Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SSAL_RS08540 Genome accession   NC_017594
Coordinates   1842846..1843535 (-) Length   229 a.a.
NCBI ID   WP_002886589.1    Uniprot ID   -
Organism   Streptococcus salivarius 57.I     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1837846..1848535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS08520 (Ssal_01872) dnaI 1838641..1839543 (-) 903 WP_013990064.1 primosomal protein DnaI -
  SSAL_RS08525 (Ssal_01873) - 1839547..1840722 (-) 1176 WP_013990063.1 DnaD domain protein -
  SSAL_RS08530 (Ssal_01874) nrdR 1840719..1841198 (-) 480 WP_014633595.1 transcriptional regulator NrdR -
  SSAL_RS08535 (Ssal_01875) covS 1841320..1842849 (-) 1530 WP_014633596.1 HAMP domain-containing histidine kinase Regulator
  SSAL_RS08540 (Ssal_01876) covR 1842846..1843535 (-) 690 WP_002886589.1 response regulator transcription factor Regulator
  SSAL_RS08545 (Ssal_01877) - 1843691..1844227 (-) 537 WP_013990061.1 YceD family protein -
  SSAL_RS08550 (Ssal_01878) rsmG 1844526..1845239 (+) 714 WP_014633597.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  SSAL_RS08555 (Ssal_01879) - 1845308..1846672 (+) 1365 WP_102787830.1 potassium transporter TrkG -
  SSAL_RS08560 (Ssal_01880) - 1846712..1847383 (+) 672 WP_014633599.1 TrkA family potassium uptake protein -
  SSAL_RS08565 (Ssal_01881) - 1847472..1848302 (-) 831 WP_002886584.1 energy-coupling factor transporter transmembrane component T -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26517.51 Da        Isoelectric Point: 4.6354

>NTDB_id=49424 SSAL_RS08540 WP_002886589.1 1842846..1843535(-) (covR) [Streptococcus salivarius 57.I]
MSKRILIVEDEKNLARFVSLELQHEGYDVVTADNGREGLEMALEKDFDLILLDLMLPEMDGFEVTRRLQQEKDTYIMMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARIRATFRRQDIESAKNAPAKASTYRDLKLDVQNRTVVRGDEAIPLTKRE
FDLLNTLLSNMNQVMTREELLLQVWKYDDAIETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=49424 SSAL_RS08540 WP_002886589.1 1842846..1843535(-) (covR) [Streptococcus salivarius 57.I]
ATGAGCAAACGCATTTTGATTGTTGAAGATGAGAAAAACCTTGCTCGTTTTGTCTCTCTTGAACTTCAACACGAAGGATA
CGACGTTGTGACAGCAGACAACGGACGCGAAGGACTTGAAATGGCACTCGAGAAAGATTTCGATCTTATTCTCTTGGACC
TTATGTTGCCTGAGATGGACGGTTTTGAAGTAACACGTCGTCTCCAACAAGAAAAAGATACTTATATTATGATGATGACA
GCTCGCGATTCAATCATGGACATTGTTGCTGGTTTGGACCGCGGTGCTGATGACTATATTGTAAAACCATTTGCGATTGA
AGAATTGTTGGCACGTATCCGTGCAACCTTCCGTCGCCAAGATATCGAATCTGCTAAGAATGCACCAGCAAAAGCATCAA
CTTATCGTGATTTGAAATTGGATGTTCAAAACCGTACAGTTGTTCGTGGTGATGAAGCAATTCCATTGACAAAACGTGAG
TTTGATTTGTTGAACACACTTTTGAGCAATATGAACCAAGTGATGACCCGTGAGGAACTCTTGCTTCAAGTTTGGAAATA
TGATGACGCAATCGAAACAAACGTTGTAGATGTTTATATTCGTTACTTGCGTGGAAAAATCGACGTTCCAGGTAAGGAAT
CATATATTCAAACAGTACGAGGAATGGGTTACGTTATCCGTGAAAAATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

99.563

100

0.996
  covR Lactococcus lactis subsp. lactis strain DGCC12653

68.421

99.563

0.681
  vicR Streptococcus mutans UA159

46.352

100

0.472
  micA Streptococcus pneumoniae Cp1015

44.156

100

0.445

Multiple sequence alignment