Detailed information NTG0049482

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: SALIVA_RS07930
• Genome accession: NC_017595
• Coordinates: 1764821..1767061 (-)
• Length: 746 a.a.
• NCBI ID: WP_014634897.1
• Uniprot ID: -
• Organism: Streptococcus salivarius JIM8777
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1759821..1772061

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SALIVA_RS07910 (SALIVA_1613)	-	1760685..1761545 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
SALIVA_RS07915 (SALIVA_1614)	spxR	1761589..1762869 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
SALIVA_RS07920 (SALIVA_1615)	-	1762862..1763407 (-)	546	WP_014634895.1	GNAT family N-acetyltransferase	-
SALIVA_RS07925 (SALIVA_1616)	-	1763473..1764735 (-)	1263	WP_014634896.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SALIVA_RS07930 (SALIVA_1617)	comEC/celB	1764821..1767061 (-)	2241	WP_014634897.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SALIVA_RS07935 (SALIVA_1618)	comEA	1767051..1767746 (-)	696	WP_014634898.1	helix-hairpin-helix domain-containing protein	Machinery gene
SALIVA_RS07940 (SALIVA_1619)	-	1767854..1768609 (-)	756	WP_002948862.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
SALIVA_RS07945 (SALIVA_1620)	-	1768739..1769686 (+)	948	WP_014634899.1	polysaccharide deacetylase family protein	-
SALIVA_RS07950 (SALIVA_1621)	-	1769736..1770500 (+)	765	WP_014634900.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SALIVA_RS07955 (SALIVA_1622)	-	1770504..1770773 (+)	270	WP_014634901.1	GIY-YIG nuclease family protein	-
SALIVA_RS07960 (SALIVA_1623)	-	1770983..1771798 (+)	816	WP_014634902.1	SH3 domain-containing protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84621.47 Da
• Isoelectric Point: 9.8074

>NTDB_id=49482 SALIVA_RS07930 WP_014634897.1 1764821..1767061(-) (comEC/celB) [Streptococcus salivarius JIM8777]
MWLKKAPISLFSLSLLIAALYFTIFITNVYAIGTFVFLMVCFLKHHWKNKTALKLVGLVGSFFLVYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKSEKEQHFFKTTSQTLALKGKIKLSPVTGQRNFQGFNYQSY
LASQGIYRMAQIERLDHVVSQKNTSPLAFFHQLRMRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLFIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLMFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFVLSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVLLFDFWKKPQFRICLLMIFGLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGLKEKWQEASQTSNAEKTLIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVAKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSNLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMASYPTLRASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETIERFKQRH
IKILRTDKDGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=49482 SALIVA_RS07930 WP_014634897.1 1764821..1767061(-) (comEC/celB) [Streptococcus salivarius JIM8777]
ATGTGGCTTAAAAAAGCGCCAATCAGTCTTTTTTCCTTGTCTCTTTTAATAGCTGCCCTTTATTTTACGATTTTTATCAC
TAATGTTTATGCTATTGGGACTTTTGTCTTTCTGATGGTCTGTTTTTTGAAGCATCATTGGAAGAATAAGACAGCCCTAA
AGTTGGTGGGACTTGTAGGTAGTTTCTTTTTGGTCTACTTTTTATTCTTGCATCATAGAGCTAGCATACAAGATAAACAA
GCCCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCCGCTATCGGTAA
GGCAAAGGGACAAACCTATCAGGTCTTTTACCGACTCAAATCTGAGAAGGAGCAGCATTTTTTTAAGACTACTAGCCAAA
CATTGGCATTAAAAGGGAAAATAAAGTTATCCCCAGTAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAATCTTAT
CTAGCCAGTCAAGGTATTTATCGAATGGCTCAGATTGAGCGCTTGGATCATGTGGTGTCTCAAAAAAACACATCTCCCCT
AGCTTTTTTCCATCAATTGAGGATGAGGGCTTTGGTTCATATCCAGACGCATTTTCCTAATCCTATGAGACACTATATGA
CAGGTTTGCTTTTTGGGTATTTGGATAAGGAGTTCGATGAGCAGAGTCAGCTTTACACAAGTTTAGGGATTATTCATCTA
TTCGCACTTTCGGGGATGCAAGTGGGCTTTTTTCTGGGATGGTTTCGTTACGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTTATTATCTTGCTGCCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACGGCTTCAGTTCTACGTTCCC
TGATTCAAAGTTTGTTGGCGGAGTTTGGTATTAAAAAACTGGACAATATGGGAATAACCTTGCTTCTAATGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTTTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACAGCGATGTTTTCGATAGTCTTTGATAGCTTTCTCTTACCTGTCTTGACG
GTCTTCTTTGTCCTTTCAGGGTTGGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTCTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTCTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGGATTTGCCTTTTGATGATTTTTGGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTGATTGATGTGGGTGGCAAGGTGACTTTCGGCCTAAAGGAAAAATGGCAAGAGGCTAGTCAGACGAGCAATG
CGGAGAAAACCTTGATTCCCTACCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAAGAAGTAGCCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTAGGACTTTAAAACGCCCAGTTCGTACTCTAAAGGCTGGAGACAACTTACCTATGATGG
GAAGCAATCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCGATAGTTCTTTACGGAAAGCTA
TTAGGAAGCAGTTTTCTGTTTACCGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTGATGGCTAGCTATCCAACTTTAAG
GGCAAGCGTCCTCAAAGCTGGACACCACGGTTCAAAAGGTTCTTCGTCTGAAGCTTTTTTGGACCAGCTGCACCCCTCCC
TTGCACTTGTTTCAGCTGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACAATAGAACGTTTTAAGCAACGCCAC
ATTAAAATTTTACGAACAGATAAAGACGGAGCCATCCGTTTTAAAGGCTGGTTTAAATGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-694)

• Domain of unknown function (DUF4131) (DUF4131) (30-169)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.327	100	0.484
comEC/celB	Streptococcus mitis SK321	48.128	100	0.483
comEC/celB	Streptococcus pneumoniae R6	47.333	100	0.476
comEC/celB	Streptococcus pneumoniae D39	47.333	100	0.476
comEC/celB	Streptococcus pneumoniae Rx1	47.333	100	0.476
comEC/celB	Streptococcus pneumoniae TIGR4	46.996	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.108	99.196	0.428