NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	JFY30_RS15725	Genome accession	NZ_CP075665
Coordinates	3136627..3137751 (-)	Length	374 a.a.
NCBI ID	WP_000228519.1	Uniprot ID	-
Organism	Escherichia coli strain STEC2018-553
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 3131627..3142751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JFY30_RS15695 (JFY30_15695)	yrdA	3133427..3133981 (+)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
JFY30_RS15700 (JFY30_15700)	yrdB	3133957..3134214 (-)	258	WP_001070563.1	DUF1488 domain-containing protein	-
JFY30_RS15705 (JFY30_15705)	aroE	3134211..3135029 (-)	819	WP_000451238.1	shikimate dehydrogenase	-
JFY30_RS15710 (JFY30_15710)	tsaC	3135034..3135606 (-)	573	WP_096849349.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
JFY30_RS15715 (JFY30_15715)	yrdD	3135611..3136153 (-)	543	WP_001129723.1	type I DNA topoisomerase	-
JFY30_RS15720 (JFY30_15720)	smg	3136182..3136655 (-)	474	WP_000460670.1	DUF494 family protein Smg	-
JFY30_RS15725 (JFY30_15725)	dprA	3136627..3137751 (-)	1125	WP_000228519.1	DNA-protecting protein DprA	Machinery gene
JFY30_RS15730 (JFY30_15730)	def	3137881..3138390 (+)	510	WP_000114984.1	peptide deformylase	-
JFY30_RS15735 (JFY30_15735)	fmt	3138405..3139352 (+)	948	WP_000004432.1	methionyl-tRNA formyltransferase	-
JFY30_RS15740 (JFY30_15740)	rsmB	3139398..3140687 (+)	1290	WP_000744779.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
JFY30_RS15745 (JFY30_15745)	trkA	3140709..3142085 (+)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
JFY30_RS15750 (JFY30_15750)	mscL	3142215..3142625 (+)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 41006.95 Da Isoelectric Point: 6.3839

                                >NTDB_id=499592 JFY30_RS15725 WP_000228519.1 3136627..3137751(-) (dprA) [Escherichia coli strain STEC2018-553]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLQATTDYPGALFVEGELHALHSFQLAIVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=499592 JFY30_RS15725 WP_000228519.1 3136627..3137751(-) (dprA) [Escherichia coli strain STEC2018-553]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACTGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCAGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCATAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACAAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTTTGCT

TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTAGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Haemophilus influenzae Rd KW20	45.401	90.107	0.409
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.355	82.888	0.409
dprA	Vibrio cholerae strain A1552	49.355	82.888	0.409
dprA	Glaesserella parasuis strain SC1401	45.104	90.107	0.406
dprA	Legionella pneumophila strain ERS1305867	44.545	88.235	0.393

Detailed information NTG0499592