NTDB

Overview

Name	dprA	Type	Machinery gene
Locus tag	KIM26_RS02665	Genome accession	NZ_CP074853
Coordinates	548177..549301 (+)	Length	374 a.a.
NCBI ID	WP_000228529.1	Uniprot ID	-
Organism	Escherichia coli strain 7_11_88A
Function	ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 543177..554301

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KIM26_RS02640 (KIM26_02620)	mscL	543303..543713 (-)	411	WP_000022439.1	large-conductance mechanosensitive channel protein MscL	-
KIM26_RS02645 (KIM26_02625)	trkA	543843..545219 (-)	1377	WP_000691382.1	Trk system potassium transporter TrkA	-
KIM26_RS02650 (KIM26_02630)	rsmB	545241..546530 (-)	1290	WP_000744775.1	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	-
KIM26_RS02655 (KIM26_02635)	fmt	546576..547523 (-)	948	WP_000004477.1	methionyl-tRNA formyltransferase	-
KIM26_RS02660 (KIM26_02640)	def	547538..548047 (-)	510	WP_000114986.1	peptide deformylase	-
KIM26_RS02665 (KIM26_02645)	dprA	548177..549301 (+)	1125	WP_000228529.1	DNA-protecting protein DprA	Machinery gene
KIM26_RS02670 (KIM26_02650)	smg	549273..549746 (+)	474	WP_000460672.1	DUF494 family protein Smg	-
KIM26_RS02675 (KIM26_02655)	yrdD	549775..550317 (+)	543	WP_001129719.1	type I DNA topoisomerase	-
KIM26_RS02680 (KIM26_02660)	tsaC	550322..550894 (+)	573	WP_001297709.1	L-threonylcarbamoyladenylate synthase type 1 TsaC	-
KIM26_RS02685 (KIM26_02665)	aroE	550899..551717 (+)	819	WP_000451211.1	shikimate dehydrogenase	-
KIM26_RS02690 (KIM26_02670)	yrdB	551714..551971 (+)	258	WP_001070563.1	DUF1488 domain-containing protein	-
KIM26_RS02695 (KIM26_02675)	yrdA	551947..552501 (-)	555	WP_001286216.1	gamma carbonic anhydrase family protein	-

Sequence

Protein

Download Length: 374 a.a. Molecular weight: 40926.86 Da Isoelectric Point: 6.3122

                                >NTDB_id=493757 KIM26_RS02665 WP_000228529.1 548177..549301(+) (dprA) [Escherichia coli strain 7_11_88A]

MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE

FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN

GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA

LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE

VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

Download Length: 1125 bp

                                >NTDB_id=493757 KIM26_RS02665 WP_000228529.1 548177..549301(+) (dprA) [Escherichia coli strain 7_11_88A]

ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG

GCTGGCAAAACAGTCGCAAATTGATGCGGTTGGATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT

CATTTCCGCGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA

TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC

ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGGTTATTTTGCGAAACTCTGG

CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT

GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGCCATGCCCGACTGGCTGCCAGTCTGCT

TGAACATGGCGGAGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA

TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGCAGTGGTTCGCTGGTGACAGCACGTTGTGCG

CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA

ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC

CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG

GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT

AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG

TTTGA

Domains

Predicted by InterProScan.

DprA winged helix domain (WHD_DprA)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
dprA	Vibrio campbellii strain DS40M4	48.509	98.663	0.479
dprA	Vibrio cholerae O1 biovar El Tor strain E7946	44.865	98.93	0.444
dprA	Vibrio cholerae strain A1552	44.865	98.93	0.444
dprA	Haemophilus influenzae Rd KW20	45.401	90.107	0.409
dprA	Glaesserella parasuis strain SC1401	44.838	90.642	0.406
dprA	Legionella pneumophila strain ERS1305867	44.545	88.235	0.393

Detailed information NTG0493757