Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   SSAL_RS09190 Genome accession   NC_017594
Coordinates   1971505..1972254 (-) Length   249 a.a.
NCBI ID   WP_014633671.1    Uniprot ID   A0AAX1YC61
Organism   Streptococcus salivarius 57.I     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1966505..1977254
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS09170 (Ssal_02008) - 1966827..1968059 (-) 1233 WP_014633668.1 cysteine desulfurase -
  SSAL_RS09175 (Ssal_02009) sufD 1968113..1969375 (-) 1263 WP_002886437.1 Fe-S cluster assembly protein SufD -
  SSAL_RS09180 (Ssal_02010) sufC 1969412..1970182 (-) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  SSAL_RS09185 (Ssal_02011) - 1970344..1971501 (-) 1158 WP_014633670.1 MraY family glycosyltransferase -
  SSAL_RS09190 (Ssal_02012) mecA 1971505..1972254 (-) 750 WP_014633671.1 adaptor protein MecA Regulator
  SSAL_RS09195 - 1972461..1972832 (+) 372 WP_045001980.1 DUF3021 family protein -
  SSAL_RS09200 (Ssal_02014) - 1972892..1973746 (-) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  SSAL_RS09205 (Ssal_02015) - 1973952..1975499 (+) 1548 WP_002886433.1 ABC transporter substrate-binding protein/permease -
  SSAL_RS09210 (Ssal_02016) - 1975499..1976239 (+) 741 WP_013989971.1 amino acid ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29146.75 Da        Isoelectric Point: 4.0356

>NTDB_id=49433 SSAL_RS09190 WP_014633671.1 1971505..1972254(-) (mecA) [Streptococcus salivarius 57.I]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSYMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVPEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTVLLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=49433 SSAL_RS09190 WP_014633671.1 1971505..1972254(-) (mecA) [Streptococcus salivarius 57.I]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAGGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCATATATGGATGACTACTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCTCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGCCCGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGACTTTGATCAAGTGGTGACCTTTACACAAGGCTTGAAGGATGTGCCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTATATGACAGTCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTAGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.173

100

0.932
  mecA Streptococcus thermophilus LMG 18311

92.369

100

0.924
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

46.586

100

0.466
  mecA Streptococcus pneumoniae D39

46.586

100

0.466
  mecA Streptococcus pneumoniae R6

46.586

100

0.466
  mecA Streptococcus pneumoniae TIGR4

46.586

100

0.466

Multiple sequence alignment