Detailed information NTG0500631

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: LacP0734_RS12460
• Genome accession: NZ_CP064304
• Coordinates: 2559980..2562172 (+)
• Length: 730 a.a.
• NCBI ID: WP_194958408.1
• Uniprot ID: -
• Organism: Lacticaseibacillus paracasei subsp. tolerans strain MGB0734
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2554980..2567172

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LacP0734_RS12425 (LacP0734_12425)	-	2555073..2555246 (+)	174	WP_194958404.1	hypothetical protein	-
LacP0734_RS12430 (LacP0734_12430)	-	2555285..2555458 (+)	174	WP_013246049.1	bacteriocin	-
LacP0734_RS12435 (LacP0734_12435)	-	2555732..2555971 (-)	240	WP_194958405.1	hypothetical protein	-
LacP0734_RS12440 (LacP0734_12440)	-	2556518..2556715 (+)	198	WP_194958406.1	hypothetical protein	-
LacP0734_RS12445 (LacP0734_12445)	-	2557077..2557883 (-)	807	WP_003567351.1	LytR/AlgR family response regulator transcription factor	-
LacP0734_RS12450 (LacP0734_12450)	-	2557888..2559186 (-)	1299	WP_194958407.1	GHKL domain-containing protein	-
LacP0734_RS12455 (LacP0734_12455)	-	2559376..2559513 (+)	138	WP_003571414.1	bacteriocin-like peptide, LSEI_2386 family	-
LacP0734_RS12460 (LacP0734_12460)	comA	2559980..2562172 (+)	2193	WP_194958408.1	peptide cleavage/export ABC transporter	Regulator
LacP0734_RS12465 (LacP0734_12465)	-	2562183..2563562 (+)	1380	WP_194958409.1	bacteriocin secretion accessory protein	-
LacP0734_RS12470 (LacP0734_12470)	-	2563736..2564086 (+)	351	WP_003567340.1	hypothetical protein	-
LacP0734_RS12475 (LacP0734_12475)	-	2564159..2564470 (+)	312	WP_194958410.1	hypothetical protein	-
LacP0734_RS12480 (LacP0734_12480)	-	2564776..2566131 (+)	1356	WP_003567335.1	threonine/serine exporter ThrE family protein	-
LacP0734_RS12485 (LacP0734_12485)	-	2566233..2566529 (+)	297	WP_003588783.1	bacteriocin immunity protein	-
LacP0734_RS12490 (LacP0734_12490)	-	2566722..2567006 (+)	285	WP_063557690.1	bacteriocin immunity protein	-

Sequence

Protein

• Length: 730 a.a.
• Molecular weight: 81330.57 Da
• Isoelectric Point: 7.0227

>NTDB_id=500631 LacP0734_RS12460 WP_194958408.1 2559980..2562172(+) (comA) [Lacticaseibacillus paracasei subsp. tolerans strain MGB0734]
MIKYNLKLGQAQYYKRYYTPQVDERDCGVAALNMLLQFNGSDYSLAHLRQLAKTDQEGTTALGIVRAAQALHFETKAVKA
DMTLFDLDDVPYPFLVHVLKRGELLHYYVVFKATKDHILIGDPDPSVAMTWLPKERFAKEWSGVAIFIAPEPQYQPRKED
KGSLFAFVPILARQKGIIANIIVAAVLITLISIVGSYFLQSIIDTYIPNGMRTTLGMIASGLILAYVLQSVLTYGQNFLM
AVLGQRLSIDVILGYVRHLYELPMSFFSTRRTGEIVSRFSDANKIIDALANTIMTLFLDIWIVLILGIVLGIQNTTLFLV
SLIAVPCYLVIVFAFQRPFNRLNQETMESNAILSSSIIEDLNGIETIKSLTGEKVSYERVDREFVTYLKKSFNYTKADQL
QQAIKGLLKLVLNVVVLWIGASLVMANKMSLGQMMTFNALLAYFTNPLESIINLQPKLQMAKVANNRLNEVYLVESEFKE
QRSLNDRHLIDGAINVTDVSFKYGFGQDVLKQINLEIPENAKYTIVGMSGSGKSTLAKLLVGFYPVDTGKGKITFNGVPI
SDVDLTTLRQYIEYVPQDPFIFSGSVIENLTLGSRSNITEADIEAACSVAEIAGDISNLPQIWQTKLSESGSILSGGQKQ
RLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIAAKTEQIVVMDHGAIVEQGNHTELLAK
QGYYARLVSE

