Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SSUD9_RS03145 Genome accession   NC_017620
Coordinates   618033..618737 (+) Length   234 a.a.
NCBI ID   WP_002935840.1    Uniprot ID   A0A0M9FML3
Organism   Streptococcus suis D9     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 613033..623737
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD9_RS03125 (SSUD9_0624) - 614858..615500 (-) 643 Protein_565 amino acid ABC transporter permease -
  SSUD9_RS03130 (SSUD9_0626) - 615515..616213 (-) 699 WP_002935835.1 amino acid ABC transporter permease -
  SSUD9_RS03135 (SSUD9_0627) - 616228..617067 (-) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  SSUD9_RS03140 (SSUD9_0628) - 617078..617839 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  SSUD9_RS03145 (SSUD9_0629) micA 618033..618737 (+) 705 WP_002935840.1 response regulator YycF Regulator
  SSUD9_RS03150 (SSUD9_0630) micB 618730..620079 (+) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SSUD9_RS03155 (SSUD9_0631) vicX 620086..620889 (+) 804 WP_002935843.1 MBL fold metallo-hydrolase Regulator
  SSUD9_RS03160 (SSUD9_0633) - 621513..622715 (-) 1203 WP_014636845.1 IS110 family transposase -
  SSUD9_RS03165 (SSUD9_0634) - 622954..623409 (+) 456 WP_002935846.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26751.75 Da        Isoelectric Point: 4.8957

>NTDB_id=49731 SSUD9_RS03145 WP_002935840.1 618033..618737(+) (micA) [Streptococcus suis D9]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDAPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=49731 SSUD9_RS03145 WP_002935840.1 618033..618737(+) (micA) [Streptococcus suis D9]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTTGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTACAGGCGCGTGTTAAGGCTCTTCTTCGCCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTTGCTAAGAAGCATGGTAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATGCAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0M9FML3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.545

99.573

0.812
  vicR Streptococcus mutans UA159

80

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376

Multiple sequence alignment