Detailed information NTG0049698

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSU12_RS08090
• Genome accession: NC_017619
• Coordinates: 1607869..1608918 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis SS12
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1602869..1613918

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU12_RS08070 (SSU12_1621)	nadE	1603275..1604099 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSU12_RS08075 (SSU12_1622)	-	1605395..1605922 (-)	528	WP_012027591.1	VanZ family protein	-
SSU12_RS08080 (SSU12_1623)	rlmN	1605919..1607031 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSU12_RS08085 (SSU12_1624)	-	1607040..1607681 (-)	642	WP_012027595.1	YutD-like domain-containing protein	-
SSU12_RS08090 (SSU12_1625)	sepM	1607869..1608918 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSU12_RS08095 (SSU12_1626)	coaD	1608905..1609393 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSU12_RS08100 (SSU12_1627)	rsmD	1609383..1609922 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSU12_RS08105 (SSU12_1628)	-	1610230..1610952 (-)	723	WP_012027598.1	lipoprotein	-
SSU12_RS08110 (SSU12_1629)	-	1611009..1611395 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSU12_RS08115 (SSU12_1630)	-	1611395..1611613 (-)	219	WP_004194736.1	YqgQ family protein	-
SSU12_RS08120 (SSU12_1631)	-	1611921..1612523 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSU12_RS08125 (SSU12_1632)	-	1612520..1613614 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=49698 SSU12_RS08090 WP_012775295.1 1607869..1608918(-) (sepM) [Streptococcus suis SS12]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=49698 SSU12_RS08090 WP_012775295.1 1607869..1608918(-) (sepM) [Streptococcus suis SS12]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605