Nucleotide

• Length: 2193 bp

>NTDB_id=500631 LacP0734_RS12460 WP_194958408.1 2559980..2562172(+) (comA) [Lacticaseibacillus paracasei subsp. tolerans strain MGB0734]
ATGATCAAATACAACCTAAAGCTCGGCCAAGCACAGTATTACAAGCGTTACTACACGCCTCAGGTGGATGAGCGCGATTG
CGGGGTTGCGGCGCTTAATATGTTGCTGCAATTTAATGGCTCGGATTATTCGCTAGCGCATCTGCGACAGTTGGCGAAGA
CGGATCAGGAAGGGACGACGGCATTAGGGATTGTCCGCGCTGCTCAGGCGCTTCATTTTGAAACCAAGGCGGTCAAGGCG
GATATGACGCTGTTTGATCTTGATGATGTTCCTTATCCGTTTCTTGTCCATGTTTTGAAGCGTGGCGAGTTGCTTCATTA
TTATGTGGTGTTTAAGGCGACAAAGGATCATATCTTGATTGGCGATCCTGATCCATCAGTAGCGATGACCTGGCTTCCCA
AAGAGCGCTTTGCGAAGGAGTGGTCGGGGGTCGCTATTTTTATTGCGCCAGAACCGCAATATCAACCACGCAAAGAGGAC
AAAGGCAGTCTCTTTGCGTTTGTGCCGATACTAGCGCGACAAAAAGGGATCATTGCCAATATTATTGTCGCCGCTGTGTT
GATTACGTTGATTAGTATTGTCGGGTCTTATTTTCTTCAGTCGATTATTGATACTTATATTCCAAACGGGATGCGCACAA
CTTTGGGAATGATTGCCAGTGGTCTCATCCTTGCTTATGTCCTGCAGTCGGTTTTAACCTATGGGCAAAATTTTTTGATG
GCTGTTTTAGGACAGCGTTTGTCGATTGATGTCATTTTGGGTTACGTTAGGCATCTTTATGAATTACCGATGTCCTTCTT
TTCCACGCGTCGGACTGGGGAGATTGTATCGCGGTTTTCCGATGCTAATAAGATTATTGATGCGCTGGCAAACACAATTA
TGACCTTGTTTCTTGATATTTGGATTGTCTTAATTTTAGGGATCGTGTTAGGCATTCAAAACACCACCTTATTCTTGGTG
TCTTTAATTGCTGTGCCTTGTTATTTGGTGATTGTGTTCGCTTTTCAGCGGCCATTTAATCGACTGAATCAAGAGACGAT
GGAAAGCAATGCCATATTGAGTTCATCCATTATCGAGGATTTGAACGGGATTGAGACGATTAAATCACTGACCGGTGAGA
AAGTCAGTTATGAACGGGTTGACCGTGAATTCGTCACGTATTTGAAAAAGTCGTTCAATTATACAAAAGCTGATCAACTG
CAGCAGGCGATCAAGGGACTGCTGAAGTTGGTTTTGAATGTGGTCGTGCTGTGGATTGGTGCGAGTTTGGTGATGGCTAA
CAAGATGAGTCTAGGACAGATGATGACGTTCAATGCGTTGTTGGCATATTTCACTAATCCGTTAGAAAGCATCATTAATT
TGCAACCAAAATTGCAAATGGCCAAAGTCGCGAATAACCGGCTGAATGAAGTGTATTTGGTTGAATCGGAGTTTAAAGAA
CAGCGAAGTTTGAATGATCGGCATTTAATTGATGGCGCCATCAATGTGACCGATGTGTCCTTTAAGTATGGTTTTGGGCA
AGATGTTTTGAAACAAATCAACCTTGAAATCCCGGAAAATGCCAAATACACCATTGTCGGCATGAGTGGATCAGGGAAAT
CGACCTTAGCTAAGTTGCTAGTAGGTTTCTATCCAGTGGACACTGGCAAAGGAAAAATCACATTTAATGGTGTTCCAATC
AGTGATGTTGATCTAACAACGTTACGACAATATATCGAGTATGTGCCACAAGATCCGTTTATTTTTTCTGGCTCAGTCAT
TGAAAACTTAACGTTGGGTAGCCGTTCGAATATCACTGAAGCCGATATTGAAGCTGCCTGTTCAGTGGCGGAAATTGCCG
GAGATATTTCGAATTTGCCGCAGATATGGCAGACCAAACTTTCTGAAAGCGGCAGTATTTTATCGGGTGGACAAAAGCAG
CGCCTAGCAATTGCCCGCGCGTTATTATCACCGGCAAAAGTGTTGATTTTTGATGAATCGACCAGCAGTTTAGATACGAT
CACCGAGCGAAAAATTGTTGATCGGTTGTTAGCGATGACTGATCGAACCATTATTTTTGTGGCTCATCGGCTCACTATTG
CTGCTAAAACGGAACAGATTGTGGTCATGGACCATGGTGCGATTGTTGAACAAGGAAATCATACTGAGTTATTGGCCAAA
CAAGGCTATTATGCTCGGTTGGTAAGTGAGTGA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (180-448)

• ABC transporter (ABC_tran) (510-662)

• Peptidase C39 family (Peptidase_C39) (16-152)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus mitis NCTC 12261	58.914	98.356	0.579
comA	Streptococcus pneumoniae Rx1	58.357	98.356	0.574
comA	Streptococcus pneumoniae D39	58.357	98.356	0.574
comA	Streptococcus pneumoniae R6	58.357	98.356	0.574
comA	Streptococcus mitis SK321	58.217	98.356	0.573
comA	Streptococcus pneumoniae TIGR4	57.939	98.356	0.57
comA	Streptococcus gordonii str. Challis substr. CH1	57.103	98.356	0.562
comA/nlmT	Streptococcus mutans UA159	54.986	98.904	0.544