Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   SSAL_RS08535 Genome accession   NC_017594
Coordinates   1841320..1842849 (-) Length   509 a.a.
NCBI ID   WP_014633596.1    Uniprot ID   -
Organism   Streptococcus salivarius 57.I     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1836320..1847849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS08510 (Ssal_01870) - 1836533..1837162 (-) 630 WP_014633594.1 hypothetical protein -
  SSAL_RS08515 (Ssal_01871) der 1837226..1838536 (-) 1311 WP_002886596.1 ribosome biogenesis GTPase Der -
  SSAL_RS08520 (Ssal_01872) dnaI 1838641..1839543 (-) 903 WP_013990064.1 primosomal protein DnaI -
  SSAL_RS08525 (Ssal_01873) - 1839547..1840722 (-) 1176 WP_013990063.1 DnaD domain protein -
  SSAL_RS08530 (Ssal_01874) nrdR 1840719..1841198 (-) 480 WP_014633595.1 transcriptional regulator NrdR -
  SSAL_RS08535 (Ssal_01875) covS 1841320..1842849 (-) 1530 WP_014633596.1 HAMP domain-containing histidine kinase Regulator
  SSAL_RS08540 (Ssal_01876) covR 1842846..1843535 (-) 690 WP_002886589.1 response regulator transcription factor Regulator
  SSAL_RS08545 (Ssal_01877) - 1843691..1844227 (-) 537 WP_013990061.1 YceD family protein -
  SSAL_RS08550 (Ssal_01878) rsmG 1844526..1845239 (+) 714 WP_014633597.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  SSAL_RS08555 (Ssal_01879) - 1845308..1846672 (+) 1365 WP_102787830.1 potassium transporter TrkG -
  SSAL_RS08560 (Ssal_01880) - 1846712..1847383 (+) 672 WP_014633599.1 TrkA family potassium uptake protein -

Sequence

Protein


Download         Length: 509 a.a.        Molecular weight: 58037.45 Da        Isoelectric Point: 5.3910

>NTDB_id=49423 SSAL_RS08535 WP_014633596.1 1841320..1842849(-) (covS) [Streptococcus salivarius 57.I]
MSKLQDKLFGKVTIRKKLTMTTAVVFFLVLSLFTLVVIFSANTLLLQRERQNVNTTIAKVVTYIEKDWDSDEELSPEPLL
AALYSPKNIYASIINGVLSEKHSLDGQVAISNKLYSNQSVFVYDKKGTFIFTSEENTDSPPGMSEVNKLKSVSYKGKRGF
LLQVPIYGKDKKTIVGYAQIFHDLEFYYALKERLVFLLIFLEVGMTVLVIAATVVVLTSILRPMRQLHETMGVITDSPSD
LELRSKIESHDEIGDLAVNFNRMMDKIQENNQMQMRFLSDVSHELRTPIAVIKGHMDLLQRWGKNDPEILEESLEAASHE
ANRMTIMINDMLDSIRVKGSFENHRNDTCDLNSSIRTVIGNFRVLHEDYQFYLNDFESSERLAQIYSQHFEQAITILIDN
AVKYSPVNKEIQVTIKALENEMLVQVQDNGEGISKEDINHIFERFYRSDKARNRTTTQSGVGIGLSILYQIVEAYRCRID
VSSELGVGTRFDLYIPFADGETTTPQLEL

Nucleotide


Download         Length: 1530 bp        

>NTDB_id=49423 SSAL_RS08535 WP_014633596.1 1841320..1842849(-) (covS) [Streptococcus salivarius 57.I]
ATGAGTAAATTACAAGATAAATTATTTGGTAAAGTAACCATTAGAAAAAAGTTGACCATGACAACTGCTGTGGTCTTCTT
TCTTGTATTGTCGTTGTTCACTCTGGTTGTTATTTTTTCAGCTAATACGCTTCTTTTGCAACGTGAACGTCAAAATGTAA
ACACTACAATCGCAAAAGTTGTTACTTACATCGAAAAGGACTGGGATTCGGATGAAGAATTAAGTCCAGAACCGCTCTTA
GCGGCTCTTTATTCGCCTAAAAATATCTATGCATCAATTATTAATGGCGTACTTTCTGAAAAGCACTCTTTGGATGGTCA
AGTTGCAATTTCTAATAAATTATATTCAAATCAGTCAGTTTTTGTGTATGACAAAAAAGGAACCTTTATCTTTACTTCTG
AGGAGAATACAGACTCACCTCCCGGTATGTCCGAGGTAAACAAACTGAAGTCAGTATCCTATAAAGGGAAGCGTGGTTTC
TTACTACAAGTTCCAATTTACGGTAAGGATAAAAAGACCATCGTTGGCTATGCCCAGATTTTCCATGATTTGGAATTCTA
CTATGCTCTTAAAGAGCGTTTGGTCTTCTTGTTGATTTTCCTAGAAGTGGGGATGACTGTCCTAGTTATCGCAGCAACTG
TAGTTGTCTTGACATCTATTCTTCGTCCGATGAGACAGTTGCACGAAACGATGGGAGTTATTACCGATTCGCCAAGTGAT
TTGGAACTTCGTTCTAAGATTGAAAGTCACGATGAAATTGGTGATTTGGCGGTTAACTTTAACCGCATGATGGATAAAAT
TCAAGAAAATAATCAGATGCAGATGCGTTTCTTGAGTGACGTCAGTCATGAATTACGTACGCCGATTGCAGTTATCAAGG
GGCATATGGACCTCTTGCAACGTTGGGGTAAAAATGACCCTGAGATTCTTGAAGAAAGTCTTGAGGCTGCCAGTCACGAG
GCCAACCGTATGACGATTATGATTAATGATATGTTGGATTCTATCCGTGTCAAAGGATCATTTGAAAATCATAGAAACGA
TACTTGTGATTTGAATTCTTCAATCCGTACGGTTATTGGGAACTTCCGTGTCTTGCATGAAGACTATCAATTTTATCTCA
ATGATTTCGAAAGTTCAGAGCGTCTAGCACAGATTTATAGTCAGCACTTTGAACAGGCTATCACCATTTTGATTGATAAT
GCGGTCAAGTATTCGCCTGTCAATAAGGAAATACAGGTTACTATTAAAGCATTGGAAAATGAAATGTTGGTACAAGTGCA
AGATAACGGTGAGGGGATTTCAAAAGAAGATATCAATCATATTTTTGAACGTTTCTATCGTTCAGATAAGGCGCGTAACC
GTACGACAACTCAATCTGGTGTTGGTATTGGTTTGTCAATCCTTTATCAAATTGTGGAAGCTTATCGCTGCCGTATTGAT
GTTAGTTCTGAACTTGGTGTTGGAACACGTTTCGACCTCTACATTCCATTTGCAGATGGAGAAACGACGACACCTCAACT
TGAGCTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(388-497)

HAMP domain (HAMP)

(217-269)

ArlS sensor domain (ArlS_N)

(43-191)

His Kinase A (phospho-acceptor) domain (HisKA)

(274-333)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Streptococcus salivarius strain HSISS4

98.625

100

0.986

Multiple sequence alignment