Detailed information
Bioinformatically predicted
Overview
| Name | comR | Type | Regulator |
| Locus tag | SSUA7_RS00345 | Genome accession | NC_017622 |
| Coordinates | 55731..56630 (+) | Length | 299 a.a. |
| NCBI ID | WP_012774888.1 | Uniprot ID | A0A116VRL0 |
| Organism | Streptococcus suis A7 | ||
| Function | activate transcription of comX (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 13656..54847 | 55731..56630 | flank | 884 |
Gene organization within MGE regions
Location: 13656..56630
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SSUA7_RS00075 (SSUA7_0015) | ftsH | 13656..15629 (+) | 1974 | WP_011921638.1 | ATP-dependent zinc metalloprotease FtsH | - |
| SSUA7_RS00080 (SSUA7_0016) | comX/sigX | 15967..16437 (+) | 471 | WP_011921639.1 | sigma-70 family RNA polymerase sigma factor | Regulator |
| SSUA7_RS00200 (SSUA7_0019) | mreC | 23880..24716 (+) | 837 | WP_011921640.1 | rod shape-determining protein MreC | - |
| SSUA7_RS00205 (SSUA7_0020) | mreD | 24706..25221 (+) | 516 | WP_002935339.1 | rod shape-determining protein MreD | - |
| SSUA7_RS00210 (SSUA7_0021) | pcsB | 25306..26562 (+) | 1257 | WP_014638880.1 | peptidoglycan hydrolase PcsB | - |
| SSUA7_RS00215 (SSUA7_0022) | - | 26665..27633 (+) | 969 | WP_002935337.1 | ribose-phosphate diphosphokinase | - |
| SSUA7_RS00220 (SSUA7_0023) | - | 27720..28898 (+) | 1179 | WP_011922532.1 | pyridoxal phosphate-dependent aminotransferase | - |
| SSUA7_RS00225 (SSUA7_0024) | recO | 28885..29667 (+) | 783 | WP_002935335.1 | DNA repair protein RecO | - |
| SSUA7_RS00230 (SSUA7_0025) | plsX | 29664..30671 (+) | 1008 | WP_011921644.1 | phosphate acyltransferase PlsX | - |
| SSUA7_RS00235 (SSUA7_0026) | - | 30664..30912 (+) | 249 | WP_011921645.1 | phosphopantetheine-binding protein | - |
| SSUA7_RS00240 (SSUA7_0027) | purC | 31030..31737 (+) | 708 | WP_011921646.1 | phosphoribosylaminoimidazolesuccinocarboxamide synthase | - |
| SSUA7_RS00245 (SSUA7_0028) | - | 31750..35469 (+) | 3720 | WP_012774881.1 | phosphoribosylformylglycinamidine synthase | - |
| SSUA7_RS00250 (SSUA7_0029) | purF | 35472..36926 (+) | 1455 | WP_011921648.1 | amidophosphoribosyltransferase | - |
| SSUA7_RS00255 (SSUA7_0030) | purM | 36982..38004 (+) | 1023 | Protein_27 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| SSUA7_RS00260 (SSUA7_0031) | purN | 38001..38552 (+) | 552 | WP_011922533.1 | phosphoribosylglycinamide formyltransferase | - |
| SSUA7_RS00265 (SSUA7_0032) | purH | 38562..40109 (+) | 1548 | WP_011921652.1 | bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase | - |
| SSUA7_RS00270 (SSUA7_0033) | purD | 40235..41497 (+) | 1263 | WP_011921653.1 | phosphoribosylamine--glycine ligase | - |
| SSUA7_RS00275 (SSUA7_0034) | purE | 41523..42011 (+) | 489 | WP_011921654.1 | 5-(carboxyamino)imidazole ribonucleotide mutase | - |
| SSUA7_RS00280 (SSUA7_0035) | purK | 41998..43077 (+) | 1080 | WP_012774883.1 | 5-(carboxyamino)imidazole ribonucleotide synthase | - |
| SSUA7_RS00285 (SSUA7_0036) | - | 43121..43882 (+) | 762 | WP_011921656.1 | hypothetical protein | - |
| SSUA7_RS00290 (SSUA7_0037) | - | 43955..45181 (+) | 1227 | WP_011922536.1 | hypothetical protein | - |
| SSUA7_RS00295 (SSUA7_0038) | purB | 45183..46475 (+) | 1293 | WP_011921659.1 | adenylosuccinate lyase | - |
| SSUA7_RS00300 (SSUA7_0040) | - | 47412..48140 (+) | 729 | WP_012774884.1 | hypothetical protein | - |
| SSUA7_RS00305 (SSUA7_0041) | - | 48150..48728 (+) | 579 | WP_011921662.1 | CPBP family intramembrane glutamic endopeptidase | - |
| SSUA7_RS00310 (SSUA7_0042) | - | 48743..49171 (+) | 429 | WP_014636188.1 | Msa family membrane protein | - |
| SSUA7_RS00315 (SSUA7_0043) | - | 49164..50036 (+) | 873 | WP_011921665.1 | ABC transporter ATP-binding protein | - |
| SSUA7_RS00320 (SSUA7_0044) | - | 50042..50815 (+) | 774 | WP_012775420.1 | membrane protein | - |
| SSUA7_RS00325 (SSUA7_0045) | - | 50818..52530 (+) | 1713 | WP_012774887.1 | ABC transporter ATP-binding protein | - |
| SSUA7_RS10535 (SSUA7_0046) | - | 52632..52805 (+) | 174 | WP_011921669.1 | hypothetical protein | - |
| SSUA7_RS00330 (SSUA7_0047) | ruvB | 53100..54101 (+) | 1002 | WP_004195448.1 | Holliday junction branch migration DNA helicase RuvB | - |
| SSUA7_RS00335 (SSUA7_0048) | - | 54101..54847 (+) | 747 | WP_011921670.1 | GNAT family N-acetyltransferase | - |
| SSUA7_RS00340 (SSUA7_0049) | - | 54849..55484 (+) | 636 | WP_011921671.1 | HAD-IA family hydrolase | - |
| SSUA7_RS00345 (SSUA7_0050) | comR | 55731..56630 (+) | 900 | WP_012774888.1 | helix-turn-helix domain-containing protein | Regulator |
Sequence
Protein
Download Length: 299 a.a. Molecular weight: 35405.30 Da Isoelectric Point: 4.6492
>NTDB_id=49811 SSUA7_RS00345 WP_012774888.1 55731..56630(+) (comR) [Streptococcus suis A7]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ
Nucleotide
Download Length: 900 bp
>NTDB_id=49811 SSUA7_RS00345 WP_012774888.1 55731..56630(+) (comR) [Streptococcus suis A7]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGTG
TAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTTTACGAGACACGCTATTATCTTGTG
TAAATATATTAGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
AGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAGAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comR | Streptococcus suis P1/7 |
100 |
100 |
1 |
| comR | Streptococcus suis 05ZYH33 |
100 |
100 |
1 |
| comR | Streptococcus suis D9 |
62.126 |
100 |
0.625 |
| comR | Streptococcus mutans UA159 |
43.813 |
100 |
0.438 |
| comR | Streptococcus pyogenes MGAS315 |
37.374 |
99.331 |
0.371 |