Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   SSAL_RS02935 Genome accession   NC_017594
Coordinates   580202..582082 (+) Length   626 a.a.
NCBI ID   WP_014632829.1    Uniprot ID   -
Organism   Streptococcus salivarius 57.I     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 575202..587082
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSAL_RS02920 (Ssal_00639) fmt 577174..578109 (+) 936 WP_045001578.1 methionyl-tRNA formyltransferase -
  SSAL_RS02925 (Ssal_00641) rsmB 578099..579421 (+) 1323 WP_045002041.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SSAL_RS02930 (Ssal_00642) - 579465..580202 (+) 738 WP_002886859.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SSAL_RS02935 (Ssal_00643) stkP/pknB 580202..582082 (+) 1881 WP_014632829.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SSAL_RS02940 (Ssal_00644) - 582228..582986 (+) 759 WP_002886861.1 potassium channel family protein -
  SSAL_RS02945 (Ssal_00645) liaF 583150..583848 (+) 699 WP_013990238.1 cell wall-active antibiotics response protein LiaF -
  SSAL_RS02950 (Ssal_00646) - 583845..584855 (+) 1011 WP_013990239.1 sensor histidine kinase -
  SSAL_RS02955 (Ssal_00647) - 584845..585489 (+) 645 WP_002884791.1 response regulator transcription factor -
  SSAL_RS02970 (Ssal_00648) rimM 586184..586702 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 68201.86 Da        Isoelectric Point: 7.3639

>NTDB_id=49396 SSAL_RS02935 WP_014632829.1 580202..582082(+) (stkP/pknB) [Streptococcus salivarius 57.I]
MIQVGKLFAGRYRILKAIGRGGMADVYLANDLILDNEKVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEILSAMTLAHQKGIIHRDLKPQNVLLTKDGRAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGRIPYDGDSAVTIALQHFQKPLPSILAENHNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLYPSHSRDAKVVFDDMTDTKTLPKVTPVPSVSSEKKATAKSSESKQAV
SKQPRKNSTLAKNKKKKKRKDFFSTSLKVFLGLVFIGIIIFAYLVFTNPDSTQVPNVVGQELSTAQTKIEGAGFKVGEVK
EVEDDSVDTGKVVKTDPTAGTTRKEGSSIDIYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEE
GEILSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSST
EVLYQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTESTSSSTETPTEATHTDQQ

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=49396 SSAL_RS02935 WP_014632829.1 580202..582082(+) (stkP/pknB) [Streptococcus salivarius 57.I]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAAGCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATCTTGGATAATGAGAAAGTGGCCATTAAGGTGCTTCGTACTAATTATCAAACCGATCAGGTAG
CTGTGGCACGTTTCCAGCGTGAAGCACGTGCCATGGCAGAACTCAGTCATCCCAATATCGTTGCAATCCGAGACATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTACGTGGATGGTTCGGACTTGAAGAAATATATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATTATGGGAGAGATTCTTTCTGCCATGACTCTTGCCCATCAAAAGGGTATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAAGACGGTAGGGCCAAAGTTACAGACTTCGGGATTGCGGTTGCC
TTTGCAGAGACTAGTTTGACTCAAACCAATTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCGCGTGGATC
TAAAGCAACTATCCAAAGTGATATCTATGCTATGGGTATCATGCTCTTTGAAATGTTGACAGGGCGTATTCCATATGATG
GTGATAGTGCAGTTACCATCGCTCTTCAGCATTTCCAAAAACCATTACCATCAATCTTGGCTGAGAATCATAATGTTCCT
CAGGCATTGGAAAATGTGGTTATTCGAGCGACAGCTAAAAAGCTTGAAAATCGTTATAACAGTACTTTGGAAATGAGCCG
AGATTTAGTAACTAGCTTATATCCTAGCCATAGCCGTGATGCGAAGGTAGTCTTTGATGACATGACGGATACTAAGACTT
TGCCTAAGGTTACTCCAGTTCCGTCAGTAAGCTCTGAGAAAAAGGCAACTGCCAAGTCATCAGAGTCAAAACAAGCTGTA
AGTAAGCAACCAAGGAAAAATTCAACACTAGCTAAGAATAAAAAGAAGAAAAAAAGAAAAGACTTTTTCTCGACATCACT
CAAGGTATTCCTGGGGTTGGTCTTTATCGGGATTATCATTTTTGCCTATTTGGTATTTACCAACCCTGATAGTACTCAGG
TGCCTAACGTGGTCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGTGAAGTTAAG
GAAGTGGAAGATGACTCTGTCGATACAGGCAAGGTCGTAAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATC
AAGCATTGATATCTATGTTTCTTCTGGTAGTAAAGGTTTCGCTTTGAAAGACTACAAAGGTAAAAATTATAAGGATGCCA
TTGAGGATTTAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAG
GGAGAAATCCTATCTCAAAGTCCAGGTAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGT
GGCAACTCCTAAGACAGTTACCATGCCTGATGTGACTGGTTTGACGGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGA
GTATCTCAAGTAGTAGCATCGAGTATCATGACTATAATACTGGTGCTAAGTTAGACAAGGATAAGGTTCCTAGCAGTACA
GAGGTCCTTTATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCGGTTGCAACAGCAAG
TTCAAGCCTACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGAAAGCACAAGCTCTAGTA
CTGAAACACCGACAGAGGCTACTCACACAGACCAACAATAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(373-434)

PASTA domain (PASTA)

(443-507)

PASTA domain (PASTA)

(513-582)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

92.982

100

0.931
  pknB Streptococcus mutans UA159

65.809

86.901

0.572
  stkP Streptococcus pneumoniae TIGR4

51.635

92.812

0.479
  stkP Streptococcus pneumoniae D39

51.463

92.812

0.478
  stkP Streptococcus pneumoniae R6

51.463

92.812

0.478
  stkP Streptococcus pneumoniae Rx1

51.291

92.812

0.476

Multiple sequence alignment