NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	KIM10_RS02355	Genome accession	NZ_CP074909
Coordinates	491134..492258 (+)	Length	374 a.a.
NCBI ID	WP_000228529.1	Uniprot ID	-
Organism	Escherichia coli strain 08_3449
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 486134..497258

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KIM10_RS02330 (KIM10_02330)	mscL	486260..486670 (-)	411	WP_000022439.1	large-conductance mechanosensitive channel protein MscL	-
KIM10_RS02335 (KIM10_02335)	trkA	486800..488176 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
KIM10_RS02340 (KIM10_02340)	rsmB	488198..489487 (-)	1290	WP_032345254.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
KIM10_RS02345 (KIM10_02345)	fmt	489533..490480 (-)	948	WP_032345255.1	methionyl-tRNA formyltransferase	-
KIM10_RS02350 (KIM10_02350)	def	490495..491004 (-)	510	WP_000114986.1	peptide deformylase	-
KIM10_RS02355 (KIM10_02355)	dprA	491134..492258 (+)	1125	WP_000228529.1	DNA-protecting protein DprA	Machinery gene
KIM10_RS02360 (KIM10_02360)	smg	492230..492703 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
KIM10_RS02365 (KIM10_02365)	yrdD	492732..493274 (+)	543	WP_001129719.1	type I DNA topoisomerase	-
KIM10_RS02370 (KIM10_02370)	tsaC	493279..493851 (+)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
KIM10_RS02375 (KIM10_02375)	aroE	493856..494674 (+)	819	WP_000451211.1	shikimate dehydrogenase	-
KIM10_RS02380 (KIM10_02380)	yrdB	494671..494928 (+)	258	WP_001070563.1	DUF1488 domain-containing protein	-
KIM10_RS02385 (KIM10_02385)	yrdA	494904..495458 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40926.86 Da Isoelectric Point: 6.3122

                                >NTDB_id=495108 KIM10_RS02355 WP_000228529.1 491134..492258(+) (dprA) [Escherichia coli strain 08_3449]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=495108 KIM10_RS02355 WP_000228529.1 491134..492258(+) (dprA) [Escherichia coli strain 08_3449]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTCTGCT

TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	44.865	98.93	0.444
dprA	Vibrio cholerae strain A1552	44.865	98.93	0.444
dprA	Haemophilus influenzae Rd KW20	45.401	90.107	0.409
dprA	Glaesserella parasuis strain SC1401	44.838	90.642	0.406
dprA	Legionella pneumophila strain ERS1305867	44.545	88.235	0.393

Detailed information NTG0495108