Detailed information NTG0494193

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: IM723_RS09735
• Genome accession: NZ_CP063275
• Coordinates: 1876707..1877942 (+)
• Length: 411 a.a.
• NCBI ID: WP_176243297.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain DMST-H2
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1871707..1882942

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IM723_RS09705	-	1872174..1874780 (+)	2607	WP_176243296.1	YfhO family protein	-
IM723_RS09725	-	1875324..1876007 (-)	684	WP_096811735.1	YoaK family protein	-
IM723_RS09730	rlmH	1876023..1876502 (-)	480	WP_002952297.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
IM723_RS09735	htrA	1876707..1877942 (+)	1236	WP_176243297.1	trypsin-like peptidase domain-containing protein	Regulator
IM723_RS09740	spo0J	1878008..1878775 (+)	768	WP_176243298.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42927.21 Da
• Isoelectric Point: 4.6536

>NTDB_id=494193 IM723_RS09735 WP_176243297.1 1876707..1877942(+) (htrA) [Streptococcus thermophilus strain DMST-H2]
MKKFNWKKIVAPIAMLIIGLLGGLLGAFILLTAAGVSFTNTTDPGVKTAKTVYTNITDTTKAVKKVQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDDLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKLSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=494193 IM723_RS09735 WP_176243297.1 1876707..1877942(+) (htrA) [Streptococcus thermophilus strain DMST-H2]
ATGAAAAAATTTAACTGGAAGAAAATAGTCGCGCCAATTGCAATGCTAATTATTGGCTTACTAGGTGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATCCTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGTACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGATCTACAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAATTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGCCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAATTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAAATCAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATTGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (4-406)

• PDZ domain (PDZ_2) (307-402)

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.29	98.054	0.601
htrA	Streptococcus gordonii str. Challis substr. CH1	57.282	100	0.574
htrA	Streptococcus mitis NCTC 12261	53.79	99.513	0.535
htrA	Streptococcus pneumoniae TIGR4	53.545	99.513	0.533
htrA	Streptococcus pneumoniae D39	53.545	99.513	0.533
htrA	Streptococcus pneumoniae Rx1	53.545	99.513	0.533
htrA	Streptococcus pneumoniae R6	53.545	99.513	0.533