	WP_003567335.1	threonine/serine exporter ThrE family protein	-
LacP0625_RS12585 (LacP0625_12585)	-	2597364..2597675 (-)	312	WP_003580849.1	hypothetical protein	-
LacP0625_RS12590 (LacP0625_12590)	-	2597748..2598098 (-)	351	WP_003567340.1	hypothetical protein	-
LacP0625_RS12595 (LacP0625_12595)	-	2598272..2599651 (-)	1380	WP_194957895.1	bacteriocin secretion accessory protein	-
LacP0625_RS12600 (LacP0625_12600)	comA	2599662..2601854 (-)	2193	WP_194957896.1	peptide cleavage/export ABC transporter	Regulator
LacP0625_RS12605 (LacP0625_12605)	-	2602320..2602460 (-)	141	WP_016384130.1	bacteriocin-like peptide, LSEI_2386 family	-
LacP0625_RS12610 (LacP0625_12610)	-	2602651..2603004 (+)	354	Protein_2487	histidine kinase	-
LacP0625_RS12615 (LacP0625_12615)	-	2603024..2603944 (-)	921	WP_003574021.1	IS30 family transposase	-
LacP0625_RS12620 (LacP0625_12620)	-	2604054..2605004 (+)	951	Protein_2489	GHKL domain-containing protein	-
LacP0625_RS12625 (LacP0625_12625)	-	2605009..2605503 (+)	495	Protein_2490	response regulator	-
LacP0625_RS12630 (LacP0625_12630)	-	2605615..2606535 (+)	921	WP_003574021.1	IS30 family transposase	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81335.57 Da
• Isoelectric Point: 7.0666

>NTDB_id=500664 LacP0625_RS12600 WP_194957896.1 2599662..2601854(-) (comA) [Lacticaseibacillus paracasei subsp. tolerans strain MGB0625]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFHGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALTNTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMLTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHAELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=500664 LacP0625_RS12600 WP_194957896.1 2599662..2601854(-) (comA) [Lacticaseibacillus paracasei subsp. tolerans strain MGB0625]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGCTGCTGCAATTTCATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGAACAACAGCGTTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCTGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTCGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATCACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCTATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGACAAACACGATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTAGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATTTTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGCTGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGACTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTTACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAGCAAATCAATCTTGAAATCCCAGAGAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCCAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGGAAAATCACATTTAATGGGGTTCCAATC
AGTGATGTTGATCTGACAACGTTACGACAATATATCGAGTATGTACCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGATCATGGTGCGATTGTTGAACAAGGAAATCATGCTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (16-152)

• ABC transporter (ABC_tran) (510-662)

• ABC transporter transmembrane region (ABC_membrane) (180-448)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.914	98.356	0.579
comA	Streptococcus pneumoniae Rx1	58.357	98.356	0.574
comA	Streptococcus pneumoniae D39	58.357	98.356	0.574
comA	Streptococcus pneumoniae R6	58.357	98.356	0.574
comA	Streptococcus mitis SK321	58.217	98.356	0.573
comA	Streptococcus pneumoniae TIGR4	57.939	98.356	0.57
comA	Streptococcus gordonii str. Challis substr. CH1	56.964	98.356	0.56
comA/nlmT	Streptococcus mutans UA159	54.848	98.904	0.542