Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SSUD12_RS09165 Genome accession   NC_017621
Coordinates   1837281..1838003 (-) Length   240 a.a.
NCBI ID   WP_014638627.1    Uniprot ID   -
Organism   Streptococcus suis D12     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1832281..1843003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS09145 (SSUD12_1848) - 1832437..1833660 (-) 1224 WP_014638624.1 cysteine desulfurase -
  SSUD12_RS09150 (SSUD12_1849) sufD 1833664..1834926 (-) 1263 WP_014638625.1 Fe-S cluster assembly protein SufD -
  SSUD12_RS09155 (SSUD12_1850) sufC 1834943..1835716 (-) 774 WP_002938165.1 Fe-S cluster assembly ATPase SufC -
  SSUD12_RS09160 (SSUD12_1851) - 1836112..1837284 (-) 1173 WP_014638626.1 glycosyltransferase family 4 protein -
  SSUD12_RS09165 (SSUD12_1852) mecA 1837281..1838003 (-) 723 WP_014638627.1 adaptor protein MecA Regulator
  SSUD12_RS09170 (SSUD12_1853) - 1838131..1838967 (-) 837 WP_014638628.1 undecaprenyl-diphosphate phosphatase -
  SSUD12_RS09175 (SSUD12_1854) - 1839093..1840658 (+) 1566 WP_014638629.1 ABC transporter substrate-binding protein/permease -
  SSUD12_RS09180 (SSUD12_1855) - 1840651..1841394 (+) 744 WP_012775335.1 amino acid ABC transporter ATP-binding protein -
  SSUD12_RS09185 (SSUD12_1856) - 1841517..1841726 (-) 210 WP_009910800.1 hypothetical protein -
  SSUD12_RS09190 (SSUD12_1857) - 1841812..1842714 (-) 903 WP_002942264.1 SPFH domain-containing protein -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 27929.50 Da        Isoelectric Point: 4.0691

>NTDB_id=49803 SSUD12_RS09165 WP_014638627.1 1837281..1838003(-) (mecA) [Streptococcus suis D12]
MKVKQISDSTLKITIKLDDLEERGMELSDFLIPQEKTEEFFYTVLDELDLPMTFRESGMLSFRVTPKPDRVDIFVTKSDL
DQSLNFDEFTDLSELGDVASMTPDEFFKSLEQTVREKSAPDATAVRHLEEVEQEEEADEEEQERYIYYILEFPTIEALFT
FVGTVDYPVEESELYKMDGHYYLTVLINVENRSKQYPGYILSRMLEFTNDTKLTRPALQEHGTLMLPLAAIEELRKVPTV

Nucleotide


Download         Length: 723 bp        

>NTDB_id=49803 SSUD12_RS09165 WP_014638627.1 1837281..1838003(-) (mecA) [Streptococcus suis D12]
ATGAAAGTAAAGCAAATTAGTGATTCAACCTTGAAAATCACTATAAAATTAGATGATTTGGAAGAGAGAGGAATGGAACT
TTCGGACTTTCTCATTCCGCAAGAAAAGACAGAGGAGTTCTTCTATACTGTTTTGGATGAATTGGATTTACCAATGACTT
TCCGAGAAAGCGGTATGCTGAGTTTTCGTGTGACTCCGAAGCCAGATCGGGTGGACATCTTTGTTACCAAATCTGATTTG
GATCAGAGCTTGAATTTCGATGAATTTACAGATTTGTCGGAACTTGGTGATGTCGCAAGTATGACTCCAGATGAGTTTTT
CAAGAGTTTGGAACAAACCGTTCGTGAGAAAAGTGCACCGGATGCAACAGCCGTTCGTCATTTGGAAGAGGTAGAGCAAG
AGGAAGAAGCAGATGAAGAGGAGCAGGAGCGCTATATTTACTATATTTTGGAATTTCCAACGATAGAGGCTCTGTTTACT
TTTGTTGGTACGGTTGATTATCCAGTAGAAGAATCGGAATTATATAAAATGGATGGTCACTACTATTTGACCGTTCTTAT
CAATGTAGAAAATCGTTCCAAGCAGTATCCAGGCTACATTCTCTCACGGATGTTGGAATTTACCAATGATACTAAGTTGA
CCAGACCTGCTTTACAAGAACACGGAACTTTGATGCTTCCGCTTGCGGCAATCGAGGAGCTTAGGAAGGTTCCGACAGTA
TGA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-234)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

51.23

100

0.521
  mecA Streptococcus pneumoniae D39

51.23

100

0.521
  mecA Streptococcus pneumoniae R6

51.23

100

0.521
  mecA Streptococcus pneumoniae TIGR4

51.23

100

0.521
  mecA Streptococcus mutans UA159

50

100

0.508
  mecA Streptococcus thermophilus LMD-9

47.5

100

0.475
  mecA Streptococcus thermophilus LMG 18311

47.083

100

0.471

Multiple sequence alignment