Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   SALIVA_RS06050 Genome accession   NC_017595
Coordinates   1260135..1261550 (-) Length   471 a.a.
NCBI ID   WP_013990466.1    Uniprot ID   -
Organism   Streptococcus salivarius JIM8777     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1255135..1266550
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SALIVA_RS06020 (SALIVA_1233) - 1255773..1256171 (-) 399 WP_014634598.1 cytidine deaminase -
  SALIVA_RS06025 (SALIVA_1234) deoC 1256176..1256820 (-) 645 WP_014634599.1 deoxyribose-phosphate aldolase -
  SALIVA_RS06030 (SALIVA_1235) - 1256854..1258131 (-) 1278 WP_014634600.1 pyrimidine-nucleoside phosphorylase -
  SALIVA_RS06035 (SALIVA_1236) - 1258128..1258718 (-) 591 WP_014633038.1 class I SAM-dependent methyltransferase -
  SALIVA_RS06040 (SALIVA_1237) coaA 1258831..1259751 (+) 921 WP_013990467.1 type I pantothenate kinase -
  SALIVA_RS06045 (SALIVA_1238) rpsT 1259821..1260057 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  SALIVA_RS06050 (SALIVA_1239) ciaH 1260135..1261550 (-) 1416 WP_013990466.1 cell wall metabolism sensor histidine kinase WalK Regulator
  SALIVA_RS06055 (SALIVA_1240) ciaR 1261540..1262214 (-) 675 WP_014634601.1 response regulator transcription factor Regulator
  SALIVA_RS06060 (SALIVA_1241) - 1262414..1264084 (-) 1671 WP_014634602.1 formate--tetrahydrofolate ligase -
  SALIVA_RS06065 (SALIVA_1242) - 1264279..1264962 (+) 684 WP_014634603.1 phosphopantothenate--cysteine ligase -
  SALIVA_RS06070 (SALIVA_1243) coaC 1264955..1265500 (+) 546 WP_014634604.1 phosphopantothenoylcysteine decarboxylase -
  SALIVA_RS06075 (SALIVA_1244) - 1265529..1266101 (+) 573 WP_014634605.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53464.22 Da        Isoelectric Point: 8.7661

>NTDB_id=49471 SALIVA_RS06050 WP_013990466.1 1260135..1261550(-) (ciaH) [Streptococcus salivarius JIM8777]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGATTETSDSSDSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=49471 SALIVA_RS06050 WP_013990466.1 1260135..1261550(-) (ciaH) [Streptococcus salivarius JIM8777]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACGACCATTTACCAGGCTTATGATACTAAAGGGGCGACAACTGAAACATCTGACTCGAGTGA
CTCTAAGAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCAGTTGCGGCAAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AATATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAGAAAGT
AGACAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAAGTTCTTTTCCGCAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATTACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae D39

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae R6

50.431

98.514

0.497
  ciaH Streptococcus pneumoniae TIGR4

50.431

98.514

0.497

Multiple sequence alignment