Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   SALIVA_RS07350 Genome accession   NC_017595
Coordinates   1648209..1650083 (-) Length   624 a.a.
NCBI ID   WP_014634811.1    Uniprot ID   A0AAW6D2Y1
Organism   Streptococcus salivarius JIM8777     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1643209..1655083
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVA_RS07315 (SALIVA_1493) rimM 1643586..1644104 (-) 519 WP_002884411.1 ribosome maturation factor RimM -
  SALIVA_RS07330 (SALIVA_1496) - 1644801..1645445 (-) 645 WP_002884791.1 response regulator transcription factor -
  SALIVA_RS07335 (SALIVA_1497) - 1645435..1646445 (-) 1011 WP_013990239.1 sensor histidine kinase -
  SALIVA_RS07340 (SALIVA_1498) liaF 1646442..1647140 (-) 699 WP_014634809.1 cell wall-active antibiotics response protein LiaF -
  SALIVA_RS07345 (SALIVA_1499) - 1647303..1648061 (-) 759 WP_014634810.1 potassium channel family protein -
  SALIVA_RS07350 (SALIVA_1500) stkP/pknB 1648209..1650083 (-) 1875 WP_014634811.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SALIVA_RS07355 (SALIVA_1501) - 1650083..1650820 (-) 738 WP_037620217.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SALIVA_RS07360 (SALIVA_1502) rsmB 1650864..1652186 (-) 1323 WP_041826748.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SALIVA_RS07365 (SALIVA_1503) fmt 1652176..1653111 (-) 936 WP_014634814.1 methionyl-tRNA formyltransferase -

Sequence

Protein


Download         Length: 624 a.a.        Molecular weight: 67887.56 Da        Isoelectric Point: 6.4576

>NTDB_id=49475 SALIVA_RS07350 WP_014634811.1 1648209..1650083(-) (stkP/pknB) [Streptococcus salivarius JIM8777]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVVGQELSTAQTKIEGAGFKVGEVKEV
EDDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGE
ILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSSTEV
LYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1875 bp        

>NTDB_id=49475 SALIVA_RS07350 WP_014634811.1 1648209..1650083(-) (stkP/pknB) [Streptococcus salivarius JIM8777]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAGAAGTGGCCATTAAGGTGCTTCGTACCAATTACCAAACGGATCAGGTGG
CTGTGGCGCGTTTCCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTACTTTCCGCCATGACACTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACGGCCAAGGTTACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGCCTAACTCAAACCAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAGAGCGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTGACAGGTCATATTCCTTATGATG
GTGATAGTGCAGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCGATTTTGGCAGAGAACCGTAACGTTCCT
CAAGCCTTGGAAAACGTGGTAATTCGAGCAACAGCCAAAAAACTAGAAAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACTAAGACCT
TGCCAAAGGTTGATCCAGTTCCATCAGCAAGCCTTGAGAAAAAGGCTGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCAAGGAAAAAAACGACACCAGCTAAGAAGAAAAAGAAGAAGAATTTCTTCTCAACCTTGCTCAAGGT
TTTCCTAGGACTTGTCTTTATTGGTATCATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTA
ATGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTCAAAGAAGTG
GAAGATGATTCTGTCGATACGGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACTACACGAAAAGAAGGATCAAGCAT
TGATGTCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAACTATAAGGATGCCATTGAGG
ACTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAA
ATCCTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGTGGCAAC
TCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCT
CAAGTAGTAGTATCGAGTATCATGACTATAATACTGGTGCCAAGTTAGACAAGGATAAGGTTCCTAGCAGTACAGAGGTC
CTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAGTTCAAG
CCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAA
CCTCGACAGAGGCTACTCACACAGAGCTACAGTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(441-505)

PASTA domain (PASTA)

(370-432)

PASTA domain (PASTA)

(511-580)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

99.038

100

0.99
  pknB Streptococcus mutans UA159

67.343

86.859

0.585
  stkP Streptococcus pneumoniae D39

52.324

93.109

0.487
  stkP Streptococcus pneumoniae R6

52.324

93.109

0.487
  stkP Streptococcus pneumoniae Rx1

52.151

93.109

0.486
  stkP Streptococcus pneumoniae TIGR4

52.439

91.987

0.482

Multiple sequence alignment