NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	IGI19_RS02750	Genome accession	NZ_CP075462
Coordinates	468489..469613 (+)	Length	374 a.a.
NCBI ID	WP_064670502.1	Uniprot ID	-
Organism	Escherichia coli strain NT1F10
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 463489..474613

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IGI19_RS02725	mscL	463615..464025 (-)	411	WP_000022442.1	large-conductance mechanosensitive channel protein MscL	-
IGI19_RS02730	trkA	464155..465531 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
IGI19_RS02735	rsmB	465553..466842 (-)	1290	WP_000744778.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
IGI19_RS02740	fmt	466888..467835 (-)	948	WP_000004473.1	methionyl-tRNA formyltransferase	-
IGI19_RS02745	def	467850..468359 (-)	510	WP_000114984.1	peptide deformylase	-
IGI19_RS02750	dprA	468489..469613 (+)	1125	WP_064670502.1	DNA-protecting protein DprA	Machinery gene
IGI19_RS02755	smg	469585..470058 (+)	474	WP_000460680.1	DUF494 family protein Smg	-
IGI19_RS02760	yrdD	470087..470629 (+)	543	WP_001129722.1	type I DNA topoisomerase	-
IGI19_RS02765	tsaC	470634..471206 (+)	573	WP_001301412.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
IGI19_RS02770	aroE	471211..472029 (+)	819	WP_064670501.1	shikimate dehydrogenase	-
IGI19_RS02775	yrdB	472026..472283 (+)	258	WP_001070563.1	DUF1488 domain-containing protein	-
IGI19_RS02780	yrdA	472259..472813 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-
IGI19_RS02785	-	472842..473066 (+)	225	WP_154205229.1	hypothetical protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40970.96 Da Isoelectric Point: 6.3122

                                >NTDB_id=497958 IGI19_RS02750 WP_064670502.1 468489..469613(+) (dprA) [Escherichia coli strain NT1F10]

MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYLGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=497958 IGI19_RS02750 WP_064670502.1 468489..469613(+) (dprA) [Escherichia coli strain NT1F10]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG

GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCTCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT

TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

DprA winged helix domain (WHD_DprA)

(312-357)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	47.967	98.663	0.473
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	49.032	82.888	0.406
dprA	Vibrio cholerae strain A1552	49.032	82.888	0.406
dprA	Haemophilus influenzae Rd KW20	44.807	90.107	0.404
dprA	Glaesserella parasuis strain SC1401	44.51	90.107	0.401
dprA	Legionella pneumophila strain ERS1305867	43.939	88.235	0.388

Detailed information NTG0497958