Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KKZ13_RS12195 Genome accession   NZ_CP075737
Coordinates   2548622..2549746 (-) Length   374 a.a.
NCBI ID   WP_000228555.1    Uniprot ID   -
Organism   Escherichia coli strain CPF6     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 2543622..2554746
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KKZ13_RS12165 (KKZ13_12135) yrdA 2545422..2545976 (+) 555 WP_001286216.1 gamma carbonic anhydrase family protein -
  KKZ13_RS12170 (KKZ13_12140) yrdB 2545952..2546209 (-) 258 WP_001070563.1 DUF1488 domain-containing protein -
  KKZ13_RS12175 (KKZ13_12145) aroE 2546206..2547024 (-) 819 WP_000451218.1 shikimate dehydrogenase -
  KKZ13_RS12180 (KKZ13_12150) tsaC 2547029..2547601 (-) 573 WP_001297709.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  KKZ13_RS12185 (KKZ13_12155) yrdD 2547606..2548148 (-) 543 WP_001129723.1 type I DNA topoisomerase -
  KKZ13_RS12190 (KKZ13_12160) smg 2548177..2548650 (-) 474 WP_000460670.1 DUF494 family protein Smg -
  KKZ13_RS12195 (KKZ13_12165) dprA 2548622..2549746 (-) 1125 WP_000228555.1 DNA-protecting protein DprA Machinery gene
  KKZ13_RS12200 (KKZ13_12170) def 2549876..2550385 (+) 510 WP_000114985.1 peptide deformylase -
  KKZ13_RS12205 (KKZ13_12175) fmt 2550400..2551347 (+) 948 WP_000004438.1 methionyl-tRNA formyltransferase -
  KKZ13_RS12210 (KKZ13_12180) rsmB 2551393..2552682 (+) 1290 WP_000744778.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KKZ13_RS12215 (KKZ13_12185) trkA 2552704..2554080 (+) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  KKZ13_RS12220 (KKZ13_12190) mscL 2554210..2554620 (+) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40994.94 Da        Isoelectric Point: 6.2655

>NTDB_id=500077 KKZ13_RS12195 WP_000228555.1 2548622..2549746(-) (dprA) [Escherichia coli strain CPF6]
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=500077 KKZ13_RS12195 WP_000228555.1 2548622..2549746(-) (dprA) [Escherichia coli strain CPF6]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGTATTGCTGTATTAGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCTCTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTTTAAGTAAAGGCGTACTGGTGGTGGAAGCTGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCTGGTCCATTAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTAACTCAATTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.238

98.663

0.476
  dprA Vibrio cholerae O1 biovar El Tor strain E7946

48.71

82.888

0.404
  dprA Vibrio cholerae strain A1552

48.71

82.888

0.404
  dprA Glaesserella parasuis strain SC1401

44.807

90.107

0.404
  dprA Haemophilus influenzae Rd KW20

43.62

90.107

0.393
  dprA Legionella pneumophila strain ERS1305867

43.939

88.235

0.388